Basic Information
ID: ALA1960721
Type: Binding
Description: Inhibition of MAPKAPK5 in synovial fibroblast from rheumatoid arthritis patient assessed as inhibition of TNF-alpha-induced MMP1 expression incubated for 30 mins prior to TNFalpha-challenge measured after 48 hrs by ELISA
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA1960721
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 361.41 | 2.70 | 2.70 |
| 362.40 | 2.09 | 2.09 |
| 414.47 | 3.08 | 3.08 |
| 450.52 | 2.62 | 2.62 |
| 432.46 | 3.21 | 3.21 |
| 388.43 | 2.66 | 2.66 |
| 420.50 | 3.14 | 3.14 |
| 421.49 | 2.53 | 2.53 |
| 421.49 | 2.53 | 2.53 |
| 420.50 | 3.14 | 3.14 |
| 426.48 | 3.22 | 3.22 |
| 427.47 | 2.61 | 2.61 |
| 404.43 | 2.67 | 2.67 |
| 404.43 | 2.67 | 2.67 |
| 401.47 | 2.58 | 2.58 |
| 362.40 | 2.09 | 2.09 |