Basic Information
ID: ALA1963857
Type: Functional
Description: PUBCHEM_BIOASSAY: qHTS for Inhibitors of mutant isocitrate dehydrogenase 1 (IDH1): Cherrypicks in WT IDH1. (Class of assay: confirmatory)
Activity Charts
Bioactivity
Activity Types for Assay ALA1963857
Potency
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 380.35 | 3.63 | 3.63 |
| 481.60 | 5.29 | 5.29 |
| 334.37 | 4.65 | 4.65 |
| 186.21 | 1.34 | 1.34 |
| 392.49 | 6.00 | 6.00 |
| 687.71 | 10.29 | 10.29 |
| 373.88 | 6.26 | 6.26 |
| 381.48 | 4.74 | 4.74 |
| 392.41 | 4.85 | 4.85 |
| 452.51 | 4.22 | 4.22 |
| 402.54 | 4.63 | 4.63 |
| 385.47 | 4.29 | 4.29 |
| 379.42 | 4.02 | 4.02 |
| 499.51 | 4.19 | 4.19 |
| 441.51 | 2.96 | 2.96 |
| 332.15 | 4.03 | 4.03 |
| 499.57 | 2.82 | 2.82 |
| 376.48 | 5.36 | 5.36 |
| 285.35 | 4.62 | 4.62 |
| 350.16 | 2.74 | 2.74 |
| 470.98 | 5.51 | 5.51 |
| 385.26 | 5.16 | 5.16 |
| 416.19 | 5.17 | 5.17 |
| 565.38 | 5.32 | 5.32 |
| 284.43 | 4.46 | 4.46 |
| 374.51 | 5.91 | 5.91 |
| 422.55 | 3.52 | 3.52 |
| 339.42 | 3.09 | 3.09 |
| 396.83 | 4.68 | 4.68 |
| 402.55 | 2.93 | 2.93 |
| 302.81 | 3.41 | 3.41 |
| 405.54 | 5.19 | 5.19 |
| 303.35 | 3.68 | 3.68 |
| 514.65 | ||
| 501.97 | 4.46 | 4.46 |
| 369.23 | 3.13 | 3.13 |
| 443.89 | 5.49 | 5.49 |
| 493.99 | 5.25 | 5.25 |
| 479.58 | 4.53 | 4.53 |
| 510.49 | 3.67 | 3.67 |
| 414.55 | 4.68 | 4.68 |
| 374.27 | 1.20 | 1.20 |
| 448.59 | 5.17 | 5.17 |
| 332.35 | 2.98 | 2.98 |
| 281.43 | 3.74 | 3.74 |
| 513.08 | 3.72 | 3.72 |
| 304.24 | 2.71 | 2.71 |
| 374.35 | 4.51 | 4.51 |
| 312.33 | 3.40 | 3.40 |
| 282.37 | 2.47 | 2.47 |
| 383.88 | 0.94 | 0.94 |
| 291.31 | 3.28 | 3.28 |
| 316.74 | 3.53 | 3.53 |
| 487.54 | 2.95 | 2.95 |
| 413.48 | 3.87 | 3.87 |
| 385.45 | 2.47 | 2.47 |
| 331.35 | 3.35 | 3.35 |
| 329.38 | 3.96 | 3.96 |
| 414.49 | 3.80 | 3.80 |
| 422.52 | 5.83 | 5.83 |
| 358.43 | 3.69 | 3.69 |
| 283.36 | 2.32 | 2.32 |
| 318.36 | 3.42 | 3.42 |
| 415.45 | 4.44 | 4.44 |
| 459.32 | 4.79 | 4.79 |
| 374.19 | 3.90 | 3.90 |
| 321.34 | 3.82 | 3.82 |
| 468.98 | 6.27 | 6.27 |
| 257.25 | 3.39 | 3.39 |
| 497.98 | 4.27 | 4.27 |
| 314.37 | 2.13 | 2.13 |
| 427.89 | 4.41 | 4.41 |
| 450.39 | 3.57 | 3.57 |
| 519.62 | 3.80 | 3.80 |
| 408.42 | 4.65 | 4.65 |
| 376.87 | 3.57 | 3.57 |
| 466.54 | 4.61 | 4.61 |
| 337.42 | 2.96 | 2.96 |
| 303.32 | 1.52 | 1.52 |
| 408.46 | 3.81 | 3.81 |
| 360.47 | 1.84 | 1.84 |
| 350.42 | 3.31 | 3.31 |
| 379.39 | 3.47 | 3.47 |
| 467.51 | 2.42 | 2.42 |
| 408.37 | 2.98 | 2.98 |
| 385.38 | 4.73 | 4.73 |
| 370.50 | 3.23 | 3.23 |
| 304.19 | 4.05 | 4.05 |
| 320.85 | 4.35 | 4.35 |
| 376.41 | 5.15 | 5.15 |
