Basic Information
ID: ALA1960616
Type: Functional
Description: Antimalarial activity against Plasmodium falciparum 3D7 0087/N9 infected in human RBC engrafted NOD-SCID IL-2Rgamma-null mouse assessed as reduction in parasitemia administered orally 3 days post infection qd for 4 days measured 24 hrs after final dose by FACS analysis
Organism: Plasmodium falciparum
Strain: 3D7 0087/N9
Activity Charts
Bioactivity
Activity Types for Assay ALA1960616
ED50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 319.88 | 4.81 | 4.81 |
| 384.43 | 2.60 | 2.60 |
| 357.29 | 4.31 | 4.31 |
| 329.23 | 3.47 | 3.47 |
| 415.34 | 5.95 | 5.95 |