Basic Information
ID: ALA1963970
Type: Functional
Description: PubChem BioAssay. Counterscreen for biased ligands (agonists) of the melanocortin 4 receptor (MC4R): Luminescence-based cell-based high throughput dose response assay to identify agonists of heterodimerization of the mu 1 (OPRM1) and delta 1 (OPRD1) opioid receptors. (Class of assay: confirmatory)
Activity Charts
Bioactivity
Activity Types for Assay ALA1963970
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 276.34 | 4.49 | 4.49 |
| 348.45 | 5.21 | 5.21 |
| 448.09 | 6.07 | 6.07 |
| 436.54 | 3.62 | 3.62 |
| 356.42 | 4.14 | 4.14 |
| 476.54 | 6.83 | 6.83 |
| 479.49 | 5.83 | 5.83 |
| 443.58 | 4.80 | 4.80 |
| 534.04 | 4.28 | 4.28 |
| 424.25 | 5.32 | 5.32 |
| 352.42 | 4.41 | 4.41 |
| 366.98 | 5.36 | 5.36 |
| 412.96 | 5.17 | 5.17 |
| 445.52 | 5.14 | 5.14 |
| 533.15 | 5.56 | 5.56 |
| 427.44 | 3.93 | 3.93 |
| 423.56 | 2.97 | 2.97 |
| 384.48 | 3.45 | 3.45 |
| 532.42 | 7.68 | 7.68 |
| 447.60 | 5.46 | 5.46 |
| 374.89 | 5.11 | 5.11 |
| 503.08 | 5.74 | 5.74 |
| 705.66 | 5.71 | 5.71 |
| 527.55 | 5.94 | 5.94 |
| 515.85 | 6.12 | 6.12 |
| 392.88 | 4.35 | 4.35 |
| 372.90 | 4.95 | 4.95 |
| 434.54 | 5.20 | 5.20 |
| 392.54 | 4.61 | 4.61 |
| 411.46 | 4.54 | 4.54 |
| 385.43 | 4.07 | 4.07 |
| 375.45 | 4.95 | 4.95 |
| 450.29 | 5.40 | 5.40 |
| 358.40 | 4.25 | 4.25 |
| 381.48 | 4.13 | 4.13 |
| 445.52 | ||
| 531.05 | 4.74 | 4.74 |
| 395.51 | 3.87 | 3.87 |
| 463.88 | 2.81 | 2.81 |
| 380.45 | 5.12 | 5.12 |
| 428.54 | 4.02 | 4.02 |
| 421.46 | 6.18 | 6.18 |
| 420.00 | 4.68 | 4.68 |
| 448.57 | 6.15 | 6.15 |
| 502.47 | 6.00 | 6.00 |
| 400.46 | 4.64 | 4.64 |
| 310.35 | 3.76 | 3.76 |
| 366.40 | 4.37 | 4.37 |
| 415.81 | 2.95 | 2.95 |
| 325.48 | 3.84 | 3.84 |
| 435.28 | 5.18 | 5.18 |
| 351.43 | 5.28 | 5.28 |
| 421.89 | 3.91 | 3.91 |
| 388.50 | 4.39 | 4.39 |
| 337.40 | 3.71 | 3.71 |
| 408.87 | 5.60 | 5.60 |
| 347.46 | 4.31 | 4.31 |
| 324.33 | 4.39 | 4.39 |
| 421.48 | 5.82 | 5.82 |
| 395.51 | 3.87 | 3.87 |
| 408.31 | 5.89 | 5.89 |
| 383.45 | 5.19 | 5.19 |
| 353.47 | 4.44 | 4.44 |
| 441.94 | 4.19 | 4.19 |