| 359.39 | 3.36 | 3.36 |
| 489.94 | 4.59 | 4.59 |
| 446.21 | 4.46 | 4.46 |
| 214.22 | 2.50 | 2.50 |
| 400.55 | 4.03 | 4.03 |
| 479.99 | 4.13 | 4.13 |
| 370.48 | 3.69 | 3.69 |
| 244.28 | 2.79 | 2.79 |
| 257.25 | 3.39 | 3.39 |
| 495.99 | 3.83 | 3.83 |
| 393.53 | 4.88 | 4.88 |
| 305.83 | 4.63 | 4.63 |
| 275.31 | 3.58 | 3.58 |
| 308.37 | 2.19 | 2.19 |
| 383.26 | 3.44 | 3.44 |
| 295.35 | 1.20 | 1.20 |
| 472.34 | 4.60 | 4.60 |
| 478.89 | 5.28 | 5.28 |
| 450.61 | 4.32 | 4.32 |
| 422.40 | 3.29 | 3.29 |
| 455.49 | 5.23 | 5.23 |
| 464.35 | 4.87 | 4.87 |
| 498.46 | 5.49 | 5.49 |
| 366.42 | 5.46 | 5.46 |
| 277.66 | 3.74 | 3.74 |
| 400.50 | 3.70 | 3.70 |
| 257.25 | 3.39 | 3.39 |
| 444.40 | 2.54 | 2.54 |
| 481.55 | 4.20 | 4.20 |
| 469.77 | 4.58 | 4.58 |
| 484.56 | 5.11 | 5.11 |
| 303.32 | 3.81 | 3.81 |
| 484.60 | 5.43 | 5.43 |
| 505.32 | 5.69 | 5.69 |
| 495.56 | 4.79 | 4.79 |
| 386.29 | 3.72 | 3.72 |
| 455.51 | 4.29 | 4.29 |
| 353.85 | 5.16 | 5.16 |
| 457.58 | 3.13 | 3.13 |
| 354.18 | 4.83 | 4.83 |
| 399.47 | 2.86 | 2.86 |
| 432.48 | 3.94 | 3.94 |
| 387.46 | 4.10 | 4.10 |
| 399.47 | 2.86 | 2.86 |
| 392.96 | 3.27 | 3.27 |
| 425.44 | 4.53 | 4.53 |
| 367.88 | 1.10 | 1.10 |
| 332.43 | 2.22 | 2.22 |
| 305.83 | 4.63 | 4.63 |
| 285.39 | 4.17 | 4.17 |
| 444.63 | 4.11 | 4.11 |
| 518.55 | 7.38 | 7.38 |
| 335.49 | 5.99 | 5.99 |
| 423.47 | 5.09 | 5.09 |
| 469.55 | 2.81 | 2.81 |
| 510.02 | 4.14 | 4.14 |
| 275.31 | 3.58 | 3.58 |
| 355.44 | 4.83 | 4.83 |
| 339.40 | 4.01 | 4.01 |
| 399.45 | 5.37 | 5.37 |
| 385.45 | 2.47 | 2.47 |
| 425.44 | 4.53 | 4.53 |
| 290.27 | 0.63 | 0.63 |
| 315.38 | 2.04 | 2.04 |
| 421.01 | 4.00 | 4.00 |
| 499.53 | 6.20 | 6.20 |
| 432.31 | 4.67 | 4.67 |
| 464.54 | 4.72 | 4.72 |
| 462.62 | 5.56 | 5.56 |
| 369.40 | 1.74 | 1.74 |
| 355.37 | 4.12 | 4.12 |
| 438.60 | 4.90 | 4.90 |
| 331.38 | 4.93 | 4.93 |
| 509.99 | 4.95 | 4.95 |
| 307.31 | 2.26 | 2.26 |
| 553.91 | 4.41 | 4.41 |
| 436.48 | 3.14 | 3.14 |
| 254.29 | 3.70 | 3.70 |
| 318.37 | 2.07 | 2.07 |
| 499.54 | 4.10 | 4.10 |
| 535.19 | 4.93 | 4.93 |
| 494.02 | 4.44 | 4.44 |
| 378.53 | 5.29 | 5.29 |
| 968.85 | 13.59 | 13.59 |
| 261.28 | 3.27 | 3.27 |
| 320.39 | 4.52 | 4.52 |
| 516.50 | 4.00 | 4.00 |
| 342.48 | 4.00 | 4.00 |
| 758.84 | 9.31 | 9.31 |
| 329.38 | 3.32 | 3.32 |
| 641.81 | 5.39 | 5.39 |
| 274.32 | 3.08 | 3.08 |
| 455.47 | 4.54 | 4.54 |
| 370.03 | 4.86 | 4.86 |
| 445.46 | -0.15 | -0.15 |
| 363.37 | 4.34 | 4.34 |
| 415.41 | 2.44 | 2.44 |
| 279.70 | 3.02 | 3.02 |
| 571.66 | 5.88 | 5.88 |
| 472.44 | 2.95 | 2.95 |
| 518.59 | 5.22 | 5.22 |
| 296.16 | 3.54 | 3.54 |