Assay Report Card

Basic Information

ID: ALA1958723

Type: Functional

Description: Agonist activity at human GPR119 expressed in HEK293 cells co-transfected with pCRE-Luc assessed as induction in cAMP level after 6 hrs by luciferase reporter gene assay relative to 10 uM of 2-{[2-(4-Bromophenyl)-6-methylpyrimidin-4-yl]amino}ethanol

Organism: Homo sapiens

Cell type: HEK293

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
263.732.512.51
355.182.462.46
322.212.872.87
344.163.253.25
322.213.013.01
322.213.013.01
322.213.273.27
320.234.284.28
355.244.224.22
369.274.264.26
385.273.503.50