Assay Report Card

Basic Information

ID: ALA1960750

Type: Binding

Description: Inhibition of Escherichia coli MurA using PEP as substrate assessed as inorganic phosphate release at 25 uM preincubated for 10 mins measured after 60 mins by fluorimetric assay

Organism: Escherichia coli

Activity Charts

Bioactivity

Activity Types for Assay ALA1960750

Inhibition

Total(163)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
202.21	1.18	1.18
218.21	0.88	0.88
218.21	0.88	0.88
227.22	1.35	1.35
257.08	2.17	2.17
188.19	0.87	0.87
238.25	2.02	2.02
194.22	0.93	0.93
178.15	0.46	0.46
218.21	0.88	0.88
204.19	0.57	0.57
204.19	0.57	0.57
233.18	0.78	0.78
231.25	0.93	0.93
266.30	2.08	2.08
237.31	2.32	2.32
221.31	2.18	2.18
246.32	2.05	2.05
117.13	-0.03	-0.03
205.24	2.01	2.01
207.25	1.58	1.58
221.24	1.72	1.72
235.26	2.02	2.02
100.08	-1.17	-1.17
133.20	0.13	0.13
235.33	2.48	2.48
251.33	2.18	2.18
222.29	1.57	1.57
251.26	1.72	1.72
281.36	2.19	2.19
265.29	2.03	2.03
267.33	1.89	1.89
253.30	1.59	1.59
251.33	2.18	2.18
237.31	1.88	1.88
264.38	2.24	2.24
219.26	2.52	2.52
235.26	2.02	2.02
248.31	2.08	2.08
237.31	1.88	1.88
251.33	2.18	2.18
271.37	3.33	3.33
255.30	3.16	3.16
215.34	2.60	2.60
235.33	2.57	2.57
243.29	1.51	1.51
234.21	0.58	0.58
248.24	0.88	0.88
221.24	1.72	1.72
274.13	3.32	3.32
190.20	0.44	0.44
206.23	1.41	1.41
260.32	1.60	1.60
244.28	2.49	2.49
260.34	2.66	2.66
204.25	1.03	1.03
218.28	1.42	1.42
254.31	2.19	2.19
268.34	2.58	2.58
285.39	3.72	3.72
269.33	3.55	3.55
273.14	2.34	2.34
290.20	3.48	3.48
294.20	1.73	1.73
311.26	2.87	2.87
278.14	1.56	1.56
295.19	2.71	2.71
249.25	0.94	0.94
250.24	1.92	1.92
247.32	1.10	1.10
218.28	1.34	1.34
285.33	1.65	1.65
302.38	2.79	2.79
286.31	2.63	2.63
257.32	1.52	1.52
274.37	2.67	2.67
241.25	1.36	1.36
258.30	2.50	2.50
234.28	1.04	1.04
220.25	0.74	0.74
234.28	1.04	1.04
220.25	0.74	0.74
264.31	1.05	1.05
236.25	0.44	0.44
220.18	0.28	0.28
244.73	1.75	1.75
261.78	2.89	2.89
228.66	1.58	1.58
245.71	2.73	2.73
289.18	1.86	1.86
306.23	3.00	3.00
273.11	1.69	1.69
290.16	2.83	2.83
244.73	1.75	1.75
261.78	2.89	2.89
228.66	1.58	1.58
245.71	2.73	2.73
289.18	1.86	1.86
306.23	3.00	3.00
224.31	1.48	1.48
241.36	2.63	2.63
205.24	0.43	0.43
237.24	1.42	1.42
250.28	0.75	0.75
234.28	1.04	1.04
235.26	2.02	2.02
210.28	1.09	1.09
227.34	2.24	2.24
211.27	2.07	2.07
194.22	0.62	0.62
211.27	1.77	1.77
195.20	1.60	1.60
289.18	1.86	1.86
306.23	3.00	3.00
273.11	1.69	1.69
290.16	2.83	2.83
246.29	1.18	1.18
263.34	2.33	2.33
247.28	2.16	2.16
194.22	-0.25	-0.25
211.27	0.90	0.90
229.26	0.90	0.90
184.26	0.72	0.72
201.32	1.86	1.86
198.29	1.11	1.11
215.34	2.25	2.25
184.26	1.06	1.06
198.29	1.45	1.45
210.30	1.45	1.45
227.35	2.60	2.60
211.29	2.43	2.43
300.43	3.47	3.47
236.32	1.76	1.76
243.29	1.51	1.51
236.27	1.56	1.56
253.32	2.70	2.70
280.35	2.45	2.45
220.25	1.18	1.18
221.24	2.16	2.16
277.37	2.74	2.74
261.30	2.58	2.58
116.14	-1.01	-1.01
214.29	0.66	0.66
172.25	0.41	0.41
229.26	-1.12	-1.12
187.22	-1.38	-1.38
248.31	0.86	0.86
206.27	0.60	0.60
248.31	0.86	0.86
206.27	0.60	0.60
190.20	0.44	0.44
223.32	1.75	1.75
229.30	-0.25	-0.25
187.27	-0.51	-0.51
264.31	0.57	0.57
222.27	0.31	0.31
238.27	0.01	0.01
222.20	-0.15	-0.15
212.30	0.66	0.66
196.23	0.50	0.50
287.34	1.34	1.34
245.31	1.08	1.08
229.24	0.92	0.92