Basic Information
ID: ALA1963910
Type: Functional
Description: PUBCHEM_BIOASSAY: Dose response confirmation of DNMT1 inhibitors in a Fluorescent Molecular Beacon assay. (Class of assay: confirmatory)
Activity Charts
Bioactivity
Activity Types for Assay ALA1963910
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 396.45 | 0.59 | 0.59 |
| 493.55 | 3.65 | 3.65 |
| 444.45 | 3.02 | 3.02 |
| 216.02 | 2.13 | 2.13 |
| 483.64 | 5.45 | 5.45 |
| 333.39 | 3.98 | 3.98 |
| 475.53 | 4.47 | 4.47 |
| 434.54 | 4.11 | 4.11 |
| 362.48 | 4.05 | 4.05 |
| 287.37 | 4.44 | 4.44 |
| 420.52 | 3.72 | 3.72 |
| 273.38 | 4.51 | 4.51 |
| 462.03 | 4.33 | 4.33 |
| 385.38 | 3.96 | 3.96 |
| 220.28 | 2.93 | 2.93 |
| 514.44 | 0.88 | 0.88 |
| 422.49 | 2.28 | 2.28 |
| 526.91 | 4.70 | 4.70 |
| 468.29 | 3.57 | 3.57 |
| 500.40 | 5.74 | 5.74 |
| 447.93 | 3.06 | 3.06 |
| 255.07 | 2.89 | 2.89 |
| 476.55 | 5.02 | 5.02 |
| 416.51 | 4.23 | 4.23 |
| 364.40 | 3.52 | 3.52 |
| 472.50 | 3.33 | 3.33 |
| 344.37 | 1.64 | 1.64 |
| 521.37 | 5.67 | 5.67 |
| 294.29 | 1.56 | 1.56 |
| 366.23 | 4.55 | 4.55 |
| 496.56 | 3.55 | 3.55 |
| 406.53 | 2.39 | 2.39 |
| 298.32 | 2.11 | 2.11 |
| 343.34 | 4.02 | 4.02 |
| 490.54 | 5.25 | 5.25 |
| 374.35 | 3.11 | 3.11 |
| 434.41 | 1.51 | 1.51 |
| 410.47 | 2.12 | 2.12 |
| 541.37 | 3.08 | 3.08 |
| 407.81 | 3.93 | 3.93 |
| 444.45 | 3.02 | 3.02 |
| 412.47 | 5.05 | 5.05 |
| 493.39 | 4.68 | 4.68 |
| 442.46 | 4.12 | 4.12 |
| 209.20 | 0.11 | 0.11 |
| 265.18 | 0.28 | 0.28 |
| 410.47 | 2.12 | 2.12 |
| 416.43 | 3.98 | 3.98 |
| 477.90 | 4.11 | 4.11 |
| 396.45 | 1.73 | 1.73 |
| 515.69 | 4.55 | 4.55 |
| 453.40 | 4.41 | 4.41 |
| 466.54 | 3.90 | 3.90 |
| 460.52 | 4.22 | 4.22 |
| 322.32 | 3.34 | 3.34 |
| 457.27 | 5.04 | 5.04 |
| 255.25 | 4.43 | 4.43 |
| 450.52 | 3.18 | 3.18 |
| 435.47 | 2.88 | 2.88 |
| 546.67 | 5.72 | 5.72 |
| 315.37 | 5.11 | 5.11 |
| 385.47 | 4.53 | 4.53 |
| 367.34 | 1.86 | 1.86 |
| 323.33 | 2.69 | 2.69 |
| 208.17 | 0.25 | 0.25 |
| 390.38 | 3.05 | 3.05 |
| 354.36 | 3.21 | 3.21 |
| 425.47 | 2.83 | 2.83 |
| 313.34 | 1.10 | 1.10 |
| 326.31 | 1.95 | 1.95 |
| 546.45 | 6.51 | 6.51 |
| 527.00 | 3.30 | 3.30 |
| 245.37 | 3.94 | 3.94 |
| 304.37 | 2.26 | 2.26 |
| 350.76 | 4.52 | 4.52 |
| 322.30 | 0.67 | 0.67 |
| 343.38 | 1.99 | 1.99 |
| 512.97 | 2.92 | 2.92 |
| 296.28 | 2.25 | 2.25 |
| 420.83 | 4.20 | 4.20 |
| 386.79 | 2.65 | 2.65 |
| 347.42 | 3.50 | 3.50 |
| 498.81 | 4.97 | 4.97 |
| 418.47 | 1.37 | 1.37 |
| 378.43 | 3.91 | 3.91 |
| 476.41 | 4.20 | 4.20 |
| 345.45 | 3.38 | 3.38 |
| 523.46 | 4.23 | 4.23 |
| 493.61 | 4.86 | 4.86 |
| 329.83 | 3.83 | 3.83 |
| 307.42 | 4.29 | 4.29 |
| 415.42 | 3.63 | 3.63 |
| 293.26 | 0.67 | 0.67 |
| 498.54 | 3.51 | 3.51 |
