Basic Information
ID: ALA1958724
Type: Functional
Description: Agonist activity at human GPR119 expressed in HEK293 cells co-transfected with pCRE-Luc assessed as induction in cAMP level at 10 uM after 6 hrs by luciferase reporter gene assay relative to 10 uM of 2-{[2-(4-Bromophenyl)-6-methylpyrimidin-4-yl]amino}ethanol
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA1958724
Intrinsic activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 229.28 | 1.86 | 1.86 |
| 263.73 | 2.51 | 2.51 |
| 355.18 | 2.46 | 2.46 |
| 259.31 | 1.86 | 1.86 |
| 243.31 | 2.16 | 2.16 |
| 294.15 | 2.31 | 2.31 |
| 322.21 | 2.87 | 2.87 |
| 336.23 | 3.26 | 3.26 |
| 336.23 | 3.43 | 3.43 |
| 344.16 | 3.25 | 3.25 |
| 362.15 | 3.33 | 3.33 |
| 322.21 | 2.64 | 2.64 |
| 322.21 | 3.01 | 3.01 |
| 322.21 | 3.01 | 3.01 |
| 322.21 | 3.27 | 3.27 |
| 320.23 | 4.28 | 4.28 |
| 355.24 | 4.22 | 4.22 |
| 369.27 | 4.26 | 4.26 |
| 385.27 | 3.50 | 3.50 |