Basic Information
ID: ALA1954200
Type: Binding
Description: Inhibition of Trypanosoma brucei N-myristoyltransferase using [3H]myristoyl-CoA and GCGGSKVKPQPPQAK(biotin)-amide as substrate preincubated for 5 mins prior substrate addition measured after 50 mins by streptavidin-coated scintillation proximity assay
Organism: Trypanosoma brucei
Activity Charts
Bioactivity
Activity Types for Assay ALA1954200
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 495.44 | 3.62 | 3.62 |
| 265.34 | 1.84 | 1.84 |
| 337.45 | 2.77 | 2.77 |
| 323.42 | 2.76 | 2.76 |
| 365.50 | 3.64 | 3.64 |
| 365.50 | 3.82 | 3.82 |
| 408.52 | 2.30 | 2.30 |
| 295.36 | 2.14 | 2.14 |
| 345.42 | 3.07 | 3.07 |
| 306.39 | 2.82 | 2.82 |
| 320.41 | 3.12 | 3.12 |
| 324.40 | 3.03 | 3.03 |
| 324.40 | 3.03 | 3.03 |
| 305.40 | 3.42 | 3.42 |
| 319.43 | 3.10 | 3.10 |
| 351.47 | 2.45 | 2.45 |
| 344.23 | 2.60 | 2.60 |
| 358.26 | 2.62 | 2.62 |
| 308.18 | 3.05 | 3.05 |
| 364.29 | 4.10 | 4.10 |
| 344.23 | 2.60 | 2.60 |
| 343.25 | 2.77 | 2.77 |
| 294.20 | 3.41 | 3.41 |
| 295.18 | 3.38 | 3.38 |
| 358.26 | 2.28 | 2.28 |
| 308.18 | 3.05 | 3.05 |
| 290.35 | 1.71 | 1.71 |
| 290.35 | 1.71 | 1.71 |
| 334.23 | 3.14 | 3.14 |
| 413.12 | 3.91 | 3.91 |
| 331.40 | 2.02 | 2.02 |
| 351.43 | 1.07 | 1.07 |
| 362.48 | 3.27 | 3.27 |
| 334.40 | 1.72 | 1.72 |
| 348.43 | 1.75 | 1.75 |
| 322.39 | 1.80 | 1.80 |
| 453.35 | 3.91 | 3.91 |
| 300.77 | 1.89 | 1.89 |
| 371.47 | 2.84 | 2.84 |
| 410.50 | 3.33 | 3.33 |
| 442.59 | 2.93 | 2.93 |
| 394.50 | 0.98 | 0.98 |
| 407.54 | 0.89 | 0.89 |
| 393.52 | 0.55 | 0.55 |
| 392.53 | 2.13 | 2.13 |
| 435.60 | 1.67 | 1.67 |
| 366.49 | 1.60 | 1.60 |
| 406.56 | 2.38 | 2.38 |
| 469.62 | 2.47 | 2.47 |
| 421.57 | 1.28 | 1.28 |
| 389.49 | 1.93 | 1.93 |
| 419.56 | 0.72 | 0.72 |
| 433.58 | 1.11 | 1.11 |
| 483.64 | 2.46 | 2.46 |
| 493.63 | 2.20 | 2.20 |
| 461.37 | 5.36 | 5.36 |
| 522.50 | 4.56 | 4.56 |
| 495.48 | 5.65 | 5.65 |
| 495.44 | 3.62 | 3.62 |
| 465.41 | 4.46 | 4.46 |
| 522.50 | 4.56 | 4.56 |
| 495.48 | 5.65 | 5.65 |