Basic Information
ID: ALA1963907
Type: Functional
Description: PUBCHEM_BIOASSAY: TRFRET-based biochemical high throughput dose response assay for inhibitors of the interaction of the Ras and Rab interactor 1 protein (Rin1) and the c-abl oncogene 1, non-receptor tyrosine kinase (Abl). (Class of assay: confirmatory)
Activity Charts
Bioactivity
Activity Types for Assay ALA1963907
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 244.32 | 0.80 | 0.80 |
| 287.31 | 1.94 | 1.94 |
| 258.23 | 2.32 | 2.32 |
| 210.19 | 1.52 | 1.52 |
| 348.31 | 2.69 | 2.69 |
| 320.35 | 1.25 | 1.25 |
| 294.27 | 1.96 | 1.96 |
| 207.19 | -1.32 | -1.32 |
| 193.17 | -1.63 | -1.63 |
| 309.33 | 1.03 | 1.03 |
| 214.26 | 1.09 | 1.09 |
| 448.94 | 5.09 | 5.09 |
| 260.30 | 1.43 | 1.43 |
| 399.48 | 2.98 | 2.98 |
| 368.87 | 3.33 | 3.33 |
| 499.60 | 4.08 | 4.08 |
| 307.37 | 2.78 | 2.78 |
| 368.42 | 3.64 | 3.64 |
| 235.25 | -0.67 | -0.67 |
| 496.59 | 4.59 | 4.59 |
| 432.95 | 3.91 | 3.91 |
| 317.39 | 2.27 | 2.27 |
| 371.46 | 3.20 | 3.20 |
| 198.23 | -0.22 | -0.22 |
| 409.56 | 4.44 | 4.44 |
| 324.41 | 1.40 | 1.40 |
| 358.31 | 1.70 | 1.70 |
| 303.41 | 2.95 | 2.95 |
| 288.37 | 2.77 | 2.77 |
| 476.53 | 2.30 | 2.30 |
| 373.25 | 3.82 | 3.82 |
| 468.98 | 4.21 | 4.21 |
| 300.31 | 3.43 | 3.43 |
| 420.47 | 3.47 | 3.47 |
| 494.58 | 4.19 | 4.19 |
| 284.77 | 1.90 | 1.90 |
| 496.59 | 4.42 | 4.42 |
| 719.76 | 5.11 | 5.11 |
| 538.65 | 4.59 | 4.59 |
| 365.50 | 4.18 | 4.18 |
| 365.22 | 3.92 | 3.92 |
| 459.53 | 0.80 | 0.80 |
| 317.43 | 3.26 | 3.26 |
| 339.39 | 1.25 | 1.25 |
| 272.26 | 1.36 | 1.36 |
| 283.28 | 2.74 | 2.74 |
| 228.21 | -1.46 | -1.46 |
| 430.58 | 4.19 | 4.19 |
| 461.57 | 2.57 | 2.57 |
| 404.54 | 3.94 | 3.94 |
| 441.49 | 3.43 | 3.43 |
| 302.76 | 2.04 | 2.04 |
| 421.57 | 4.40 | 4.40 |
| 334.37 | 2.44 | 2.44 |
| 224.21 | 1.23 | 1.23 |
| 341.81 | 3.44 | 3.44 |
| 437.86 | 3.09 | 3.09 |
| 471.56 | 3.50 | 3.50 |
| 226.23 | 1.25 | 1.25 |
| 356.37 | -0.72 | -0.72 |
| 405.25 | 1.97 | 1.97 |
| 319.21 | 2.55 | 2.55 |
| 402.45 | 1.97 | 1.97 |
| 166.18 | 0.96 | 0.96 |
| 402.48 | 3.59 | 3.59 |
