Basic Information
ID: ALA2014668
Type: Binding
Description: Inhibition of Mcl-1 in doxycyclin-stimulated human HeLa cells overexpressing Bad3SA assessed as increase in caspase3/7 activity at 10 uM after 6 hrs by luminescence analysis
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HeLa
Target: Induced myeloid leukemia cell differentiation protein Mcl-1(ALA4361)
Document: ALA2010640
Inhibition of Mcl-1 in doxycyclin-stimulated human HeLa cells overexpressing Bad3SA assessed as increase in caspase3/7 activity at 10 uM after 6 hrs by luminescence analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA2014668
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 374.40 | 4.78 | 4.78 |
| 390.40 | 4.01 | 4.01 |
| 396.41 | 5.79 | 5.79 |
| 215.26 | 2.21 | 2.21 |
| 319.32 | 4.11 | 4.11 |
| 292.34 | 3.89 | 3.89 |
| 412.47 | 5.96 | 5.96 |
| 457.47 | 5.87 | 5.87 |
| 394.48 | 5.59 | 5.59 |
| 389.50 | 4.24 | 4.24 |
| 493.57 | 6.14 | 6.14 |
| 414.40 | 5.93 | 5.93 |
| 475.30 | 6.56 | 6.56 |
| 472.50 | 7.46 | 7.46 |
| 462.53 | 6.66 | 6.66 |