Basic Information
ID: ALA1964005
Type: Functional
Description: PUBCHEM_BIOASSAY: Dose Response selectivity of inhibitors of STriatal-Enriched Phosphatase (STEP) in the dual-specificity protein-tyrosine phosphatase VHR Inhibition Assay. (Class of assay: confirmatory)
Activity Charts
Bioactivity
Activity Types for Assay ALA1964005
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 182.22 | -0.25 | -0.25 |
| 335.45 | 2.27 | 2.27 |
| 239.25 | 1.37 | 1.37 |
| 375.34 | 3.94 | 3.94 |
| 315.35 | 3.54 | 3.54 |
| 427.01 | 4.05 | 4.05 |
| 377.42 | 1.20 | 1.20 |
| 476.49 | 5.11 | 5.11 |
| 357.35 | 2.53 | 2.53 |
| 335.43 | 4.57 | 4.57 |
| 495.17 | 4.17 | 4.17 |
| 527.61 | 5.57 | 5.57 |
| 357.52 | 4.63 | 4.63 |
| 387.89 | 4.35 | 4.35 |
| 388.42 | 4.78 | 4.78 |
| 472.56 | 3.33 | 3.33 |
| 316.49 | 3.55 | 3.55 |
| 540.11 | 2.60 | 2.60 |
| 297.31 | 1.87 | 1.87 |
| 389.55 | 2.99 | 2.99 |
| 341.91 | 3.78 | 3.78 |
| 382.44 | 3.79 | 3.79 |
| 339.51 | 3.25 | 3.25 |
| 335.32 | 3.23 | 3.23 |
| 152.11 | -0.22 | -0.22 |
| 470.34 | 5.98 | 5.98 |
| 381.59 | 5.39 | 5.39 |
| 434.52 | 3.38 | 3.38 |
| 371.55 | 5.02 | 5.02 |
| 364.40 | 2.05 | 2.05 |
| 387.44 | 3.33 | 3.33 |
| 264.39 | 2.01 | 2.01 |
| 432.32 | 4.52 | 4.52 |
| 487.51 | 5.41 | 5.41 |
| 396.41 | 3.22 | 3.22 |
| 359.48 | 3.63 | 3.63 |
| 505.35 | 3.90 | 3.90 |
| 518.54 | 3.02 | 3.02 |
| 412.04 | 5.27 | 5.27 |
| 463.88 | 2.81 | 2.81 |
| 329.74 | 3.71 | 3.71 |
| 313.26 | 2.76 | 2.76 |
| 314.34 | 3.59 | 3.59 |
| 330.38 | 4.44 | 4.44 |
| 416.46 | 2.38 | 2.38 |
| 350.49 | 4.49 | 4.49 |
| 325.26 | 4.52 | 4.52 |
| 268.81 | 2.65 | 2.65 |
| 282.45 | 3.08 | 3.08 |
| 402.45 | 2.30 | 2.30 |
| 390.79 | 4.41 | 4.41 |
| 452.09 | 5.73 | 5.73 |
| 535.69 | 2.36 | 2.36 |
| 268.34 | 2.15 | 2.15 |
| 289.34 | 3.23 | 3.23 |
| 319.26 | 2.28 | 2.28 |
| 404.58 | 2.56 | 2.56 |
| 336.33 | 3.00 | 3.00 |
| 331.46 | 1.85 | 1.85 |
| 386.79 | 2.65 | 2.65 |
| 428.29 | 2.75 | 2.75 |
| 387.59 | 5.72 | 5.72 |
| 498.54 | 3.51 | 3.51 |
| 397.54 | 2.69 | 2.69 |
| 406.54 | 5.10 | 5.10 |
| 292.38 | 3.92 | 3.92 |
| 290.37 | 4.03 | 4.03 |
| 438.35 | 3.42 | 3.42 |
| 471.60 | 4.72 | 4.72 |
| 369.33 | 2.08 | 2.08 |
| 430.84 | 4.39 | 4.39 |
| 347.55 | 4.35 | 4.35 |
| 259.27 | 2.93 | 2.93 |
| 318.33 | 3.11 | 3.11 |
| 360.82 | 3.56 | 3.56 |