| 361.35 | 4.33 | 4.33 |
| 509.05 | 4.20 | 4.20 |
| 362.82 | 4.08 | 4.08 |
| 394.53 | 5.71 | 5.71 |
| 487.03 | 3.49 | 3.49 |
| 544.70 | 4.87 | 4.87 |
| 341.44 | 3.80 | 3.80 |
| 384.44 | 5.00 | 5.00 |
| 438.42 | 4.87 | 4.87 |
| 408.59 | 5.10 | 5.10 |
| 413.48 | 5.20 | 5.20 |
| 365.91 | 5.42 | 5.42 |
| 399.41 | 4.69 | 4.69 |
| 426.52 | 4.15 | 4.15 |
| 519.52 | 5.00 | 5.00 |
| 487.08 | 6.04 | 6.04 |
| 305.83 | 4.63 | 4.63 |
| 468.45 | 4.93 | 4.93 |
| 438.55 | 5.10 | 5.10 |
| 451.50 | 5.06 | 5.06 |
| 465.20 | 4.04 | 4.04 |
| 427.47 | 6.26 | 6.26 |
| 381.90 | 5.26 | 5.26 |
| 404.91 | 3.85 | 3.85 |
| 406.46 | 4.41 | 4.41 |
| 316.31 | 3.87 | 3.87 |
| 385.45 | 3.83 | 3.83 |
| 391.47 | 3.85 | 3.85 |
| 414.47 | 4.25 | 4.25 |
| 386.86 | 4.74 | 4.74 |
| 393.32 | 5.61 | 5.61 |
| 329.76 | 4.10 | 4.10 |
| 381.26 | 3.93 | 3.93 |
| 399.95 | 4.81 | 4.81 |
| 381.59 | 5.56 | 5.56 |
| 419.51 | 4.14 | 4.14 |
| 363.39 | 4.65 | 4.65 |
| 488.90 | 5.34 | 5.34 |
| 517.57 | 6.45 | 6.45 |
| 535.05 | 4.79 | 4.79 |
| 488.90 | 5.34 | 5.34 |
| 362.45 | 4.75 | 4.75 |
| 424.52 | 4.71 | 4.71 |
| 296.32 | 3.37 | 3.37 |
| 399.45 | 5.24 | 5.24 |
| 484.48 | 5.26 | 5.26 |
| 385.47 | 3.32 | 3.32 |
| 334.21 | 3.26 | 3.26 |
| 379.55 | 6.24 | 6.24 |
| 389.42 | 4.43 | 4.43 |
| 532.54 | 5.31 | 5.31 |
| 496.08 | 5.42 | 5.42 |
| 373.52 | 6.18 | 6.18 |
| 399.56 | 6.71 | 6.71 |
| 585.56 | 5.60 | 5.60 |
| 422.53 | 4.11 | 4.11 |
| 381.23 | 4.62 | 4.62 |
| 403.55 | 6.18 | 6.18 |
| 414.09 | 7.88 | 7.88 |
| 403.55 | 6.18 | 6.18 |
| 482.63 | 4.51 | 4.51 |
| 474.65 | 4.28 | 4.28 |
| 482.11 | 6.30 | 6.30 |
| 398.41 | 4.43 | 4.43 |
| 361.47 | 4.04 | 4.04 |
| 439.13 | 6.94 | 6.94 |
| 452.51 | 4.72 | 4.72 |
| 379.82 | 5.42 | 5.42 |
| 528.48 | 5.70 | 5.70 |
| 495.51 | 4.55 | 4.55 |
| 518.87 | 6.04 | 6.04 |
| 402.91 | 4.69 | 4.69 |
| 471.44 | 5.28 | 5.28 |
| 416.51 | 5.63 | 5.63 |
| 519.49 | 6.06 | 6.06 |
| 413.55 | 5.75 | 5.75 |
| 398.47 | 4.51 | 4.51 |
| 397.81 | 5.56 | 5.56 |
| 403.44 | 4.26 | 4.26 |
| 413.37 | 5.78 | 5.78 |
| 388.45 | 4.83 | 4.83 |
| 422.89 | 5.49 | 5.49 |
| 357.41 | 4.64 | 4.64 |
