Basic Information
ID: ALA1960402
Type: Functional
Description: Antagonist activity at vasoactive intestinal peptide receptor 1 in rat RKE cells assessed as inhibition of VIP-induced intracellular cAMP accumulation incubated for 10 mins prior to VIP-stimulation measured after 30 mins by HTRF assay
Format: BAO_0000219
Organism: Rattus norvegicus
Cell type: RKE
Target: Vasoactive intestinal polypeptide receptor 1(ALA1955712)
Document: ALA1955783
Antagonist activity at vasoactive intestinal peptide receptor 1 in rat RKE cells assessed as inhibition of VIP-induced intracellular cAMP accumulation incubated for 10 mins prior to VIP-stimulation measured after 30 mins by HTRF assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA1960402
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 282.37 | 3.75 | 3.75 |
| 296.39 | 3.68 | 3.68 |
| 288.42 | 4.02 | 4.02 |
| 220.30 | 2.46 | 2.46 |
| 248.35 | 3.09 | 3.09 |
| 296.45 | 5.58 | 5.58 |
| 350.42 | 6.29 | 6.29 |
| 307.44 | 5.14 | 5.14 |
| 358.53 | 6.93 | 6.93 |
| 312.45 | 5.28 | 5.28 |
| 328.52 | 5.99 | 5.99 |
| 312.45 | 5.28 | 5.28 |
| 312.45 | 5.28 | 5.28 |
| 300.42 | 5.41 | 5.41 |
| 358.53 | 6.93 | 6.93 |
| 282.43 | 5.27 | 5.27 |
| 325.50 | 5.33 | 5.33 |
| 296.45 | 5.58 | 5.58 |
| 316.87 | 5.92 | 5.92 |
| 296.45 | 5.58 | 5.58 |
| 358.53 | 6.93 | 6.93 |
| 332.49 | 6.42 | 6.42 |
| 332.49 | 6.42 | 6.42 |
| 316.87 | 5.92 | 5.92 |
| 310.48 | 5.88 | 5.88 |
| 234.32 | 2.85 | 2.85 |
| 262.38 | 3.48 | 3.48 |
| 246.34 | 2.85 | 2.85 |
| 260.36 | 3.24 | 3.24 |
| 274.39 | 3.63 | 3.63 |
| 310.42 | 4.07 | 4.07 |
| 324.45 | 4.38 | 4.38 |
| 324.45 | 4.38 | 4.38 |
| 324.45 | 4.38 | 4.38 |
| 340.45 | 4.08 | 4.08 |
| 340.45 | 4.08 | 4.08 |
| 344.87 | 4.72 | 4.72 |
| 352.48 | 4.89 | 4.89 |
| 338.43 | 3.83 | 3.83 |
| 335.43 | 4.16 | 4.16 |
| 336.46 | 4.24 | 4.24 |
| 322.43 | 3.85 | 3.85 |
| 312.39 | 3.52 | 3.52 |