Basic Information
ID: ALA1963838
Type: Functional
Description: PUBCHEM_BIOASSAY: Luminescence-based cell-based high throughput dose response assay for inhibitors of the Steroid Receptor Coactivator 1 (SRC1; NCOA1). (Class of assay: confirmatory)
Activity Charts
Bioactivity
Activity Types for Assay ALA1963838
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 454.45 | 0.27 | 0.27 |
| 454.45 | 0.27 | 0.27 |
| 243.22 | -2.56 | -2.56 |
| 588.56 | 1.34 | 1.34 |
| 293.71 | 2.43 | 2.43 |
| 504.51 | 1.42 | 1.42 |
| 224.26 | 3.03 | 3.03 |
| 352.42 | 3.07 | 3.07 |
| 367.23 | 4.01 | 4.01 |
| 264.13 | 2.99 | 2.99 |
| 380.44 | 4.55 | 4.55 |
| 539.06 | 2.81 | 2.81 |
| 331.42 | 4.35 | 4.35 |
| 280.40 | 4.53 | 4.53 |
| 429.86 | 4.54 | 4.54 |
| 641.16 | 4.09 | 4.09 |
| 459.57 | 3.18 | 3.18 |
| 323.40 | 2.37 | 2.37 |
| 309.33 | 3.48 | 3.48 |
| 426.54 | 4.96 | 4.96 |
| 278.69 | 2.79 | 2.79 |
| 403.33 | 6.38 | 6.38 |
| 361.42 | 4.60 | 4.60 |
| 222.25 | 2.97 | 2.97 |
| 395.44 | 4.29 | 4.29 |
| 360.42 | 4.52 | 4.52 |
| 319.31 | 0.83 | 0.83 |
| 524.08 | 6.83 | 6.83 |
| 477.36 | 5.06 | 5.06 |
| 218.26 | 1.86 | 1.86 |
| 356.81 | 4.21 | 4.21 |
| 323.35 | 3.12 | 3.12 |
| 510.63 | 6.23 | 6.23 |
| 356.38 | 3.37 | 3.37 |
| 418.56 | 4.52 | 4.52 |
| 313.40 | 4.92 | 4.92 |
| 333.82 | 3.77 | 3.77 |
| 383.40 | 5.58 | 5.58 |
| 473.54 | 0.94 | 0.94 |
| 330.77 | 4.38 | 4.38 |
| 267.35 | 2.39 | 2.39 |
| 218.21 | 2.01 | 2.01 |
| 247.34 | 3.57 | 3.57 |
| 328.32 | 3.18 | 3.18 |
| 357.39 | 3.87 | 3.87 |
| 473.60 | 2.37 | 2.37 |
| 349.38 | 2.43 | 2.43 |
| 274.11 | 1.96 | 1.96 |
| 262.26 | 1.40 | 1.40 |
| 448.57 | 2.08 | 2.08 |
| 202.21 | 1.15 | 1.15 |
| 332.41 | 2.60 | 2.60 |
| 493.59 | 3.20 | 3.20 |
| 426.00 | 2.18 | 2.18 |
| 420.34 | 4.50 | 4.50 |
| 370.79 | 3.50 | 3.50 |
| 285.74 | 3.09 | 3.09 |
| 330.32 | 1.55 | 1.55 |
| 391.41 | 0.45 | 0.45 |
| 439.49 | 4.57 | 4.57 |
| 410.94 | 3.17 | 3.17 |
| 331.79 | 3.90 | 3.90 |
| 477.65 | 2.91 | 2.91 |
| 402.45 | 2.10 | 2.10 |
| 390.46 | 2.00 | 2.00 |
| 354.84 | 4.33 | 4.33 |
| 343.23 | 4.20 | 4.20 |
| 437.39 | 4.27 | 4.27 |
| 438.89 | 1.01 | 1.01 |
| 337.42 | 2.76 | 2.76 |
