Basic Information
ID: ALA1963824
Type: Functional
Description: PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member name: CDK8
Activity Charts
Bioactivity
Activity Types for Assay ALA1963824
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 377.44 | 4.68 | 4.68 |
| 384.40 | 3.63 | 3.63 |
| 319.14 | 0.95 | 0.95 |
| 393.44 | 3.41 | 3.41 |
| 581.07 | 6.14 | 6.14 |
| 331.35 | 4.65 | 4.65 |
| 309.34 | 3.99 | 3.99 |
| 475.36 | 4.43 | 4.43 |
| 291.38 | 1.22 | 1.22 |
| 301.78 | 3.48 | 3.48 |
| 380.54 | 3.66 | 3.66 |
| 512.44 | 5.77 | 5.77 |
| 354.46 | 3.20 | 3.20 |
| 293.28 | 3.24 | 3.24 |
| 446.91 | 4.28 | 4.28 |
| 493.62 | 4.59 | 4.59 |
| 307.35 | 3.30 | 3.30 |
| 448.35 | 4.57 | 4.57 |
| 346.82 | 5.01 | 5.01 |
| 527.67 | 5.99 | 5.99 |
| 251.29 | 3.38 | 3.38 |
| 436.27 | 5.49 | 5.49 |
| 562.72 | 5.03 | 5.03 |
| 464.83 | 5.55 | 5.55 |
| 401.85 | 3.30 | 3.30 |
| 468.56 | 3.51 | 3.51 |
| 394.36 | 1.22 | 1.22 |
| 447.54 | 2.97 | 2.97 |
| 513.60 | 4.74 | 4.74 |
| 374.42 | 1.27 | 1.27 |
| 375.41 | 0.51 | 0.51 |
| 362.77 | 4.23 | 4.23 |
| 488.02 | 3.31 | 3.31 |
| 507.57 | 3.50 | 3.50 |
| 587.55 | 3.62 | 3.62 |
| 375.41 | 4.90 | 4.90 |
| 213.24 | 1.36 | 1.36 |
| 324.32 | 3.80 | 3.80 |
| 351.32 | 3.57 | 3.57 |
| 346.35 | 3.54 | 3.54 |
| 284.27 | 2.88 | 2.88 |
| 312.38 | 1.54 | 1.54 |
| 334.38 | 3.43 | 3.43 |
| 513.52 | 6.94 | 6.94 |
| 415.50 | 3.41 | 3.41 |
| 361.45 | 3.97 | 3.97 |
| 532.41 | 3.86 | 3.86 |
| 239.28 | 2.00 | 2.00 |
| 476.87 | 5.87 | 5.87 |
| 366.42 | 2.83 | 2.83 |
| 464.60 | 3.50 | 3.50 |
| 614.22 | 5.02 | 5.02 |
| 450.51 | 5.22 | 5.22 |
| 470.46 | 3.63 | 3.63 |
| 437.53 | 3.14 | 3.14 |
| 392.44 | 2.54 | 2.54 |
| 518.55 | 3.14 | 3.14 |
| 468.95 | 3.82 | 3.82 |
| 518.93 | 5.75 | 5.75 |
| 430.95 | 5.10 | 5.10 |
| 194.24 | 3.23 | 3.23 |
| 277.29 | 2.67 | 2.67 |
| 348.36 | 4.08 | 4.08 |
| 529.57 | 5.11 | 5.11 |
| 258.36 | 3.30 | 3.30 |
| 438.49 | 2.43 | 2.43 |
| 439.55 | 4.79 | 4.79 |
| 319.37 | 3.07 | 3.07 |
| 507.50 | 3.14 | 3.14 |
| 502.97 | 5.00 | 5.00 |
| 188.25 | 2.30 | 2.30 |
| 278.31 | 3.13 | 3.13 |
| 274.37 | 3.54 | 3.54 |
| 210.24 | 3.00 | 3.00 |
| 450.35 | 5.04 | 5.04 |
| 342.36 | 0.26 | 0.26 |