| 383.40 | 3.86 | 3.86 |
| 449.50 | 3.12 | 3.12 |
| 237.31 | 3.29 | 3.29 |
| 318.59 | 4.19 | 4.19 |
| 385.38 | 1.10 | 1.10 |
| 308.38 | 3.70 | 3.70 |
| 486.60 | 4.87 | 4.87 |
| 234.19 | 0.13 | 0.13 |
| 410.47 | 1.95 | 1.95 |
| 420.47 | 2.62 | 2.62 |
| 469.52 | 3.45 | 3.45 |
| 319.36 | 3.17 | 3.17 |
| 426.52 | 4.15 | 4.15 |
| 388.47 | 2.83 | 2.83 |
| 388.38 | 4.05 | 4.05 |
| 384.44 | 1.56 | 1.56 |
| 484.49 | 3.94 | 3.94 |
| 342.38 | 2.51 | 2.51 |
| 526.53 | 4.11 | 4.11 |
| 319.41 | 3.39 | 3.39 |
| 426.29 | 3.04 | 3.04 |
| 191.19 | 1.50 | 1.50 |
| 483.64 | 5.45 | 5.45 |
| 487.47 | 3.50 | 3.50 |
| 435.53 | 3.50 | 3.50 |
| 496.95 | 2.88 | 2.88 |
| 421.41 | 4.70 | 4.70 |
| 447.61 | 6.02 | 6.02 |
| 486.53 | 4.26 | 4.26 |
| 557.46 | 7.03 | 7.03 |
| 282.30 | 3.45 | 3.45 |
| 459.53 | 6.38 | 6.38 |
| 387.23 | 3.23 | 3.23 |
| 396.86 | 4.15 | 4.15 |
| 445.48 | 3.05 | 3.05 |
| 531.72 | 7.30 | 7.30 |
| 464.52 | 5.15 | 5.15 |
| 484.58 | 4.88 | 4.88 |
| 418.45 | 2.91 | 2.91 |
| 455.44 | 2.96 | 2.96 |
| 296.39 | -1.11 | -1.11 |
| 457.58 | 3.13 | 3.13 |
| 465.56 | 4.22 | 4.22 |
| 482.76 | 5.96 | 5.96 |
| 314.18 | 2.66 | 2.66 |
| 338.32 | 2.91 | 2.91 |
| 324.42 | 3.92 | 3.92 |
| 292.38 | 1.75 | 1.75 |
| 415.45 | 4.21 | 4.21 |
| 455.94 | 5.63 | 5.63 |
| 455.54 | 3.15 | 3.15 |
| 421.45 | 3.25 | 3.25 |
| 491.43 | 3.30 | 3.30 |
| 373.37 | 3.27 | 3.27 |
| 498.81 | 4.97 | 4.97 |
| 473.38 | 4.95 | 4.95 |
| 459.51 | 2.41 | 2.41 |
| 454.70 | 7.75 | 7.75 |
| 408.80 | 3.76 | 3.76 |
| 300.34 | 0.91 | 0.91 |
| 386.88 | 3.13 | 3.13 |
| 307.40 | 2.99 | 2.99 |
| 226.23 | 3.11 | 3.11 |
| 552.61 | 5.30 | 5.30 |
| 492.03 | 6.54 | 6.54 |
| 418.51 | 5.58 | 5.58 |
| 422.82 | 3.82 | 3.82 |
| 230.27 | 4.05 | 4.05 |
| 406.19 | 2.81 | 2.81 |
| 505.00 | 5.23 | 5.23 |
| 176.12 | -2.81 | -2.81 |
| 218.21 | 0.59 | 0.59 |
| 359.36 | 4.40 | 4.40 |
| 258.28 | 3.89 | 3.89 |
| 459.53 | 6.38 | 6.38 |
| 359.36 | 4.40 | 4.40 |
| 282.09 | 2.02 | 2.02 |
| 404.43 | 3.85 | 3.85 |
| 404.46 | 5.06 | 5.06 |
| 408.54 | 6.12 | 6.12 |
| 249.27 | 3.44 | 3.44 |
| 750.54 | 6.19 | 6.19 |
| 485.61 | 3.94 | 3.94 |
| 531.57 | 5.12 | 5.12 |
| 199.21 | 1.11 | 1.11 |
| 333.37 | 2.50 | 2.50 |
| 294.35 | 3.39 | 3.39 |
| 175.02 | 2.30 | 2.30 |
| 439.58 | 5.79 | 5.79 |
| 246.22 | 1.45 | 1.45 |
| 339.40 | 2.51 | 2.51 |
| 185.19 | 1.99 | 1.99 |
| 554.97 | 4.69 | 4.69 |
| 441.44 | 0.96 | 0.96 |
| 543.00 | 2.92 | 2.92 |
| 374.83 | 3.41 | 3.41 |
| 410.81 | 3.73 | 3.73 |
| 403.41 | 4.00 | 4.00 |
| 333.26 | 0.78 | 0.78 |
| 434.41 | 3.08 | 3.08 |
| 403.44 | 3.43 | 3.43 |
| 236.29 | 4.11 | 4.11 |
| 446.42 | 2.69 | 2.69 |
| 549.36 | 4.31 | 4.31 |
| 416.46 | 4.03 | 4.03 |
| 452.26 | 4.45 | 4.45 |