Basic Information
ID: ALA1963898
Type: Functional
Description: PUBCHEM_BIOASSAY: Dose response confirmation of uHTS hits for small molecule modulators of myocardial damage in HL-1 cells using 2-dexoy-glucose. (Class of assay: confirmatory)
Tissue: Myocardium
Cell type: HL-1
Activity Charts
Bioactivity
Activity Types for Assay ALA1963898
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 291.31 | 3.03 | 3.03 |
| 456.50 | 5.38 | 5.38 |
| 496.56 | 2.93 | 2.93 |
| 450.52 | 4.44 | 4.44 |
| 537.55 | 3.51 | 3.51 |
| 394.43 | 2.90 | 2.90 |
| 493.61 | 5.71 | 5.71 |
| 478.48 | 3.14 | 3.14 |
| 405.48 | 2.99 | 2.99 |
| 469.54 | 5.01 | 5.01 |
| 453.56 | 3.32 | 3.32 |
| 493.55 | 3.02 | 3.02 |
| 513.57 | 3.33 | 3.33 |
| 475.57 | 1.33 | 1.33 |
| 451.55 | 4.37 | 4.37 |
| 406.44 | 2.37 | 2.37 |
| 501.59 | 5.05 | 5.05 |
| 470.96 | 3.56 | 3.56 |
| 341.28 | 3.29 | 3.29 |
| 485.54 | 2.01 | 2.01 |
| 508.65 | 5.32 | 5.32 |
| 377.43 | 3.19 | 3.19 |
| 352.35 | 2.44 | 2.44 |
| 281.25 | 1.60 | 1.60 |
| 436.51 | 2.91 | 2.91 |
| 427.55 | 4.84 | 4.84 |
| 471.63 | 6.14 | 6.14 |
| 329.40 | 2.82 | 2.82 |
| 541.61 | 3.05 | 3.05 |
| 443.50 | 3.27 | 3.27 |
| 326.40 | 2.80 | 2.80 |
| 487.56 | 3.26 | 3.26 |
| 318.34 | 3.31 | 3.31 |
| 386.46 | 3.93 | 3.93 |
| 509.59 | 2.99 | 2.99 |
| 456.45 | 3.83 | 3.83 |
| 428.51 | 3.63 | 3.63 |
| 447.49 | 5.63 | 5.63 |
| 583.60 | 3.50 | 3.50 |
| 341.32 | 2.40 | 2.40 |
| 403.51 | 3.65 | 3.65 |
| 426.48 | 4.08 | 4.08 |
| 486.57 | 4.84 | 4.84 |
| 317.35 | 3.24 | 3.24 |
| 262.27 | 2.86 | 2.86 |
| 445.48 | 4.67 | 4.67 |
| 468.51 | 3.40 | 3.40 |
| 523.62 | 3.38 | 3.38 |
| 444.49 | 5.19 | 5.19 |
| 364.36 | 3.86 | 3.86 |
| 500.58 | 1.99 | 1.99 |
| 302.34 | 2.77 | 2.77 |
| 359.38 | 4.28 | 4.28 |
| 416.43 | 0.95 | 0.95 |
| 426.48 | 3.66 | 3.66 |
| 358.40 | 1.36 | 1.36 |
| 468.47 | 4.72 | 4.72 |
| 310.31 | 2.79 | 2.79 |
| 376.44 | 4.40 | 4.40 |
| 432.50 | 5.42 | 5.42 |
| 454.53 | 3.85 | 3.85 |
| 519.56 | 3.37 | 3.37 |
| 335.32 | 3.07 | 3.07 |
| 391.46 | 3.58 | 3.58 |
| 535.58 | 3.48 | 3.48 |
| 365.39 | 2.74 | 2.74 |
| 437.45 | 3.62 | 3.62 |
| 303.33 | 3.22 | 3.22 |
| 499.57 | 5.02 | 5.02 |
| 515.60 | 3.54 | 3.54 |
| 470.55 | 4.29 | 4.29 |
| 507.56 | 3.66 | 3.66 |
| 566.61 | 3.68 | 3.68 |
| 562.98 | 3.80 | 3.80 |
| 553.34 | 4.85 | 4.85 |
| 431.52 | 3.20 | 3.20 |
| 421.45 | 4.18 | 4.18 |
| 491.55 | 6.15 | 6.15 |
| 505.56 | 2.82 | 2.82 |
| 480.52 | 5.12 | 5.12 |
| 398.38 | 2.92 | 2.92 |
| 431.45 | 4.42 | 4.42 |
| 462.55 | 4.42 | 4.42 |
| 386.41 | 4.02 | 4.02 |
| 376.46 | 4.15 | 4.15 |
| 400.43 | 4.28 | 4.28 |
| 480.52 | 5.34 | 5.34 |
| 475.55 | 3.10 | 3.10 |
| 425.51 | 4.11 | 4.11 |
| 422.55 | 3.87 | 3.87 |
| 450.45 | 1.36 | 1.36 |
| 316.36 | 2.31 | 2.31 |
| 432.52 | 3.70 | 3.70 |
