Basic Information
ID: ALA1961978
Type: Binding
Description: GSK_PKIS: MELK mean inhibition at 0.1 uM [Nanosyn]
Format: BAO_0000357
Target: Maternal embryonic leucine zipper kinase(ALA4578)
Document: ALA1961873
GSK_PKIS: MELK mean inhibition at 0.1 uM [Nanosyn]: 16
Activity Charts
Bioactivity
Activity Types for Assay ALA1961978
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 440.48 | 4.73 | 4.73 |
| 415.47 | 4.86 | 4.86 |
| 366.44 | 3.47 | 3.47 |
| 483.47 | 5.88 | 5.88 |
| 395.47 | 4.23 | 4.23 |
| 358.41 | 3.58 | 3.58 |
| 428.52 | 5.16 | 5.16 |
| 352.42 | 3.00 | 3.00 |
| 348.36 | 2.31 | 2.31 |
| 370.43 | 2.95 | 2.95 |
| 377.18 | 3.17 | 3.17 |
| 349.17 | 3.18 | 3.18 |
| 326.35 | 4.11 | 4.11 |
| 401.49 | 4.12 | 4.12 |
| 392.86 | 4.54 | 4.54 |
| 287.33 | 3.39 | 3.39 |
| 348.37 | 2.95 | 2.95 |
| 490.45 | 5.39 | 5.39 |
| 496.88 | 6.28 | 6.28 |
| 573.56 | 5.18 | 5.18 |
| 230.23 | 1.08 | 1.08 |
| 284.32 | 2.57 | 2.57 |
| 258.29 | 1.65 | 1.65 |
| 216.20 | 0.60 | 0.60 |
| 340.43 | 5.32 | 5.32 |
| 344.38 | 3.47 | 3.47 |
| 393.45 | 6.21 | 6.21 |
| 307.18 | 3.92 | 3.92 |
| 484.52 | 4.19 | 4.19 |
| 381.46 | 3.07 | 3.07 |
| 228.25 | 1.86 | 1.86 |
| 300.36 | 3.89 | 3.89 |
| 453.57 | 5.72 | 5.72 |
| 345.37 | 2.94 | 2.94 |
| 308.34 | 2.98 | 2.98 |
| 430.31 | 3.37 | 3.37 |
| 347.17 | 3.33 | 3.33 |
| 394.43 | 5.14 | 5.14 |
| 467.51 | 1.12 | 1.12 |
| 415.47 | 2.55 | 2.55 |
| 370.43 | 2.53 | 2.53 |
| 383.39 | 1.76 | 1.76 |
| 330.37 | 1.41 | 1.41 |
| 367.39 | 1.65 | 1.65 |
| 566.06 | 5.59 | 5.59 |
| 603.17 | 6.67 | 6.67 |
| 467.98 | 7.53 | 7.53 |
| 476.48 | 5.90 | 5.90 |
| 491.49 | 5.06 | 5.06 |
| 505.52 | 5.40 | 5.40 |
| 379.44 | 3.77 | 3.77 |
| 423.49 | 3.82 | 3.82 |
| 457.94 | 5.00 | 5.00 |
| 427.91 | 4.99 | 4.99 |
| 461.47 | 5.35 | 5.35 |
| 362.47 | 4.08 | 4.08 |
| 336.44 | 4.15 | 4.15 |
| 454.46 | 3.70 | 3.70 |
| 518.60 | 4.22 | 4.22 |
| 568.05 | 5.60 | 5.60 |
| 508.63 | 5.53 | 5.53 |
| 481.60 | 5.35 | 5.35 |
| 517.61 | 5.28 | 5.28 |
| 528.62 | 7.34 | 7.34 |
| 289.31 | 4.20 | 4.20 |
| 352.44 | 2.23 | 2.23 |
| 395.47 | 1.80 | 1.80 |
| 447.50 | 2.28 | 2.28 |
| 447.50 | 2.28 | 2.28 |
| 275.31 | 3.07 | 3.07 |
| 472.52 | 3.89 | 3.89 |
| 374.40 | 3.03 | 3.03 |
| 303.32 | 2.67 | 2.67 |
| 332.79 | 4.10 | 4.10 |
| 297.74 | 3.96 | 3.96 |
| 302.76 | 4.09 | 4.09 |
| 487.97 | 3.71 | 3.71 |
| 409.92 | 3.73 | 3.73 |
| 370.39 | 4.04 | 4.04 |
| 561.52 | 2.28 | 2.28 |
| 379.85 | 4.31 | 4.31 |
| 488.33 | 5.83 | 5.83 |
| 539.87 | 6.34 | 6.34 |
| 587.94 | 5.38 | 5.38 |
| 556.93 | 7.07 | 7.07 |
| 532.78 | 5.94 | 5.94 |
| 453.89 | 5.18 | 5.18 |
| 497.90 | 4.88 | 4.88 |
| 420.86 | 3.63 | 3.63 |
| 447.93 | 4.79 | 4.79 |
| 359.79 | 3.20 | 3.20 |
| 565.10 | 5.35 | 5.35 |
| 565.10 | 5.35 | 5.35 |
| 579.10 | 5.92 | 5.92 |
| 595.55 | 6.43 | 6.43 |
| 364.81 | 2.06 | 2.06 |
| 547.47 | 4.41 | 4.41 |
| 374.85 | 2.65 | 2.65 |
| 393.87 | 4.96 | 4.96 |
| 413.31 | 4.62 | 4.62 |