| 469.55 | 5.89 | 5.89 |
| 637.87 | 6.16 | 6.16 |
| 441.56 | 5.07 | 5.07 |
| 346.31 | 4.60 | 4.60 |
| 163.18 | 0.21 | 0.21 |
| 471.51 | 4.61 | 4.61 |
| 526.69 | 5.99 | 5.99 |
| 406.34 | 4.55 | 4.55 |
| 288.15 | 3.70 | 3.70 |
| 530.61 | 4.41 | 4.41 |
| 500.99 | 6.38 | 6.38 |
| 375.44 | 2.37 | 2.37 |
| 348.19 | 3.13 | 3.13 |
| 184.24 | 2.49 | 2.49 |
| 370.89 | 3.96 | 3.96 |
| 330.77 | 3.26 | 3.26 |
| 322.37 | 2.08 | 2.08 |
| 412.43 | 4.26 | 4.26 |
| 350.28 | 4.43 | 4.43 |
| 209.25 | 2.93 | 2.93 |
| 301.26 | 2.95 | 2.95 |
| 366.73 | 4.95 | 4.95 |
| 220.26 | 1.18 | 1.18 |
| 217.63 | 0.77 | 0.77 |
| 353.22 | 4.65 | 4.65 |
| 451.55 | 2.51 | 2.51 |
| 268.32 | 2.27 | 2.27 |
| 285.35 | 4.23 | 4.23 |
| 448.96 | 4.64 | 4.64 |
| 317.34 | 3.49 | 3.49 |
| 203.20 | 0.33 | 0.33 |
| 354.80 | 4.04 | 4.04 |
| 535.65 | 6.13 | 6.13 |
| 357.30 | 4.16 | 4.16 |
| 370.89 | 3.96 | 3.96 |
| 210.24 | 1.98 | 1.98 |
| 334.38 | 2.64 | 2.64 |
| 346.37 | 5.01 | 5.01 |
| 526.69 | 6.04 | 6.04 |
| 458.52 | 5.73 | 5.73 |
| 226.24 | 2.78 | 2.78 |
| 471.29 | 5.58 | 5.58 |
| 365.35 | 3.80 | 3.80 |
| 513.64 | 5.71 | 5.71 |
| 465.45 | 4.44 | 4.44 |
| 264.31 | 1.93 | 1.93 |
| 178.22 | 1.40 | 1.40 |
| 378.45 | 5.17 | 5.17 |
| 402.79 | 4.71 | 4.71 |
| 536.56 | 5.65 | 5.65 |
| 287.75 | 2.65 | 2.65 |
| 383.43 | 4.98 | 4.98 |
| 244.25 | 2.68 | 2.68 |
| 322.32 | 3.36 | 3.36 |
| 271.36 | 2.74 | 2.74 |
| 151.19 | 1.27 | 1.27 |
| 230.66 | 2.67 | 2.67 |
| 328.24 | 3.57 | 3.57 |
| 373.43 | 2.07 | 2.07 |
| 579.70 | 5.52 | 5.52 |
| 272.22 | 1.60 | 1.60 |
| 393.45 | 3.08 | 3.08 |
| 439.53 | 3.85 | 3.85 |
| 342.83 | 3.36 | 3.36 |
| 429.30 | 4.46 | 4.46 |
| 222.25 | 3.00 | 3.00 |
| 363.38 | 4.01 | 4.01 |
| 491.54 | 4.44 | 4.44 |
| 340.43 | 2.31 | 2.31 |
| 351.16 | 1.44 | 1.44 |
| 253.26 | 2.31 | 2.31 |
| 215.21 | 1.71 | 1.71 |
| 392.89 | 4.54 | 4.54 |
| 212.23 | 0.60 | 0.60 |
| 494.60 | 5.95 | 5.95 |
| 332.40 | 4.25 | 4.25 |
| 460.49 | 3.24 | 3.24 |
| 355.42 | 3.30 | 3.30 |
| 214.02 | 1.01 | 1.01 |
| 316.36 | 2.43 | 2.43 |
| 406.44 | 4.20 | 4.20 |
| 500.61 | 2.89 | 2.89 |
| 405.24 | 4.97 | 4.97 |
| 402.45 | 3.93 | 3.93 |
| 281.36 | 3.41 | 3.41 |
| 343.82 | 3.39 | 3.39 |
| 419.45 | 3.99 | 3.99 |
