Basic Information
ID: ALA1963915
Type: Functional
Description: PUBCHEM_BIOASSAY: qHTS for Inhibitors of the vitamin D receptor (VDR): Hit Validation using a Beta-Lactamase Assay. (Class of assay: confirmatory)
Activity Charts
Bioactivity
Activity Types for Assay ALA1963915
Potency
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 208.26 | 3.58 | 3.58 |
| 242.27 | 2.75 | 2.75 |
| 252.32 | 2.74 | 2.74 |
| 215.03 | 3.10 | 3.10 |
| 279.30 | 3.81 | 3.81 |
| 471.50 | 6.34 | 6.34 |
| 208.22 | 2.73 | 2.73 |
| 223.23 | 2.31 | 2.31 |
| 307.35 | 3.72 | 3.72 |
| 312.36 | 3.61 | 3.61 |
| 316.33 | 3.75 | 3.75 |
| 351.86 | 2.69 | 2.69 |
| 254.24 | 2.87 | 2.87 |
| 195.17 | 1.65 | 1.65 |
| 249.27 | 2.91 | 2.91 |
| 287.10 | 2.77 | 2.77 |
| 324.38 | 3.49 | 3.49 |
| 328.35 | 1.55 | 1.55 |
| 296.37 | 3.44 | 3.44 |
| 331.35 | 2.62 | 2.62 |
| 294.29 | 1.83 | 1.83 |
| 346.34 | 2.18 | 2.18 |
| 345.42 | 2.90 | 2.90 |
| 245.27 | 0.69 | 0.69 |
| 317.28 | 3.80 | 3.80 |
| 330.29 | 1.53 | 1.53 |
| 290.26 | 1.92 | 1.92 |
| 367.92 | 5.32 | 5.32 |
| 306.32 | 1.89 | 1.89 |
| 290.37 | 3.94 | 3.94 |
| 276.34 | 3.70 | 3.70 |
| 276.34 | 3.70 | 3.70 |
| 398.41 | 5.56 | 5.56 |
| 487.94 | 4.50 | 4.50 |
| 431.54 | 2.81 | 2.81 |
| 401.88 | 3.66 | 3.66 |
| 290.30 | 0.76 | 0.76 |
| 448.94 | 5.09 | 5.09 |
| 369.76 | 3.27 | 3.27 |
| 286.77 | 1.66 | 1.66 |
| 440.40 | 3.26 | 3.26 |
| 442.52 | 3.81 | 3.81 |
| 427.75 | 3.98 | 3.98 |
| 300.31 | 2.95 | 2.95 |
| 335.11 | 4.68 | 4.68 |
| 393.40 | 3.87 | 3.87 |
| 306.67 | 3.23 | 3.23 |
| 374.19 | 3.51 | 3.51 |
| 344.37 | 2.59 | 2.59 |
| 415.30 | 3.60 | 3.60 |
| 381.34 | 2.40 | 2.40 |
| 273.29 | 2.09 | 2.09 |
| 296.32 | 3.36 | 3.36 |
| 248.28 | 2.08 | 2.08 |
| 386.38 | 5.69 | 5.69 |
| 447.55 | 4.45 | 4.45 |
| 305.15 | 4.48 | 4.48 |
| 413.50 | 3.52 | 3.52 |
| 264.32 | 3.93 | 3.93 |
| 421.48 | 2.92 | 2.92 |
| 457.46 | 3.73 | 3.73 |
| 437.93 | 3.08 | 3.08 |
| 298.34 | 3.67 | 3.67 |
| 423.52 | 4.07 | 4.07 |
| 306.67 | 3.23 | 3.23 |
| 332.36 | 3.75 | 3.75 |