| 518.87 | 6.04 | 6.04 |
| 369.42 | 4.83 | 4.83 |
| 424.43 | 5.32 | 5.32 |
| 373.41 | 4.25 | 4.25 |
| 363.44 | 4.70 | 4.70 |
| 440.88 | 5.70 | 5.70 |
| 373.39 | 4.58 | 4.58 |
| 455.44 | 5.66 | 5.66 |
| 450.49 | 4.73 | 4.73 |
| 721.65 | 5.41 | 5.41 |
| 333.35 | 3.84 | 3.84 |
| 447.49 | 4.66 | 4.66 |
| 429.48 | 4.85 | 4.85 |
| 379.46 | 4.62 | 4.62 |
| 340.53 | 3.10 | 3.10 |
| 407.93 | 5.24 | 5.24 |
| 330.38 | 4.35 | 4.35 |
| 436.46 | 5.06 | 5.06 |
| 399.45 | 4.84 | 4.84 |
| 534.49 | 6.54 | 6.54 |
| 532.90 | 6.35 | 6.35 |
| 433.38 | 4.96 | 4.96 |
| 756.70 | 6.29 | 6.29 |
| 406.43 | 5.05 | 5.05 |
| 414.47 | 3.95 | 3.95 |
| 433.46 | 4.27 | 4.27 |
| 387.44 | 4.64 | 4.64 |
| 411.38 | 5.26 | 5.26 |
| 422.89 | 5.49 | 5.49 |
| 457.91 | 4.82 | 4.82 |
| 425.41 | 5.65 | 5.65 |
| 359.89 | 4.19 | 4.19 |
| 302.33 | 3.85 | 3.85 |
| 489.47 | 6.05 | 6.05 |
| 405.45 | 4.97 | 4.97 |
| 319.39 | 4.30 | 4.30 |
| 393.44 | 4.55 | 4.55 |
| 530.47 | 6.17 | 6.17 |
| 724.65 | 6.11 | 6.11 |
| 389.41 | 3.96 | 3.96 |
| 435.46 | 4.79 | 4.79 |
| 509.53 | 4.94 | 4.94 |
| 466.53 | 6.55 | 6.55 |
| 487.51 | 5.07 | 5.07 |
| 495.51 | 4.55 | 4.55 |
| 496.51 | 5.07 | 5.07 |
| 450.90 | 5.12 | 5.12 |
| 364.90 | 5.02 | 5.02 |
| 445.48 | 4.47 | 4.47 |
| 372.88 | 4.68 | 4.68 |
| 405.43 | 4.78 | 4.78 |
| 447.49 | 4.66 | 4.66 |
| 478.47 | 5.54 | 5.54 |
| 413.52 | 4.39 | 4.39 |
| 363.37 | 4.90 | 4.90 |
| 420.49 | 4.00 | 4.00 |
| 305.77 | 4.51 | 4.51 |
| 302.42 | 2.92 | 2.92 |
| 441.41 | 5.27 | 5.27 |
| 405.43 | 4.78 | 4.78 |
| 417.47 | 4.65 | 4.65 |
| 425.41 | 5.14 | 5.14 |
| 336.42 | 4.09 | 4.09 |
| 397.81 | 5.56 | 5.56 |
| 346.37 | 4.16 | 4.16 |
| 396.37 | 5.04 | 5.04 |
| 345.38 | 4.77 | 4.77 |
| 376.43 | 3.13 | 3.13 |
| 371.40 | 3.85 | 3.85 |
| 333.44 | 4.17 | 4.17 |
| 376.49 | 4.93 | 4.93 |
| 305.77 | 4.51 | 4.51 |
| 470.53 | 4.11 | 4.11 |
| 428.87 | 4.60 | 4.60 |
| 363.37 | 4.34 | 4.34 |
| 370.46 | 4.69 | 4.69 |
| 440.50 | 4.10 | 4.10 |
| 361.38 | 4.38 | 4.38 |
| 414.85 | 4.15 | 4.15 |
| 358.01 | 6.46 | 6.46 |
| 387.45 | 2.97 | 2.97 |
| 504.66 | 4.29 | 4.29 |
| 324.41 | 3.82 | 3.82 |