| 461.63 | 3.62 | 3.62 |
| 290.75 | 3.18 | 3.18 |
| 354.44 | 3.15 | 3.15 |
| 224.22 | 3.30 | 3.30 |
| 264.31 | 1.63 | 1.63 |
| 247.35 | 2.71 | 2.71 |
| 251.21 | 3.02 | 3.02 |
| 419.41 | 2.17 | 2.17 |
| 216.27 | 2.45 | 2.45 |
| 287.77 | 1.45 | 1.45 |
| 318.31 | 1.38 | 1.38 |
| 353.32 | 2.78 | 2.78 |
| 387.33 | 2.38 | 2.38 |
| 248.24 | 0.88 | 0.88 |
| 231.28 | 1.61 | 1.61 |
| 335.33 | 2.64 | 2.64 |
| 339.39 | 3.54 | 3.54 |
| 261.32 | 4.73 | 4.73 |
| 359.38 | 1.33 | 1.33 |
| 456.89 | 0.98 | 0.98 |
| 283.40 | 3.36 | 3.36 |
| 412.54 | 4.32 | 4.32 |
| 440.41 | 4.31 | 4.31 |
| 318.25 | 1.17 | 1.17 |
| 570.47 | 6.14 | 6.14 |
| 508.69 | 4.23 | 4.23 |
| 316.32 | 0.77 | 0.77 |
| 475.53 | 4.21 | 4.21 |
| 242.31 | 2.39 | 2.39 |
| 317.37 | 2.15 | 2.15 |
| 505.44 | 5.55 | 5.55 |
| 388.56 | 4.04 | 4.04 |
| 356.38 | 1.84 | 1.84 |
| 287.32 | 3.56 | 3.56 |
| 381.43 | 3.00 | 3.00 |
| 263.77 | 3.01 | 3.01 |
| 283.28 | 2.87 | 2.87 |
| 451.49 | 3.75 | 3.75 |
| 337.38 | 3.62 | 3.62 |
| 310.47 | 3.67 | 3.67 |
| 370.47 | 4.36 | 4.36 |
| 340.45 | 3.10 | 3.10 |
| 454.36 | 4.86 | 4.86 |
| 262.26 | 2.15 | 2.15 |
| 231.21 | 1.36 | 1.36 |
| 306.37 | 2.21 | 2.21 |
| 342.40 | 1.84 | 1.84 |
| 208.24 | 1.67 | 1.67 |
| 365.39 | 3.97 | 3.97 |
| 476.94 | 3.83 | 3.83 |
| 314.37 | 2.45 | 2.45 |
| 302.33 | 3.32 | 3.32 |
| 331.37 | 3.20 | 3.20 |
| 332.75 | 3.30 | 3.30 |
| 390.55 | 3.37 | 3.37 |
| 479.03 | 4.22 | 4.22 |
| 430.51 | 2.48 | 2.48 |
| 487.65 | 3.72 | 3.72 |
| 454.96 | 4.73 | 4.73 |
| 265.32 | 3.69 | 3.69 |
| 237.26 | 3.04 | 3.04 |
| 230.31 | 3.47 | 3.47 |
| 349.43 | 2.93 | 2.93 |
| 339.42 | 3.02 | 3.02 |
| 450.59 | 3.84 | 3.84 |
| 186.24 | 2.84 | 2.84 |
| 358.49 | 3.43 | 3.43 |
| 363.85 | 4.96 | 4.96 |
| 270.40 | 4.42 | 4.42 |
| 364.49 | 3.89 | 3.89 |
| 294.76 | 3.26 | 3.26 |
| 341.48 | 1.61 | 1.61 |
| 454.69 | 5.63 | 5.63 |
| 443.88 | 3.90 | 3.90 |
| 451.45 | 5.00 | 5.00 |
| 431.17 | 2.97 | 2.97 |
| 351.45 | 3.92 | 3.92 |
| 387.43 | 2.73 | 2.73 |
| 435.50 | 4.33 | 4.33 |
| 656.66 | 2.75 | 2.75 |
| 292.77 | 3.43 | 3.43 |
| 373.41 | 2.73 | 2.73 |
| 385.45 | 4.09 | 4.09 |
| 273.76 | 3.33 | 3.33 |
| 406.83 | 2.77 | 2.77 |