| 523.41 | 5.24 | 5.24 |
| 317.26 | 2.70 | 2.70 |
| 373.88 | 3.13 | 3.13 |
| 257.29 | 2.79 | 2.79 |
| 545.77 | 5.74 | 5.74 |
| 446.78 | 4.69 | 4.69 |
| 403.45 | 3.69 | 3.69 |
| 302.29 | 3.56 | 3.56 |
| 401.34 | 5.73 | 5.73 |
| 259.29 | 3.55 | 3.55 |
| 434.45 | 3.43 | 3.43 |
| 332.15 | 4.26 | 4.26 |
| 322.32 | 2.39 | 2.39 |
| 409.88 | 2.52 | 2.52 |
| 243.69 | 3.63 | 3.63 |
| 417.85 | 2.36 | 2.36 |
| 480.96 | 2.61 | 2.61 |
| 359.77 | 3.11 | 3.11 |
| 379.85 | 3.28 | 3.28 |
| 336.35 | 2.81 | 2.81 |
| 415.90 | 3.34 | 3.34 |
| 297.31 | 3.81 | 3.81 |
| 501.07 | 3.43 | 3.43 |
| 268.35 | 2.68 | 2.68 |
| 234.26 | 2.85 | 2.85 |
| 211.20 | 1.35 | 1.35 |
| 487.00 | 2.60 | 2.60 |
| 343.34 | 3.46 | 3.46 |
| 463.32 | 3.90 | 3.90 |
| 397.43 | 1.85 | 1.85 |
| 390.42 | 3.43 | 3.43 |
| 345.66 | 3.93 | 3.93 |
| 437.93 | 3.33 | 3.33 |
| 423.54 | 3.96 | 3.96 |
| 278.31 | 2.77 | 2.77 |
| 451.96 | 3.47 | 3.47 |
| 449.36 | 3.08 | 3.08 |
| 293.12 | 3.64 | 3.64 |
| 442.46 | 3.91 | 3.91 |
| 431.90 | 3.75 | 3.75 |
| 358.35 | 2.12 | 2.12 |
| 332.30 | 2.57 | 2.57 |
| 485.34 | 5.17 | 5.17 |
| 366.24 | 4.61 | 4.61 |
| 331.46 | 4.91 | 4.91 |
| 359.43 | 4.56 | 4.56 |
| 515.42 | 3.97 | 3.97 |
| 301.30 | 3.09 | 3.09 |
| 320.33 | 0.58 | 0.58 |
| 444.53 | 2.60 | 2.60 |
| 351.42 | 2.52 | 2.52 |
| 251.24 | 1.88 | 1.88 |
| 446.50 | 4.59 | 4.59 |
| 271.27 | 3.65 | 3.65 |
| 429.93 | 4.28 | 4.28 |
| 397.34 | 2.28 | 2.28 |
| 271.25 | 3.63 | 3.63 |
| 374.23 | 3.70 | 3.70 |
| 423.54 | 3.96 | 3.96 |
| 364.86 | 5.70 | 5.70 |
| 354.79 | 3.82 | 3.82 |
| 336.34 | 1.57 | 1.57 |
| 305.33 | 3.47 | 3.47 |
| 320.27 | 2.71 | 2.71 |
| 401.47 | 4.23 | 4.23 |
| 419.87 | 3.80 | 3.80 |
| 344.21 | 4.30 | 4.30 |
| 415.30 | 3.63 | 3.63 |
| 291.65 | 2.92 | 2.92 |
| 445.88 | 3.14 | 3.14 |
| 333.37 | 2.95 | 2.95 |
| 428.44 | 5.55 | 5.55 |
| 314.18 | 2.17 | 2.17 |
| 288.37 | 3.69 | 3.69 |
| 304.24 | 2.71 | 2.71 |
| 279.39 | 3.34 | 3.34 |
| 406.42 | 2.77 | 2.77 |
| 239.27 | 2.99 | 2.99 |
| 374.35 | 4.51 | 4.51 |