| 532.48 | 6.04 | 6.04 |
| 358.38 | 4.00 | 4.00 |
| 360.42 | 3.61 | 3.61 |
| 470.53 | 4.01 | 4.01 |
| 277.32 | 4.12 | 4.12 |
| 319.79 | 2.93 | 2.93 |
| 322.37 | 3.18 | 3.18 |
| 525.72 | 7.54 | 7.54 |
| 327.19 | 3.88 | 3.88 |
| 333.21 | 3.82 | 3.82 |
| 515.61 | 4.71 | 4.71 |
| 411.89 | 5.87 | 5.87 |
| 331.40 | 1.70 | 1.70 |
| 352.20 | 3.75 | 3.75 |
| 353.45 | 4.01 | 4.01 |
| 434.94 | 4.25 | 4.25 |
| 484.60 | 5.00 | 5.00 |
| 325.30 | 3.20 | 3.20 |
| 317.30 | 3.04 | 3.04 |
| 208.26 | 3.31 | 3.31 |
| 490.55 | 4.17 | 4.17 |
| 384.87 | 3.53 | 3.53 |
| 293.33 | 2.45 | 2.45 |
| 488.55 | 5.18 | 5.18 |
| 302.33 | 3.88 | 3.88 |
| 224.26 | 3.39 | 3.39 |
| 356.79 | 4.75 | 4.75 |
| 436.52 | 4.52 | 4.52 |
| 424.46 | 4.13 | 4.13 |
| 385.90 | 4.39 | 4.39 |
| 466.54 | 4.35 | 4.35 |
| 474.57 | 2.64 | 2.64 |
| 331.74 | 2.61 | 2.61 |
| 394.48 | 4.73 | 4.73 |
| 398.29 | 4.89 | 4.89 |
| 191.19 | 0.70 | 0.70 |
| 219.24 | 1.25 | 1.25 |
| 265.28 | 2.67 | 2.67 |
| 366.73 | 4.95 | 4.95 |
| 368.27 | 4.57 | 4.57 |
| 427.94 | 3.07 | 3.07 |
| 304.82 | 4.36 | 4.36 |
| 362.31 | 4.30 | 4.30 |
| 374.48 | 3.91 | 3.91 |
| 271.71 | 2.98 | 2.98 |
| 359.86 | 3.26 | 3.26 |
| 345.40 | 4.70 | 4.70 |
| 474.49 | 4.06 | 4.06 |
| 560.65 | 5.03 | 5.03 |
| 386.46 | 4.26 | 4.26 |
| 346.37 | 5.01 | 5.01 |
| 413.07 | 4.07 | 4.07 |
| 342.83 | 3.36 | 3.36 |
| 428.88 | 4.78 | 4.78 |
| 210.24 | 2.24 | 2.24 |
| 499.55 | 4.85 | 4.85 |
| 437.57 | 3.75 | 3.75 |
| 375.48 | 3.17 | 3.17 |
| 383.45 | 3.64 | 3.64 |
| 542.64 | 5.43 | 5.43 |
| 545.62 | 5.73 | 5.73 |
| 363.28 | 4.71 | 4.71 |
| 342.40 | 5.36 | 5.36 |
| 243.27 | 1.23 | 1.23 |
| 212.05 | 1.69 | 1.69 |
| 343.78 | 2.45 | 2.45 |
| 301.15 | 3.53 | 3.53 |
| 391.40 | 4.34 | 4.34 |
| 464.55 | 4.46 | 4.46 |
| 444.21 | 3.74 | 3.74 |
| 241.25 | 1.32 | 1.32 |
| 306.39 | 3.71 | 3.71 |
| 276.34 | 3.90 | 3.90 |
| 315.32 | 4.25 | 4.25 |
| 305.34 | 2.41 | 2.41 |
| 329.84 | 3.68 | 3.68 |
| 332.40 | 3.60 | 3.60 |
| 430.95 | 5.10 | 5.10 |
| 342.42 | 3.45 | 3.45 |
| 399.80 | 4.45 | 4.45 |
| 206.60 | 0.72 | 0.72 |
| 260.30 | 3.66 | 3.66 |
| 435.48 | 4.59 | 4.59 |
| 347.34 | 2.93 | 2.93 |
| 232.29 | 1.43 | 1.43 |
| 360.34 | 4.86 | 4.86 |