| 333.34 | 2.93 | 2.93 |
| 495.56 | 3.69 | 3.69 |
| 405.48 | 4.22 | 4.22 |
| 322.32 | 2.67 | 2.67 |
| 376.44 | 4.26 | 4.26 |
| 374.42 | 4.06 | 4.06 |
| 387.49 | 4.24 | 4.24 |
| 386.46 | 4.36 | 4.36 |
| 469.56 | 3.88 | 3.88 |
| 289.30 | 1.91 | 1.91 |
| 519.56 | 3.37 | 3.37 |
| 394.43 | 4.20 | 4.20 |
| 412.50 | 5.17 | 5.17 |
| 346.39 | 3.56 | 3.56 |
| 463.53 | 3.82 | 3.82 |
| 370.46 | 4.23 | 4.23 |
| 400.48 | 4.32 | 4.32 |
| 386.34 | 4.78 | 4.78 |
| 460.56 | 4.71 | 4.71 |
| 468.49 | 3.02 | 3.02 |
| 453.50 | 3.87 | 3.87 |
| 442.54 | 3.19 | 3.19 |
| 435.48 | 3.41 | 3.41 |
| 362.39 | 3.47 | 3.47 |
| 557.68 | 4.56 | 4.56 |
| 461.51 | 4.45 | 4.45 |
| 406.44 | 4.22 | 4.22 |
| 505.57 | 3.08 | 3.08 |
| 480.52 | 4.84 | 4.84 |
| 486.49 | 1.80 | 1.80 |
| 510.61 | 3.65 | 3.65 |
| 638.53 | 5.41 | 5.41 |
| 437.48 | 3.73 | 3.73 |
| 436.46 | 3.36 | 3.36 |
| 514.55 | 2.58 | 2.58 |
| 514.61 | 3.82 | 3.82 |
| 462.53 | 3.81 | 3.81 |
| 595.70 | 5.87 | 5.87 |
| 462.53 | 3.68 | 3.68 |
| 389.44 | 4.92 | 4.92 |
| 414.46 | 5.18 | 5.18 |
| 542.60 | 3.36 | 3.36 |
| 519.58 | 3.13 | 3.13 |
| 578.71 | 3.81 | 3.81 |
| 542.60 | 3.19 | 3.19 |
| 444.53 | 6.25 | 6.25 |
| 431.90 | 2.74 | 2.74 |
| 528.57 | 2.80 | 2.80 |
| 418.45 | 4.45 | 4.45 |
| 452.51 | 4.72 | 4.72 |
| 304.43 | 2.71 | 2.71 |
| 448.50 | 3.81 | 3.81 |
| 420.47 | 3.91 | 3.91 |
| 384.44 | 4.59 | 4.59 |
| 497.62 | 5.92 | 5.92 |
| 400.44 | 4.20 | 4.20 |
| 502.57 | 5.22 | 5.22 |
| 397.48 | 3.70 | 3.70 |
| 245.24 | 2.35 | 2.35 |
| 404.43 | 3.66 | 3.66 |
| 377.20 | 1.17 | 1.17 |
| 426.48 | 4.14 | 4.14 |
| 427.51 | 3.74 | 3.74 |
| 435.46 | 4.79 | 4.79 |
| 373.39 | 4.58 | 4.58 |
| 429.48 | 4.85 | 4.85 |
| 312.33 | 0.71 | 0.71 |
| 438.49 | 4.33 | 4.33 |
| 507.54 | 4.68 | 4.68 |
| 396.45 | 4.13 | 4.13 |
| 483.55 | 2.72 | 2.72 |
| 459.50 | 4.86 | 4.86 |
| 386.41 | 3.84 | 3.84 |
| 377.20 | 1.17 | 1.17 |
| 433.46 | 4.27 | 4.27 |
| 466.52 | 3.63 | 3.63 |
| 450.52 | 4.01 | 4.01 |
| 506.56 | 2.99 | 2.99 |
| 389.41 | 3.96 | 3.96 |
| 387.44 | 4.57 | 4.57 |
| 412.45 | 4.40 | 4.40 |
| 462.53 | 4.20 | 4.20 |
| 445.48 | 4.47 | 4.47 |
| 325.30 | 1.92 | 1.92 |
| 482.45 | 2.76 | 2.76 |
| 383.40 | 2.97 | 2.97 |
| 482.56 | 3.44 | 3.44 |
| 476.34 | 2.25 | 2.25 |
| 341.37 | 3.39 | 3.39 |
| 410.45 | 3.23 | 3.23 |
| 470.49 | 3.39 | 3.39 |
| 400.48 | 2.16 | 2.16 |
| 387.44 | 3.43 | 3.43 |
| 435.87 | 4.28 | 4.28 |
| 437.25 | 1.65 | 1.65 |
| 420.42 | 3.39 | 3.39 |
| 422.42 | 3.71 | 3.71 |
| 452.47 | 5.11 | 5.11 |
| 423.43 | 4.50 | 4.50 |
| 441.49 | 4.59 | 4.59 |
| 349.42 | 3.69 | 3.69 |
| 476.49 | 4.33 | 4.33 |
| 434.45 | 3.70 | 3.70 |
| 362.39 | 3.71 | 3.71 |
| 343.39 | 3.63 | 3.63 |
| 501.59 | 5.16 | 5.16 |
| 413.39 | 4.09 | 4.09 |
| 325.40 | 2.65 | 2.65 |