| 270.36 | 3.58 | 3.58 |
| 388.53 | 4.92 | 4.92 |
| 459.94 | 3.07 | 3.07 |
| 207.15 | -0.53 | -0.53 |
| 429.49 | 3.79 | 3.79 |
| 336.42 | 4.28 | 4.28 |
| 314.38 | 1.04 | 1.04 |
| 301.26 | 1.24 | 1.24 |
| 388.26 | 4.27 | 4.27 |
| 368.39 | 5.55 | 5.55 |
| 447.90 | 3.37 | 3.37 |
| 384.28 | 3.25 | 3.25 |
| 319.40 | 3.56 | 3.56 |
| 419.87 | 3.17 | 3.17 |
| 324.21 | 4.20 | 4.20 |
| 291.31 | 3.28 | 3.28 |
| 487.00 | 2.74 | 2.74 |
| 470.28 | 3.61 | 3.61 |
| 329.83 | 2.50 | 2.50 |
| 491.54 | 4.00 | 4.00 |
| 313.34 | 1.10 | 1.10 |
| 322.32 | 1.77 | 1.77 |
| 417.87 | 3.36 | 3.36 |
| 490.92 | 5.16 | 5.16 |
| 395.43 | 3.11 | 3.11 |
| 445.93 | 4.06 | 4.06 |
| 493.89 | 4.82 | 4.82 |
| 494.98 | 3.00 | 3.00 |
| 389.42 | 3.30 | 3.30 |
| 413.10 | 4.89 | 4.89 |
| 254.25 | 2.89 | 2.89 |
| 517.41 | -0.14 | -0.14 |
| 331.42 | 2.94 | 2.94 |
| 404.17 | 3.53 | 3.53 |
| 455.97 | 3.24 | 3.24 |
| 350.76 | 4.52 | 4.52 |
| 461.50 | 2.28 | 2.28 |
| 388.26 | 4.70 | 4.70 |
| 396.44 | 4.28 | 4.28 |
| 300.27 | 2.56 | 2.56 |
| 285.31 | 1.69 | 1.69 |
| 351.39 | 2.35 | 2.35 |
| 367.43 | 2.63 | 2.63 |
| 440.89 | 4.46 | 4.46 |
| 296.37 | 4.75 | 4.75 |
| 305.40 | 5.01 | 5.01 |
| 468.53 | 3.76 | 3.76 |
| 494.98 | 3.00 | 3.00 |
| 455.97 | 3.24 | 3.24 |
| 347.44 | 4.44 | 4.44 |
| 388.37 | 2.89 | 2.89 |
| 236.25 | 2.67 | 2.67 |
| 455.92 | 3.47 | 3.47 |
| 262.27 | 2.65 | 2.65 |
| 386.38 | 5.69 | 5.69 |
| 288.35 | 3.72 | 3.72 |
| 505.93 | 4.69 | 4.69 |
| 423.83 | 3.63 | 3.63 |
| 471.48 | 4.04 | 4.04 |
| 429.33 | 2.54 | 2.54 |
| 468.59 | 4.60 | 4.60 |
| 332.26 | 2.84 | 2.84 |
| 473.96 | 3.46 | 3.46 |
| 328.73 | 2.48 | 2.48 |
| 374.68 | 4.73 | 4.73 |
| 301.78 | 1.72 | 1.72 |
| 262.22 | 1.92 | 1.92 |
| 319.14 | 1.09 | 1.09 |
| 328.38 | 3.43 | 3.43 |
| 333.34 | 2.35 | 2.35 |
| 354.50 | 4.52 | 4.52 |
| 337.42 | 2.96 | 2.96 |
| 226.32 | 4.25 | 4.25 |
| 374.34 | 2.50 | 2.50 |
| 326.15 | 2.87 | 2.87 |
| 457.55 | 4.16 | 4.16 |
| 513.40 | 5.78 | 5.78 |
| 304.39 | 4.33 | 4.33 |
| 362.82 | 4.08 | 4.08 |
| 371.44 | 4.86 | 4.86 |