| 292.36 | 4.81 | 4.81 |
| 343.82 | 3.39 | 3.39 |
| 428.88 | 4.78 | 4.78 |
| 215.26 | 1.34 | 1.34 |
| 313.38 | 3.16 | 3.16 |
| 374.37 | 5.25 | 5.25 |
| 352.46 | 3.67 | 3.67 |
| 331.80 | 3.44 | 3.44 |
| 277.32 | 0.79 | 0.79 |
| 365.42 | 2.81 | 2.81 |
| 277.41 | 4.34 | 4.34 |
| 386.48 | 4.64 | 4.64 |
| 233.27 | 0.77 | 0.77 |
| 221.26 | 2.90 | 2.90 |
| 268.32 | 1.99 | 1.99 |
| 241.28 | 1.94 | 1.94 |
| 317.37 | 2.26 | 2.26 |
| 462.41 | 4.76 | 4.76 |
| 568.70 | 4.99 | 4.99 |
| 156.19 | 1.98 | 1.98 |
| 252.32 | 3.51 | 3.51 |
| 498.61 | 5.74 | 5.74 |
| 419.45 | 3.99 | 3.99 |
| 380.27 | 4.40 | 4.40 |
| 317.39 | 3.18 | 3.18 |
| 461.57 | 4.64 | 4.64 |
| 405.39 | 3.35 | 3.35 |
| 335.79 | 4.96 | 4.96 |
| 398.48 | 3.33 | 3.33 |
| 265.32 | 2.70 | 2.70 |
| 427.34 | 5.19 | 5.19 |
| 454.49 | 4.14 | 4.14 |
| 293.25 | 3.25 | 3.25 |
| 384.77 | 4.81 | 4.81 |
| 343.82 | 3.39 | 3.39 |
| 424.46 | 3.87 | 3.87 |
| 301.39 | 4.11 | 4.11 |
| 215.28 | 2.66 | 2.66 |
| 331.42 | 3.55 | 3.55 |
| 174.62 | 1.25 | 1.25 |
| 434.51 | 7.06 | 7.06 |
| 373.48 | 2.56 | 2.56 |
| 325.30 | 3.20 | 3.20 |
| 526.69 | 5.99 | 5.99 |
| 437.51 | 4.19 | 4.19 |
| 280.29 | 2.98 | 2.98 |
| 370.42 | 5.24 | 5.24 |
| 179.18 | -0.79 | -0.79 |
| 220.62 | 1.22 | 1.22 |
| 194.24 | 3.00 | 3.00 |
| 269.26 | 2.92 | 2.92 |
| 345.18 | 4.02 | 4.02 |
| 297.82 | 3.79 | 3.79 |
| 348.79 | 4.53 | 4.53 |
| 514.63 | 4.36 | 4.36 |
| 479.95 | 3.55 | 3.55 |
| 226.28 | 2.11 | 2.11 |
| 401.45 | 4.53 | 4.53 |
| 237.26 | 2.60 | 2.60 |
| 436.82 | 4.71 | 4.71 |
| 526.69 | 6.17 | 6.17 |
| 342.83 | 3.36 | 3.36 |
| 247.34 | 2.17 | 2.17 |
| 265.32 | 3.39 | 3.39 |
| 388.23 | 2.56 | 2.56 |
| 419.95 | 3.72 | 3.72 |
| 338.43 | 4.31 | 4.31 |
| 196.21 | 1.72 | 1.72 |
| 499.62 | 5.47 | 5.47 |
| 235.08 | 2.74 | 2.74 |
| 266.35 | 3.84 | 3.84 |
| 377.36 | 4.29 | 4.29 |
| 176.18 | 0.14 | 0.14 |
| 430.42 | 4.40 | 4.40 |
| 308.39 | 2.61 | 2.61 |
| 210.24 | 2.51 | 2.51 |
| 295.37 | 2.81 | 2.81 |
| 410.43 | 3.62 | 3.62 |
| 424.46 | 2.09 | 2.09 |
| 443.47 | 4.27 | 4.27 |
| 426.95 | 5.66 | 5.66 |
| 534.66 | 5.79 | 5.79 |
| 460.53 | 4.06 | 4.06 |
| 467.57 | 4.94 | 4.94 |
| 210.26 | 0.62 | 0.62 |
| 413.91 | 2.73 | 2.73 |
| 323.40 | 3.40 | 3.40 |