| 373.42 | 4.33 | 4.33 |
| 238.29 | 3.07 | 3.07 |
| 243.22 | 2.24 | 2.24 |
| 280.12 | 3.00 | 3.00 |
| 318.36 | 4.09 | 4.09 |
| 361.45 | 4.31 | 4.31 |
| 225.29 | 2.90 | 2.90 |
| 326.47 | 2.64 | 2.64 |
| 360.21 | 4.15 | 4.15 |
| 294.76 | 3.26 | 3.26 |
| 338.32 | 2.60 | 2.60 |
| 208.22 | 2.67 | 2.67 |
| 230.30 | 1.40 | 1.40 |
| 366.46 | 3.60 | 3.60 |
| 462.33 | 3.91 | 3.91 |
| 209.28 | 0.29 | 0.29 |
| 425.44 | 1.68 | 1.68 |
| 293.33 | 2.70 | 2.70 |
| 240.22 | 2.80 | 2.80 |
| 339.39 | 5.18 | 5.18 |
| 517.63 | 5.29 | 5.29 |
| 591.82 | 5.73 | 5.73 |
| 391.49 | 2.86 | 2.86 |
| 338.41 | 0.50 | 0.50 |
| 318.34 | 2.98 | 2.98 |
| 348.43 | 2.03 | 2.03 |
| 229.24 | 1.94 | 1.94 |
| 323.44 | 1.80 | 1.80 |
| 355.39 | 2.57 | 2.57 |
| 278.31 | 3.52 | 3.52 |
| 379.21 | 2.01 | 2.01 |
| 723.65 | 2.46 | 2.46 |
| 232.29 | 4.18 | 4.18 |
| 245.31 | 0.98 | 0.98 |
| 511.88 | 3.58 | 3.58 |
| 399.43 | 2.66 | 2.66 |
| 433.70 | 3.19 | 3.19 |
| 404.37 | 2.38 | 2.38 |
| 234.23 | 1.60 | 1.60 |
| 195.22 | 2.42 | 2.42 |
| 479.54 | 4.63 | 4.63 |
| 284.23 | -0.84 | -0.84 |
| 461.65 | 3.07 | 3.07 |
| 499.64 | 3.86 | 3.86 |
| 442.23 | 1.99 | 1.99 |
| 280.35 | 3.48 | 3.48 |
| 383.28 | 5.14 | 5.14 |
| 383.40 | 1.69 | 1.69 |
| 352.46 | 3.81 | 3.81 |
| 429.33 | 2.73 | 2.73 |
| 335.79 | 3.92 | 3.92 |
| 369.38 | 2.66 | 2.66 |
| 204.23 | 3.26 | 3.26 |
| 326.35 | 2.01 | 2.01 |
| 285.30 | 1.95 | 1.95 |
| 410.43 | 2.79 | 2.79 |
| 362.43 | 3.64 | 3.64 |
| 385.38 | 0.81 | 0.81 |
| 341.37 | 2.28 | 2.28 |
| 391.43 | 3.29 | 3.29 |
| 347.30 | 4.05 | 4.05 |
| 197.19 | 2.34 | 2.34 |
| 390.24 | 3.02 | 3.02 |
| 419.28 | 2.07 | 2.07 |
| 368.35 | 2.19 | 2.19 |
| 291.36 | 3.30 | 3.30 |
| 288.31 | 2.76 | 2.76 |
| 427.93 | 4.21 | 4.21 |
| 410.48 | 4.46 | 4.46 |
| 385.85 | 2.12 | 2.12 |
| 342.74 | 2.92 | 2.92 |
| 408.48 | 3.56 | 3.56 |
| 267.28 | 3.07 | 3.07 |
| 455.56 | 3.76 | 3.76 |
| 306.41 | 1.57 | 1.57 |
| 307.31 | 2.26 | 2.26 |
| 314.35 | 2.16 | 2.16 |
| 289.36 | 2.78 | 2.78 |
| 310.35 | 2.31 | 2.31 |
| 253.26 | 2.68 | 2.68 |
| 521.62 | 2.79 | 2.79 |
| 243.22 | -2.56 | -2.56 |
| 879.86 | 6.39 | 6.39 |
| 311.43 | 2.00 | 2.00 |
| 526.54 | 1.21 | 1.21 |