| 278.31 | 3.94 | 3.94 |
| 341.84 | 3.61 | 3.61 |
| 364.44 | 5.09 | 5.09 |
| 388.88 | 4.77 | 4.77 |
| 343.45 | 3.40 | 3.40 |
| 326.31 | 3.32 | 3.32 |
| 425.62 | 4.08 | 4.08 |
| 300.32 | 2.80 | 2.80 |
| 341.46 | 4.32 | 4.32 |
| 302.35 | 3.27 | 3.27 |
| 332.15 | 4.03 | 4.03 |
| 290.37 | 3.94 | 3.94 |
| 487.00 | 2.60 | 2.60 |
| 387.46 | 4.08 | 4.08 |
| 410.43 | 3.21 | 3.21 |
| 363.27 | 4.86 | 4.86 |
| 317.19 | 1.42 | 1.42 |
| 419.48 | 3.53 | 3.53 |
| 417.47 | 4.57 | 4.57 |
| 332.31 | 3.57 | 3.57 |
| 250.21 | 1.26 | 1.26 |
| 316.31 | 3.87 | 3.87 |
| 278.31 | 3.94 | 3.94 |
| 311.85 | 3.53 | 3.53 |
| 335.39 | 4.51 | 4.51 |
| 357.19 | 2.89 | 2.89 |
| 445.93 | 3.78 | 3.78 |
| 290.08 | 3.29 | 3.29 |
| 327.31 | 4.66 | 4.66 |
| 303.27 | 3.10 | 3.10 |
| 418.49 | 2.06 | 2.06 |
| 372.17 | 3.40 | 3.40 |
| 509.46 | 3.71 | 3.71 |
| 257.25 | 3.39 | 3.39 |
| 262.70 | 2.68 | 2.68 |
| 320.14 | 2.78 | 2.78 |
| 361.81 | 2.94 | 2.94 |
| 384.65 | 7.31 | 7.31 |
| 255.30 | 2.97 | 2.97 |
| 364.32 | 4.79 | 4.79 |
| 237.26 | 2.74 | 2.74 |
| 350.37 | 3.18 | 3.18 |
| 313.31 | 3.51 | 3.51 |
| 301.71 | 1.81 | 1.81 |
| 311.29 | 3.26 | 3.26 |
| 459.91 | 3.53 | 3.53 |
| 437.82 | 3.06 | 3.06 |
| 440.31 | 3.62 | 3.62 |
| 275.31 | 3.58 | 3.58 |
| 451.96 | 3.47 | 3.47 |
| 356.26 | 4.93 | 4.93 |
| 450.54 | 3.62 | 3.62 |
| 302.28 | 2.57 | 2.57 |
| 419.72 | 4.28 | 4.28 |
| 297.41 | 2.05 | 2.05 |
| 352.35 | 2.39 | 2.39 |
| 313.31 | 3.51 | 3.51 |
| 284.31 | 4.40 | 4.40 |
| 380.81 | 3.73 | 3.73 |
| 322.15 | 4.57 | 4.57 |
| 401.26 | 2.93 | 2.93 |
| 302.33 | 3.08 | 3.08 |
| 295.36 | 4.30 | 4.30 |
| 477.91 | 2.19 | 2.19 |
| 440.21 | 2.67 | 2.67 |
| 463.32 | 3.90 | 3.90 |
| 405.84 | 3.50 | 3.50 |
| 395.50 | 3.83 | 3.83 |
| 361.70 | 2.26 | 2.26 |
| 264.28 | 2.47 | 2.47 |
| 275.39 | 3.53 | 3.53 |
| 262.31 | 3.77 | 3.77 |
| 254.25 | 2.89 | 2.89 |
| 459.91 | 3.45 | 3.45 |
| 311.36 | 4.33 | 4.33 |
| 373.21 | 2.32 | 2.32 |
| 334.64 | 2.35 | 2.35 |
| 362.25 | 4.14 | 4.14 |
| 288.35 | 4.05 | 4.05 |