| 227.24 | 3.07 | 3.07 |
| 209.25 | 2.58 | 2.58 |
| 387.26 | 4.42 | 4.42 |
| 339.42 | 3.35 | 3.35 |
| 290.32 | 3.67 | 3.67 |
| 334.38 | 4.04 | 4.04 |
| 373.33 | 1.53 | 1.53 |
| 327.82 | 4.42 | 4.42 |
| 440.78 | 5.20 | 5.20 |
| 356.47 | 4.01 | 4.01 |
| 427.43 | 4.30 | 4.30 |
| 186.26 | 2.49 | 2.49 |
| 396.31 | 4.64 | 4.64 |
| 342.83 | 3.36 | 3.36 |
| 314.78 | 4.02 | 4.02 |
| 514.58 | 3.63 | 3.63 |
| 484.56 | 4.40 | 4.40 |
| 278.36 | 3.62 | 3.62 |
| 193.21 | 0.67 | 0.67 |
| 530.70 | 5.96 | 5.96 |
| 381.51 | 3.10 | 3.10 |
| 527.63 | 5.95 | 5.95 |
| 380.46 | 4.43 | 4.43 |
| 236.27 | 3.43 | 3.43 |
| 326.36 | 4.18 | 4.18 |
| 483.50 | 5.45 | 5.45 |
| 198.27 | 2.68 | 2.68 |
| 360.34 | 4.86 | 4.86 |
| 372.39 | 1.67 | 1.67 |
| 450.52 | 6.34 | 6.34 |
| 352.44 | 3.73 | 3.73 |
| 526.69 | 6.04 | 6.04 |
| 176.24 | 2.24 | 2.24 |
| 595.70 | 4.71 | 4.71 |
| 213.03 | 1.62 | 1.62 |
| 243.27 | 1.37 | 1.37 |
| 675.71 | 7.94 | 7.94 |
| 368.27 | 4.57 | 4.57 |
| 306.37 | 3.47 | 3.47 |
| 213.04 | 1.30 | 1.30 |
| 211.22 | 1.69 | 1.69 |
| 276.75 | 4.32 | 4.32 |
| 401.92 | 4.50 | 4.50 |
| 376.42 | 2.75 | 2.75 |
| 454.49 | 4.14 | 4.14 |
| 241.25 | 1.91 | 1.91 |
| 361.43 | 5.31 | 5.31 |
| 268.28 | 1.36 | 1.36 |
| 235.29 | 1.95 | 1.95 |
| 286.38 | 2.66 | 2.66 |
| 334.38 | 3.04 | 3.04 |
| 412.43 | 4.26 | 4.26 |
| 485.54 | 5.00 | 5.00 |
| 243.25 | 2.10 | 2.10 |
| 245.28 | 1.25 | 1.25 |
| 425.46 | 2.48 | 2.48 |
| 213.03 | 1.39 | 1.39 |
| 357.85 | 3.75 | 3.75 |
| 320.35 | 2.48 | 2.48 |
| 528.64 | 5.83 | 5.83 |
| 423.40 | 5.54 | 5.54 |
| 498.63 | 5.39 | 5.39 |
| 420.93 | 2.95 | 2.95 |
| 314.78 | 3.52 | 3.52 |
| 357.21 | 3.89 | 3.89 |
| 471.51 | 4.61 | 4.61 |
| 365.85 | 2.24 | 2.24 |
| 422.46 | 3.43 | 3.43 |
| 514.58 | 3.63 | 3.63 |
| 318.38 | 3.69 | 3.69 |
| 327.82 | 4.42 | 4.42 |
| 328.80 | 4.41 | 4.41 |
| 398.94 | 4.64 | 4.64 |
| 351.41 | 3.04 | 3.04 |
| 396.50 | 2.28 | 2.28 |
| 392.39 | 3.82 | 3.82 |
| 485.59 | 5.08 | 5.08 |
| 167.19 | 0.57 | 0.57 |
| 374.32 | 4.10 | 4.10 |
| 498.56 | 6.17 | 6.17 |
| 370.33 | 4.66 | 4.66 |
| 391.84 | 4.09 | 4.09 |
| 275.38 | 3.17 | 3.17 |
| 409.44 | 4.55 | 4.55 |
| 245.67 | 2.26 | 2.26 |
| 350.28 | 4.43 | 4.43 |