Basic Information
ID: ALA1964060
Type: Functional
Description: PUBCHEM_BIOASSAY: SAR analysis of small molecule inhibitors of APOBEC3A DNA Deaminase via a fluorescence-based single-stranded DNA deaminase assay. (Class of assay: confirmatory)
Activity Charts
Bioactivity
Activity Types for Assay ALA1964060
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 237.35 | 2.48 | 2.48 |
| 309.37 | 2.51 | 2.51 |
| 229.28 | 2.85 | 2.85 |
| 333.84 | 4.55 | 4.55 |
| 290.37 | 3.08 | 3.08 |
| 274.35 | 2.13 | 2.13 |
| 415.84 | 2.78 | 2.78 |
| 376.24 | 3.47 | 3.47 |
| 206.18 | -0.87 | -0.87 |
| 207.26 | 1.77 | 1.77 |
| 349.84 | 1.59 | 1.59 |
| 375.18 | 2.15 | 2.15 |
| 519.65 | 2.94 | 2.94 |
| 286.38 | 3.23 | 3.23 |
| 330.73 | 2.04 | 2.04 |
| 288.38 | 2.52 | 2.52 |
| 359.40 | 3.73 | 3.73 |
| 243.31 | 2.84 | 2.84 |
| 484.43 | 2.67 | 2.67 |
| 271.14 | 1.71 | 1.71 |
| 356.41 | 2.04 | 2.04 |
| 399.48 | 2.83 | 2.83 |
| 262.36 | 2.51 | 2.51 |
| 468.66 | 3.47 | 3.47 |
| 257.29 | 2.43 | 2.43 |
| 313.38 | 3.60 | 3.60 |
| 271.28 | 1.62 | 1.62 |
| 375.45 | 4.34 | 4.34 |
| 247.35 | 3.05 | 3.05 |
| 315.33 | 2.30 | 2.30 |
| 310.33 | 1.22 | 1.22 |
| 248.71 | 1.76 | 1.76 |
| 375.86 | 3.24 | 3.24 |
| 357.39 | 3.17 | 3.17 |
| 384.46 | 4.33 | 4.33 |
| 363.24 | 3.45 | 3.45 |
| 343.79 | 5.00 | 5.00 |
| 370.46 | 4.49 | 4.49 |
| 305.72 | 3.37 | 3.37 |
| 411.57 | 3.81 | 3.81 |
| 325.32 | 1.81 | 1.81 |
| 407.50 | 2.86 | 2.86 |
| 296.80 | 4.87 | 4.87 |
| 374.44 | 3.27 | 3.27 |
| 401.95 | 4.75 | 4.75 |
| 369.87 | 2.67 | 2.67 |
| 445.33 | 5.04 | 5.04 |
| 471.92 | 3.20 | 3.20 |
| 369.49 | 2.64 | 2.64 |
| 370.84 | 3.06 | 3.06 |
| 371.45 | 3.07 | 3.07 |
| 395.38 | 3.00 | 3.00 |
| 438.58 | 4.87 | 4.87 |
| 394.91 | 3.06 | 3.06 |
| 289.34 | 3.27 | 3.27 |
| 385.86 | 4.81 | 4.81 |
| 305.79 | 3.77 | 3.77 |
| 374.71 | 6.24 | 6.24 |
| 281.34 | 2.90 | 2.90 |
| 394.53 | 4.89 | 4.89 |
| 364.43 | 3.73 | 3.73 |
| 244.32 | 2.53 | 2.53 |
| 349.83 | 4.02 | 4.02 |
| 299.76 | 3.07 | 3.07 |
| 307.38 | 3.28 | 3.28 |
| 424.46 | 5.57 | 5.57 |
| 411.94 | 3.41 | 3.41 |
| 291.35 | 3.05 | 3.05 |
| 272.38 | 3.17 | 3.17 |
| 435.29 | 4.64 | 4.64 |
| 399.93 | 5.33 | 5.33 |
| 480.57 | 6.12 | 6.12 |
| 356.45 | 3.18 | 3.18 |
| 447.94 | 5.47 | 5.47 |
| 442.57 | 3.41 | 3.41 |
| 397.89 | 2.82 | 2.82 |
| 297.77 | 2.52 | 2.52 |
| 434.47 | 5.21 | 5.21 |
| 373.29 | 3.58 | 3.58 |
| 436.51 | 4.54 | 4.54 |
| 339.48 | 3.18 | 3.18 |
| 389.52 | 2.31 | 2.31 |
| 435.47 | 2.15 | 2.15 |
| 337.47 | 3.41 | 3.41 |
| 501.73 | 5.89 | 5.89 |
| 341.32 | 1.59 | 1.59 |
| 429.23 | 4.96 | 4.96 |
| 433.36 | 5.30 | 5.30 |
| 473.53 | 5.00 | 5.00 |
| 358.42 | 2.67 | 2.67 |
| 374.49 | 3.29 | 3.29 |
| 310.38 | 3.09 | 3.09 |
| 298.34 | 3.47 | 3.47 |
| 320.39 | 3.20 | 3.20 |
| 456.38 | 3.77 | 3.77 |
| 404.29 | 4.22 | 4.22 |
| 442.95 | 3.77 | 3.77 |
| 426.95 | 4.53 | 4.53 |