| 401.33 | 5.25 | 5.25 |
| 277.66 | 3.74 | 3.74 |
| 257.25 | 3.39 | 3.39 |
| 295.38 | 2.97 | 2.97 |
| 531.87 | 4.49 | 4.49 |
| 367.45 | 4.03 | 4.03 |
| 259.31 | 2.67 | 2.67 |
| 362.38 | 2.83 | 2.83 |
| 388.22 | 3.90 | 3.90 |
| 280.28 | 3.04 | 3.04 |
| 363.84 | 2.23 | 2.23 |
| 436.48 | 3.14 | 3.14 |
| 331.80 | 3.70 | 3.70 |
| 391.47 | 2.15 | 2.15 |
| 296.30 | 4.08 | 4.08 |
| 445.94 | 3.88 | 3.88 |
| 342.40 | 4.54 | 4.54 |
| 245.23 | 3.26 | 3.26 |
| 426.38 | 4.60 | 4.60 |
| 298.73 | 3.12 | 3.12 |
| 279.34 | 3.85 | 3.85 |
| 332.15 | 4.25 | 4.25 |
| 444.51 | 4.88 | 4.88 |
| 278.31 | 3.24 | 3.24 |
| 455.92 | 3.47 | 3.47 |
| 338.46 | 4.46 | 4.46 |
| 456.56 | 3.68 | 3.68 |
| 428.50 | 3.62 | 3.62 |
| 265.27 | 2.74 | 2.74 |
| 332.45 | 4.97 | 4.97 |
| 441.95 | 2.93 | 2.93 |
| 289.33 | 3.19 | 3.19 |
| 365.43 | 2.88 | 2.88 |
| 340.41 | 1.46 | 1.46 |
| 420.42 | 4.65 | 4.65 |
| 330.34 | 4.17 | 4.17 |
| 361.27 | 2.69 | 2.69 |
| 302.76 | 4.25 | 4.25 |
| 283.35 | 3.53 | 3.53 |
| 334.40 | 3.49 | 3.49 |
| 357.58 | 3.30 | 3.30 |
| 337.38 | 3.98 | 3.98 |
| 341.31 | 5.38 | 5.38 |
| 386.04 | 4.71 | 4.71 |
| 421.38 | 4.86 | 4.86 |
| 460.32 | 3.97 | 3.97 |
| 322.32 | 1.90 | 1.90 |
| 278.31 | 3.28 | 3.28 |
| 431.43 | 0.72 | 0.72 |
| 354.37 | 1.85 | 1.85 |
| 377.76 | 2.39 | 2.39 |
| 520.35 | 4.79 | 4.79 |
| 352.43 | 4.47 | 4.47 |
| 375.80 | 3.09 | 3.09 |
| 533.25 | 5.62 | 5.62 |
| 312.76 | 3.43 | 3.43 |
| 402.49 | 5.02 | 5.02 |
| 515.46 | 4.64 | 4.64 |
| 423.90 | 4.18 | 4.18 |
| 558.33 | 4.46 | 4.46 |
| 312.76 | 4.59 | 4.59 |
| 403.45 | 3.32 | 3.32 |
| 355.19 | 3.87 | 3.87 |
| 414.51 | 6.19 | 6.19 |
| 451.96 | 3.64 | 3.64 |
| 470.50 | 2.48 | 2.48 |
| 415.23 | 2.90 | 2.90 |
| 337.49 | 5.60 | 5.60 |
| 392.40 | 2.38 | 2.38 |
| 401.88 | 3.66 | 3.66 |
| 314.32 | 2.18 | 2.18 |
| 478.96 | 5.13 | 5.13 |
| 287.75 | 3.06 | 3.06 |
| 285.39 | 1.69 | 1.69 |
| 451.53 | 4.61 | 4.61 |
| 385.27 | 3.62 | 3.62 |
| 346.37 | 3.57 | 3.57 |
| 323.35 | 3.50 | 3.50 |
| 374.40 | 2.19 | 2.19 |
| 309.32 | 2.92 | 2.92 |
