Antiviral activity against HCMV Toledo infected in human thymus/liver tissue xenografted in SCID mouse assessed as decrease in viral infection at 6.25...

Basic Information

ID: ALA2013871

Type: Functional

Description: Antiviral activity against HCMV Toledo infected in human thymus/liver tissue xenografted in SCID mouse assessed as decrease in viral infection at 6.25 mg/kg, po qd for 28 days measured on day 35 by RT-PCR analysis (Rvb = 67%)

Format: BAO_0000218

Organism: Human betaherpesvirus 5

Strain: strain Toledo

Target:  Human betaherpesvirus 5(ALA371)

Document:  ALA2010769

Antiviral activity against HCMV Toledo infected in human thymus/liver tissue xenografted in SCID mouse assessed as decrease in viral infection at 6.25 mg/kg, po qd for 28 days measured on day 35 by RT-PCR analysis (Rvb = 67%): 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
247.26-0.38-0.38