| 332.32 | 3.16 | 3.16 |
| 303.26 | 3.31 | 3.31 |
| 329.26 | 1.73 | 1.73 |
| 309.37 | 4.18 | 4.18 |
| 250.37 | 1.71 | 1.71 |
| 416.46 | 2.41 | 2.41 |
| 395.53 | 3.24 | 3.24 |
| 277.37 | 2.38 | 2.38 |
| 343.37 | 1.67 | 1.67 |
| 342.26 | 1.96 | 1.96 |
| 308.37 | 3.36 | 3.36 |
| 368.50 | 4.45 | 4.45 |
| 327.88 | 3.53 | 3.53 |
| 344.39 | 1.15 | 1.15 |
| 486.53 | 4.26 | 4.26 |
| 324.37 | 3.06 | 3.06 |
| 524.60 | 4.17 | 4.17 |
| 436.86 | 5.44 | 5.44 |
| 374.19 | 3.76 | 3.76 |
| 346.55 | 4.75 | 4.75 |
| 405.87 | 5.56 | 5.56 |
| 380.49 | 3.60 | 3.60 |
| 441.46 | 3.56 | 3.56 |
| 400.42 | 4.46 | 4.46 |
| 432.32 | 3.96 | 3.96 |
| 439.51 | 4.34 | 4.34 |
| 425.58 | 1.06 | 1.06 |
| 470.64 | 4.88 | 4.88 |
| 378.41 | 3.39 | 3.39 |
| 487.07 | 4.98 | 4.98 |
| 486.57 | 3.62 | 3.62 |
| 386.83 | 4.66 | 4.66 |
| 487.07 | 4.98 | 4.98 |
| 291.36 | 2.49 | 2.49 |
| 329.85 | 2.52 | 2.52 |
| 397.97 | 3.62 | 3.62 |
| 427.57 | 2.63 | 2.63 |
| 280.30 | 2.26 | 2.26 |
| 603.23 | ||
| 253.28 | 3.19 | 3.19 |
| 407.50 | 4.66 | 4.66 |
| 299.24 | 2.37 | 2.37 |
| 333.80 | 3.74 | 3.74 |
| 292.12 | 4.11 | 4.11 |
| 342.42 | 2.89 | 2.89 |
| 314.44 | 0.50 | 0.50 |
| 282.26 | 2.99 | 2.99 |
| 411.49 | 5.77 | 5.77 |
| 251.35 | 2.56 | 2.56 |
| 527.00 | 3.30 | 3.30 |
| 403.41 | 2.52 | 2.52 |
| 514.56 | 1.23 | 1.23 |
| 316.47 | 3.11 | 3.11 |
| 224.17 | 0.08 | 0.08 |
| 298.30 | 1.76 | 1.76 |
| 179.18 | 0.33 | 0.33 |
| 306.23 | 0.58 | 0.58 |
| 417.26 | 4.38 | 4.38 |
| 262.73 | 2.76 | 2.76 |
| 348.74 | 2.55 | 2.55 |
| 408.94 | 4.32 | 4.32 |
| 326.27 | 2.20 | 2.20 |
| 285.26 | 2.06 | 2.06 |
| 375.45 | 2.52 | 2.52 |
| 231.90 | 2.69 | 2.69 |
| 246.22 | 1.45 | 1.45 |
| 332.31 | 3.30 | 3.30 |
| 340.39 | 2.14 | 2.14 |
| 496.37 | 4.37 | 4.37 |
| 373.76 | 3.30 | 3.30 |
| 419.40 | 2.77 | 2.77 |
| 386.25 | 3.34 | 3.34 |
| 352.33 | 2.71 | 2.71 |
| 434.41 | 3.08 | 3.08 |
| 387.44 | 3.73 | 3.73 |
| 361.74 | 2.78 | 2.78 |
| 354.19 | 3.18 | 3.18 |
| 452.51 | 3.12 | 3.12 |
| 348.16 | 3.12 | 3.12 |
| 482.35 | 3.98 | 3.98 |
| 273.37 | 2.05 | 2.05 |
| 372.02 | 3.57 | 3.57 |
| 337.38 | 3.34 | 3.34 |
| 414.87 | 3.30 | 3.30 |
| 419.44 | 3.18 | 3.18 |
| 368.39 | 3.87 | 3.87 |
| 366.27 | 3.34 | 3.34 |
| 389.41 | 3.17 | 3.17 |
| 378.82 | 3.75 | 3.75 |
| 323.31 | 1.48 | 1.48 |
| 374.42 | 3.08 | 3.08 |