| 273.34 | 4.44 | 4.44 |
| 409.42 | 2.99 | 2.99 |
| 269.32 | 3.27 | 3.27 |
| 243.26 | 3.49 | 3.49 |
| 360.33 | 4.20 | 4.20 |
| 445.88 | 2.76 | 2.76 |
| 413.10 | 4.89 | 4.89 |
| 368.40 | 2.24 | 2.24 |
| 357.25 | 2.32 | 2.32 |
| 345.19 | 3.72 | 3.72 |
| 329.74 | 3.40 | 3.40 |
| 328.35 | 2.12 | 2.12 |
| 447.58 | 3.71 | 3.71 |
| 479.97 | 4.08 | 4.08 |
| 370.43 | 3.82 | 3.82 |
| 322.15 | 4.57 | 4.57 |
| 411.53 | 3.81 | 3.81 |
| 423.91 | 2.77 | 2.77 |
| 282.73 | 4.11 | 4.11 |
| 341.39 | 2.65 | 2.65 |
| 327.41 | 3.91 | 3.91 |
| 343.34 | 3.52 | 3.52 |
| 342.40 | 3.61 | 3.61 |
| 451.96 | 3.64 | 3.64 |
| 382.46 | 4.50 | 4.50 |
| 557.68 | 4.56 | 4.56 |
| 392.37 | 2.51 | 2.51 |
| 277.28 | 3.26 | 3.26 |
| 307.44 | 2.83 | 2.83 |
| 254.29 | 3.70 | 3.70 |
| 437.58 | 4.82 | 4.82 |
| 265.34 | 4.19 | 4.19 |
| 375.38 | 3.54 | 3.54 |
| 445.48 | 4.26 | 4.26 |
| 353.33 | 1.82 | 1.82 |
| 306.67 | 3.23 | 3.23 |
| 329.74 | 3.40 | 3.40 |
| 309.32 | 3.14 | 3.14 |
| 428.44 | 5.55 | 5.55 |
| 389.41 | 4.02 | 4.02 |
| 515.79 | 5.52 | 5.52 |
| 465.98 | 3.82 | 3.82 |
| 335.45 | 4.24 | 4.24 |
| 490.92 | 5.16 | 5.16 |
| 390.35 | 4.21 | 4.21 |
| 329.38 | 3.32 | 3.32 |
| 370.40 | 3.09 | 3.09 |
| 370.24 | 4.15 | 4.15 |
| 393.90 | 4.84 | 4.84 |
| 382.45 | 3.29 | 3.29 |
| 303.41 | 3.54 | 3.54 |
| 321.38 | 4.43 | 4.43 |
| 281.36 | 3.69 | 3.69 |
| 392.78 | 3.09 | 3.09 |
| 393.51 | 4.78 | 4.78 |
| 236.27 | 2.77 | 2.77 |
| 316.32 | 2.63 | 2.63 |
| 348.31 | 4.50 | 4.50 |
| 326.36 | 1.03 | 1.03 |
| 241.29 | 3.28 | 3.28 |
| 401.55 | 2.93 | 2.93 |
| 317.39 | 2.99 | 2.99 |
| 394.81 | 3.36 | 3.36 |
| 353.47 | 4.61 | 4.61 |
| 435.35 | 6.85 | 6.85 |
| 314.73 | 2.88 | 2.88 |
| 348.31 | 4.50 | 4.50 |
| 470.61 | 3.35 | 3.35 |
| 316.11 | 0.69 | 0.69 |
| 490.39 | 5.16 | 5.16 |
| 433.89 | 4.11 | 4.11 |
| 433.89 | 4.11 | 4.11 |
| 465.89 | 3.51 | 3.51 |
| 471.00 | 3.26 | 3.26 |
| 471.84 | 4.10 | 4.10 |
| 455.90 | 4.65 | 4.65 |
| 405.84 | 3.50 | 3.50 |
| 484.92 | 2.14 | 2.14 |
| 419.87 | 3.80 | 3.80 |