Basic Information
ID: ALA1963849
Type: Functional
Description: PUBCHEM_BIOASSAY: SAR analysis of small molecule inhibitors of tim23-1: a luminescent tim10-1 yeast counterscreen. (Class of assay: confirmatory)
Activity Charts
Bioactivity
Activity Types for Assay ALA1963849
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 287.32 | 3.58 | 3.58 |
| 419.41 | 3.07 | 3.07 |
| 309.35 | 4.14 | 4.14 |
| 420.52 | 2.01 | 2.01 |
| 319.39 | 4.32 | 4.32 |
| 421.93 | 3.74 | 3.74 |
| 497.62 | 1.26 | 1.26 |
| 312.38 | 4.74 | 4.74 |
| 364.40 | 3.49 | 3.49 |
| 249.27 | 2.54 | 2.54 |
| 325.80 | 4.03 | 4.03 |
| 454.96 | 2.66 | 2.66 |
| 246.21 | 3.88 | 3.88 |
| 411.48 | 4.39 | 4.39 |
| 411.53 | 3.58 | 3.58 |
| 265.27 | 3.18 | 3.18 |
| 489.62 | 2.48 | 2.48 |
| 263.35 | 1.83 | 1.83 |
| 403.41 | 3.19 | 3.19 |
| 351.41 | 1.88 | 1.88 |
| 269.34 | 3.89 | 3.89 |
| 422.53 | 5.95 | 5.95 |
| 330.77 | 3.95 | 3.95 |
| 246.29 | 2.77 | 2.77 |
| 493.61 | 5.01 | 5.01 |
| 323.39 | 3.84 | 3.84 |
| 388.25 | 4.90 | 4.90 |
| 300.84 | 4.41 | 4.41 |
| 337.15 | 3.28 | 3.28 |
| 262.32 | 3.67 | 3.67 |
| 294.31 | 4.68 | 4.68 |
| 305.39 | 2.44 | 2.44 |
| 309.15 | 3.68 | 3.68 |
| 352.42 | 3.84 | 3.84 |
| 416.46 | 1.64 | 1.64 |
| 293.37 | 1.92 | 1.92 |
| 332.79 | 3.09 | 3.09 |
| 381.55 | 4.27 | 4.27 |
| 400.50 | 2.58 | 2.58 |
| 283.72 | 3.28 | 3.28 |
| 437.46 | 2.44 | 2.44 |
| 399.88 | 2.84 | 2.84 |
| 385.80 | 4.36 | 4.36 |
| 429.89 | 3.19 | 3.19 |
| 498.63 | 4.37 | 4.37 |
| 437.85 | 3.85 | 3.85 |
| 379.46 | 2.57 | 2.57 |
| 290.78 | 3.74 | 3.74 |
| 428.33 | 3.24 | 3.24 |
| 276.24 | 2.44 | 2.44 |
| 376.46 | 3.06 | 3.06 |
| 323.38 | 4.45 | 4.45 |
| 464.33 | 3.84 | 3.84 |
| 416.51 | 3.74 | 3.74 |
| 401.49 | 2.73 | 2.73 |
| 416.22 | 3.92 | 3.92 |
| 377.45 | 2.38 | 2.38 |
| 392.23 | 2.84 | 2.84 |
| 387.85 | 2.97 | 2.97 |
| 383.45 | 5.58 | 5.58 |
| 294.31 | 2.64 | 2.64 |
| 358.81 | 3.34 | 3.34 |
| 410.43 | 2.09 | 2.09 |
| 377.47 | 4.16 | 4.16 |
| 339.44 | 1.97 | 1.97 |
| 368.46 | 2.71 | 2.71 |
| 353.18 | 4.57 | 4.57 |
| 320.42 | 1.49 | 1.49 |
| 403.27 | 4.58 | 4.58 |
| 294.38 | 0.95 | 0.95 |
| 428.47 | 0.85 | 0.85 |
| 428.58 | 6.88 | 6.88 |
| 437.85 | 3.85 | 3.85 |
| 415.45 | 2.38 | 2.38 |
| 389.25 | 3.30 | 3.30 |
| 335.41 | 2.17 | 2.17 |
| 297.34 | 2.77 | 2.77 |
| 368.31 | 3.20 | 3.20 |
| 300.31 | 3.68 | 3.68 |
| 411.68 | 3.85 | 3.85 |
| 333.42 | 3.84 | 3.84 |
| 359.48 | 2.88 | 2.88 |
| 388.85 | 4.15 | 4.15 |
| 416.53 | 2.47 | 2.47 |
| 333.40 | 2.39 | 2.39 |
| 323.25 | 5.00 | 5.00 |
| 377.29 | 4.79 | 4.79 |
| 322.36 | 3.35 | 3.35 |
| 292.34 | 4.44 | 4.44 |
| 392.47 | 3.19 | 3.19 |
| 353.16 | 3.20 | 3.20 |
| 324.77 | 3.97 | 3.97 |
| 368.82 | 4.37 | 4.37 |
| 349.80 | 2.03 | 2.03 |
| 387.85 | 2.97 | 2.97 |
| 316.70 | 2.35 | 2.35 |
| 461.95 | 4.62 | 4.62 |
| 405.48 | 3.23 | 3.23 |
| 358.39 | 2.97 | 2.97 |
| 497.40 | 2.17 | 2.17 |
| 358.45 | 2.85 | 2.85 |
| 332.39 | 1.81 | 1.81 |
| 367.81 | 2.19 | 2.19 |
| 423.88 | 1.84 | 1.84 |
| 415.32 | 3.94 | 3.94 |
| 416.93 | 4.17 | 4.17 |
| 300.54 | 3.08 | 3.08 |
| 284.32 | 2.69 | 2.69 |
| 495.42 | 3.32 | 3.32 |
| 316.32 | 3.78 | 3.78 |
| 469.88 | 4.26 | 4.26 |
| 432.57 | 3.16 | 3.16 |
| 461.75 | 4.44 | 4.44 |
| 391.27 | 4.11 | 4.11 |
| 393.45 | 1.94 | 1.94 |
| 315.35 | 1.37 | 1.37 |
| 435.79 | 5.02 | 5.02 |
| 353.21 | 3.43 | 3.43 |
| 416.22 | 4.16 | 4.16 |
| 272.28 | 2.61 | 2.61 |
| 300.41 | 4.10 | 4.10 |
| 366.23 | 4.08 | 4.08 |
| 227.26 | 2.89 | 2.89 |
| 269.33 | 2.38 | 2.38 |