Basic Information
ID: ALA1961096
Type: Binding
Description: Inhibition of Plasmodium falciparum C-terminal hexa-His tagged DHODH expressed in Escherichia coli by DCIP reduction assay
Format: BAO_0000019
Organism: Plasmodium falciparum
Target: Dihydroorotate dehydrogenase(ALA3486)
Document: ALA1955725
Inhibition of Plasmodium falciparum C-terminal hexa-His tagged DHODH expressed in Escherichia coli by DCIP reduction assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA1961096
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 357.29 | 4.31 | 4.31 |
| 315.81 | 4.03 | 4.03 |
| 315.81 | 4.03 | 4.03 |
| 287.75 | 3.39 | 3.39 |
| 287.75 | 3.39 | 3.39 |
| 321.31 | 3.76 | 3.76 |
| 379.36 | 5.40 | 5.40 |
| 301.78 | 3.95 | 3.95 |
| 301.78 | 3.95 | 3.95 |
| 335.33 | 4.32 | 4.32 |
| 393.38 | 5.96 | 5.96 |
| 349.36 | 4.39 | 4.39 |
| 407.41 | 6.03 | 6.03 |
| 349.36 | 4.49 | 4.49 |
| 407.41 | 6.13 | 6.13 |
| 349.36 | 4.71 | 4.71 |
| 407.41 | 6.35 | 6.35 |
| 299.77 | 3.71 | 3.71 |
| 299.77 | 3.71 | 3.71 |
| 333.32 | 4.07 | 4.07 |
| 391.37 | 5.71 | 5.71 |
| 313.79 | 3.78 | 3.78 |
| 313.79 | 3.78 | 3.78 |
| 347.34 | 4.15 | 4.15 |
| 405.40 | 5.79 | 5.79 |
| 323.73 | 3.94 | 3.94 |
| 323.73 | 3.94 | 3.94 |
| 415.34 | 5.95 | 5.95 |
| 337.76 | 4.33 | 4.33 |
| 337.76 | 4.33 | 4.33 |
| 371.31 | 4.70 | 4.70 |
| 429.37 | 6.34 | 6.34 |
| 361.25 | 4.21 | 4.21 |
| 419.30 | 5.85 | 5.85 |
| 303.75 | 2.98 | 2.98 |
| 303.75 | 2.98 | 2.98 |
| 337.31 | 3.34 | 3.34 |
| 395.36 | 4.98 | 4.98 |
| 317.78 | 3.02 | 3.02 |
| 317.78 | 3.02 | 3.02 |
| 351.33 | 3.38 | 3.38 |
| 409.38 | 5.02 | 5.02 |
| 305.79 | 3.55 | 3.55 |
| 305.79 | 3.55 | 3.55 |
| 339.35 | 3.92 | 3.92 |
| 397.40 | 5.56 | 5.56 |
| 337.79 | 2.23 | 2.23 |
| 337.79 | 2.23 | 2.23 |
| 371.34 | 2.60 | 2.60 |
| 429.40 | 4.24 | 4.24 |
| 289.73 | 2.84 | 2.84 |
| 289.73 | 2.84 | 2.84 |
| 303.75 | 3.23 | 3.23 |
| 303.75 | 3.23 | 3.23 |
| 337.31 | 3.59 | 3.59 |
| 395.36 | 5.23 | 5.23 |
| 333.78 | 2.85 | 2.85 |
| 333.78 | 2.85 | 2.85 |
| 332.80 | 2.43 | 2.43 |
| 332.80 | 2.43 | 2.43 |
| 366.35 | 2.79 | 2.79 |
| 424.40 | 4.43 | 4.43 |
| 346.82 | 2.77 | 2.77 |
| 346.82 | 2.77 | 2.77 |
| 380.37 | 3.14 | 3.14 |
| 438.43 | 4.77 | 4.77 |
| 318.77 | 2.17 | 2.17 |
| 352.32 | 2.53 | 2.53 |
| 318.77 | 2.17 | 2.17 |
| 275.70 | 2.12 | 2.12 |
| 275.70 | 2.12 | 2.12 |
| 316.80 | 2.59 | 2.59 |
| 288.74 | 2.29 | 2.29 |
| 302.77 | 2.55 | 2.55 |
| 316.80 | 2.89 | 2.89 |
| 316.80 | 2.59 | 2.59 |
| 316.80 | 2.89 | 2.89 |
| 288.74 | 2.29 | 2.29 |
| 302.77 | 2.55 | 2.55 |
| 302.77 | 2.33 | 2.33 |
| 289.73 | 2.32 | 2.32 |
| 289.73 | 2.32 | 2.32 |
| 337.31 | 2.73 | 2.73 |