| 323.37 | 2.34 | 2.34 |
| 199.28 | 1.66 | 1.66 |
| 424.55 | 3.36 | 3.36 |
| 446.56 | 4.31 | 4.31 |
| 522.87 | 2.39 | 2.39 |
| 334.47 | 4.19 | 4.19 |
| 303.41 | 3.51 | 3.51 |
| 394.45 | 2.52 | 2.52 |
| 284.77 | 2.78 | 2.78 |
| 350.16 | 2.49 | 2.49 |
| 353.45 | 1.88 | 1.88 |
| 486.04 | 5.07 | 5.07 |
| 327.82 | 4.21 | 4.21 |
| 201.22 | 2.37 | 2.37 |
| 521.57 | 2.51 | 2.51 |
| 346.81 | 4.02 | 4.02 |
| 342.40 | 3.38 | 3.38 |
| 367.24 | 2.57 | 2.57 |
| 441.92 | 3.17 | 3.17 |
| 467.35 | 5.08 | 5.08 |
| 278.27 | 0.68 | 0.68 |
| 336.14 | 3.11 | 3.11 |
| 574.66 | 3.45 | 3.45 |
| 391.47 | 1.46 | 1.46 |
| 385.81 | 2.33 | 2.33 |
| 381.86 | 2.07 | 2.07 |
| 330.41 | 1.65 | 1.65 |
| 281.27 | 1.18 | 1.18 |
| 321.40 | 3.09 | 3.09 |
| 420.54 | 3.64 | 3.64 |
| 324.32 | 3.31 | 3.31 |
| 328.28 | 1.40 | 1.40 |
| 316.36 | 1.77 | 1.77 |
| 487.62 | 3.99 | 3.99 |
| 470.62 | 3.85 | 3.85 |
| 435.50 | 2.83 | 2.83 |
| 260.34 | 1.13 | 1.13 |
| 244.32 | 0.80 | 0.80 |
| 451.91 | 4.25 | 4.25 |
| 342.46 | 3.45 | 3.45 |
| 458.66 | 3.62 | 3.62 |
| 489.56 | 3.97 | 3.97 |
| 348.43 | 1.77 | 1.77 |
| 262.36 | 3.02 | 3.02 |
| 347.40 | 1.55 | 1.55 |
| 297.38 | 3.94 | 3.94 |
| 362.48 | 3.76 | 3.76 |
| 417.53 | 4.87 | 4.87 |
| 360.41 | 2.05 | 2.05 |
| 467.57 | 1.42 | 1.42 |
| 545.62 | 3.63 | 3.63 |
| 459.57 | 3.21 | 3.21 |
| 324.30 | 1.97 | 1.97 |
| 260.25 | 0.65 | 0.65 |
| 432.56 | 3.70 | 3.70 |
| 372.42 | 1.96 | 1.96 |
| 348.23 | 4.55 | 4.55 |
| 481.53 | 3.75 | 3.75 |
| 475.55 | 4.30 | 4.30 |
| 410.38 | 3.71 | 3.71 |
| 290.27 | 0.63 | 0.63 |
| 345.31 | 2.28 | 2.28 |
| 436.99 | 5.64 | 5.64 |
| 392.48 | 3.12 | 3.12 |
| 260.25 | 0.59 | 0.59 |
| 389.53 | 2.50 | 2.50 |
| 354.19 | 4.34 | 4.34 |
| 421.59 | 2.79 | 2.79 |
| 259.39 | 3.66 | 3.66 |
| 317.33 | 2.80 | 2.80 |
| 406.47 | 2.60 | 2.60 |
| 370.41 | 2.82 | 2.82 |
| 323.35 | 1.71 | 1.71 |
| 317.43 | 3.21 | 3.21 |
| 420.90 | 3.95 | 3.95 |
| 440.57 | 1.68 | 1.68 |
| 212.25 | 0.12 | 0.12 |
| 373.37 | -0.24 | -0.24 |
| 502.62 | 3.69 | 3.69 |
| 460.92 | 4.67 | 4.67 |
| 378.79 | 2.60 | 2.60 |
| 474.54 | -0.42 | -0.42 |
