Basic Information
ID: ALA2014114
Type: Binding
Description: Inhibition of human N-terminal GST-tagged DYRK2 expressed in baculovirus using DYRKtide-F as substrate assessed as inhibition of [33P] incorporation into substrate using [gamma33P]ATP after 10 mins by liquid scintillation counting
Format: BAO_0000019
Organism: Homo sapiens
Target: Dual-specificity tyrosine-phosphorylation regulated kinase 2(ALA4376)
Document: ALA2010722
Inhibition of human N-terminal GST-tagged DYRK2 expressed in baculovirus using DYRKtide-F as substrate assessed as inhibition of [33P] incorporation into substrate using [gamma33P]ATP after 10 mins by liquid scintillation counting: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA2014114
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 269.35 | 2.86 | 2.86 |
| 283.38 | 3.25 | 3.25 |
| 269.35 | 2.94 | 2.94 |
| 311.43 | 4.06 | 4.06 |
| 297.40 | 3.50 | 3.50 |
| 269.35 | 2.94 | 2.94 |
| 271.34 | 3.38 | 3.38 |
| 346.46 | 2.61 | 2.61 |
| 325.46 | 4.41 | 4.41 |
| 283.37 | 3.25 | 3.25 |
| 283.38 | 3.25 | 3.25 |
| 283.37 | 3.25 | 3.25 |
| 297.36 | 2.97 | 2.97 |
| 317.82 | 3.90 | 3.90 |
| 297.40 | 3.51 | 3.51 |
| 311.43 | 3.85 | 3.85 |
| 337.35 | 3.96 | 3.96 |
| 323.32 | 3.65 | 3.65 |