Assay Report Card

Basic Information

ID: ALA1960748

Type: Binding

Description: Inhibition of Dengue virus NS2B-NS3 protease using Abz-NleKRRS-3-(NO2)Y as substrate at 50 uM preincubated for 15 mins measured every sec for 15 mins by fluorimetric analysis

Organism: Dengue virus

Activity Charts

Bioactivity

Activity Types for Assay ALA1960748

Inhibition

Total(163)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
202.21	1.18	1.18
218.21	0.88	0.88
218.21	0.88	0.88
227.22	1.35	1.35
257.08	2.17	2.17
188.19	0.87	0.87
238.25	2.02	2.02
194.22	0.93	0.93
178.15	0.46	0.46
218.21	0.88	0.88
204.19	0.57	0.57
204.19	0.57	0.57
233.18	0.78	0.78
231.25	0.93	0.93
266.30	2.08	2.08
237.31	2.32	2.32
221.31	2.18	2.18
246.32	2.05	2.05
117.13	-0.03	-0.03
205.24	2.01	2.01
207.25	1.58	1.58
221.24	1.72	1.72
235.26	2.02	2.02
100.08	-1.17	-1.17
133.20	0.13	0.13
235.33	2.48	2.48
251.33	2.18	2.18
222.29	1.57	1.57
251.26	1.72	1.72
281.36	2.19	2.19
265.29	2.03	2.03
267.33	1.89	1.89
253.30	1.59	1.59
251.33	2.18	2.18
237.31	1.88	1.88
264.38	2.24	2.24
219.26	2.52	2.52
235.26	2.02	2.02
248.31	2.08	2.08
237.31	1.88	1.88
251.33	2.18	2.18
271.37	3.33	3.33
255.30	3.16	3.16
215.34	2.60	2.60
235.33	2.57	2.57
243.29	1.51	1.51
234.21	0.58	0.58
248.24	0.88	0.88
221.24	1.72	1.72
274.13	3.32	3.32
190.20	0.44	0.44
206.23	1.41	1.41
260.32	1.60	1.60
244.28	2.49	2.49
260.34	2.66	2.66
204.25	1.03	1.03
218.28	1.42	1.42
254.31	2.19	2.19
268.34	2.58	2.58
285.39	3.72	3.72
269.33	3.55	3.55
273.14	2.34	2.34
290.20	3.48	3.48
294.20	1.73	1.73
311.26	2.87	2.87
278.14	1.56	1.56
295.19	2.71	2.71
249.25	0.94	0.94
250.24	1.92	1.92
247.32	1.10	1.10
218.28	1.34	1.34
285.33	1.65	1.65
302.38	2.79	2.79
286.31	2.63	2.63
257.32	1.52	1.52
274.37	2.67	2.67
241.25	1.36	1.36
258.30	2.50	2.50
234.28	1.04	1.04
220.25	0.74	0.74
234.28	1.04	1.04
220.25	0.74	0.74
264.31	1.05	1.05
236.25	0.44	0.44
220.18	0.28	0.28
244.73	1.75	1.75
261.78	2.89	2.89
228.66	1.58	1.58
245.71	2.73	2.73
289.18	1.86	1.86
306.23	3.00	3.00
273.11	1.69	1.69
290.16	2.83	2.83
244.73	1.75	1.75
261.78	2.89	2.89
228.66	1.58	1.58
245.71	2.73	2.73
289.18	1.86	1.86
306.23	3.00	3.00
224.31	1.48	1.48
241.36	2.63	2.63
205.24	0.43	0.43
237.24	1.42	1.42
250.28	0.75	0.75
234.28	1.04	1.04
235.26	2.02	2.02
210.28	1.09	1.09
227.34	2.24	2.24
211.27	2.07	2.07
194.22	0.62	0.62
211.27	1.77	1.77
195.20	1.60	1.60
289.18	1.86	1.86
306.23	3.00	3.00
273.11	1.69	1.69
290.16	2.83	2.83
246.29	1.18	1.18
263.34	2.33	2.33
247.28	2.16	2.16
194.22	-0.25	-0.25
211.27	0.90	0.90
229.26	0.90	0.90
184.26	0.72	0.72
201.32	1.86	1.86
198.29	1.11	1.11
215.34	2.25	2.25
184.26	1.06	1.06
198.29	1.45	1.45
210.30	1.45	1.45
227.35	2.60	2.60
211.29	2.43	2.43
300.43	3.47	3.47
236.32	1.76	1.76
243.29	1.51	1.51
236.27	1.56	1.56
253.32	2.70	2.70
280.35	2.45	2.45
220.25	1.18	1.18
221.24	2.16	2.16
277.37	2.74	2.74
261.30	2.58	2.58
116.14	-1.01	-1.01
214.29	0.66	0.66
172.25	0.41	0.41
229.26	-1.12	-1.12
187.22	-1.38	-1.38
248.31	0.86	0.86
206.27	0.60	0.60
248.31	0.86	0.86
206.27	0.60	0.60
190.20	0.44	0.44
223.32	1.75	1.75
229.30	-0.25	-0.25
187.27	-0.51	-0.51
264.31	0.57	0.57
222.27	0.31	0.31
238.27	0.01	0.01
222.20	-0.15	-0.15
212.30	0.66	0.66
196.23	0.50	0.50
287.34	1.34	1.34
245.31	1.08	1.08
229.24	0.92	0.92