| 478.52 | 2.29 | 2.29 |
| 254.31 | 2.59 | 2.59 |
| 386.48 | 4.32 | 4.32 |
| 480.59 | 4.64 | 4.64 |
| 608.78 | 5.94 | 5.94 |
| 683.89 | 4.61 | 4.61 |
| 849.52 | 9.09 | 9.09 |
| 313.79 | 3.90 | 3.90 |
| 580.73 | 5.51 | 5.51 |
| 709.89 | 5.10 | 5.10 |
| 466.54 | 3.31 | 3.31 |
| 322.27 | 2.28 | 2.28 |
| 255.23 | 1.12 | 1.12 |
| 260.34 | 1.13 | 1.13 |
| 218.28 | 2.47 | 2.47 |
| 594.76 | 5.55 | 5.55 |
| 315.33 | 1.17 | 1.17 |
| 421.55 | 4.02 | 4.02 |
| 517.63 | 4.68 | 4.68 |
| 194.24 | 1.12 | 1.12 |
| 544.70 | 4.86 | 4.86 |
| 455.63 | 4.36 | 4.36 |
| 415.53 | 3.90 | 3.90 |
| 705.87 | 4.74 | 4.74 |
| 473.54 | 3.28 | 3.28 |
| 569.62 | 3.93 | 3.93 |
| 544.70 | 4.86 | 4.86 |
| 446.60 | 0.23 | 0.23 |
| 531.59 | 3.24 | 3.24 |
| 696.89 | 6.10 | 6.10 |
| 558.72 | 5.25 | 5.25 |
| 628.54 | -1.69 | -1.69 |
| 214.27 | 1.69 | 1.69 |
| 560.62 | 4.46 | 4.46 |
| 329.38 | 3.15 | 3.15 |
| 562.73 | 3.99 | 3.99 |
| 352.44 | 1.92 | 1.92 |
| 538.65 | 4.59 | 4.59 |
| 546.67 | 3.71 | 3.71 |
| 380.45 | 3.43 | 3.43 |
| 488.40 | 1.23 | 1.23 |
| 554.65 | 3.83 | 3.83 |
| 693.91 | 4.67 | 4.67 |
| 560.70 | 4.10 | 4.10 |
| 378.88 | 3.01 | 3.01 |
| 278.31 | 3.89 | 3.89 |
| 530.67 | 4.47 | 4.47 |
| 466.54 | 3.53 | 3.53 |
| 475.59 | 2.36 | 2.36 |
| 602.74 | 5.67 | 5.67 |
| 470.58 | 3.85 | 3.85 |
| 516.46 | 1.03 | 1.03 |
| 625.76 | 4.15 | 4.15 |
| 214.23 | 1.63 | 1.63 |
| 470.57 | 3.32 | 3.32 |
| 696.89 | 6.10 | 6.10 |
| 580.73 | 5.16 | 5.16 |
| 353.38 | 2.40 | 2.40 |
| 460.54 | 2.29 | 2.29 |
| 651.21 | 3.48 | 3.48 |
| 414.90 | 2.45 | 2.45 |
| 359.45 | 3.12 | 3.12 |
| 485.59 | 3.08 | 3.08 |
| 398.46 | 3.07 | 3.07 |
| 458.52 | 3.80 | 3.80 |
| 409.54 | 4.02 | 4.02 |
| 479.56 | 3.34 | 3.34 |
| 407.52 | 3.63 | 3.63 |
| 456.55 | 3.46 | 3.46 |
| 441.61 | 3.97 | 3.97 |
| 238.24 | 0.47 | 0.47 |
| 329.36 | 1.48 | 1.48 |
| 474.57 | 2.68 | 2.68 |
| 445.53 | 3.51 | 3.51 |
| 359.45 | 3.12 | 3.12 |
| 701.82 | 5.74 | 5.74 |
| 236.27 | 1.62 | 1.62 |
| 456.55 | 3.48 | 3.48 |
| 532.64 | 3.32 | 3.32 |
| 150.14 | 0.25 | 0.25 |
| 646.79 | 2.84 | 2.84 |
| 439.53 | 4.90 | 4.90 |
| 304.43 | 3.14 | 3.14 |