Basic Information
ID: ALA2014418
Type: Binding
Description: Restoration of CFTR deltaF508 mutant trafficking to cell surface in human CFBE41o cells co-expressing halide-sensitive YFP-H148Q/I142L assessed as fluorescence quenching at 1 uM after 24 hrs relative to control
Organism: Homo sapiens
Cell type: CFBE41o
Activity Charts
Bioactivity
Activity Types for Assay ALA2014418
FC
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 264.32 | 2.47 | 2.47 |
| 623.80 | 3.07 | 3.07 |
| 585.77 | 2.61 | 2.61 |
| 571.74 | 2.22 | 2.22 |
| 570.69 | 1.58 | 1.58 |
| 555.68 | 2.15 | 2.15 |
| 566.70 | 2.83 | 2.83 |
| 567.73 | 3.05 | 3.05 |
| 643.83 | 4.27 | 4.27 |
| 646.79 | 2.80 | 2.80 |
| 607.67 | 3.20 | 3.20 |
| 554.69 | 1.56 | 1.56 |
| 581.76 | 3.39 | 3.39 |
| 593.77 | 3.54 | 3.54 |
| 578.75 | 3.72 | 3.72 |
| 567.73 | 3.05 | 3.05 |
| 577.73 | 3.68 | 3.68 |
| 577.73 | 3.68 | 3.68 |