Basic Information
ID: ALA2019530
Type: Binding
Description: Inhibition of human recombinant NAE assessed as inhibition of NEDD8-UbcH12 complex formation at 0.001 to 10 uM after 1.5 hrs by Western blot analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA2019530
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 443.53 | 2.06 | 2.06 |
| 454.47 | -1.64 | -1.64 |
| 462.49 | -0.23 | -0.23 |
| 430.49 | -0.34 | -0.34 |
| 444.51 | 0.05 | 0.05 |
| 430.49 | -0.49 | -0.49 |
| 458.54 | 0.29 | 0.29 |
| 402.43 | -1.12 | -1.12 |
| 444.51 | 0.05 | 0.05 |
| 430.44 | -1.74 | -1.74 |
| 440.44 | -1.10 | -1.10 |
| 442.48 | -0.66 | -0.66 |
| 456.51 | -0.62 | -0.62 |
| 468.54 | -0.32 | -0.32 |
| 578.60 | -2.46 | -2.46 |
| 388.41 | -1.51 | -1.51 |
| 430.49 | -0.49 | -0.49 |
| 388.41 | -1.51 | -1.51 |
| 422.42 | -0.59 | -0.59 |
| 440.48 | -0.73 | -0.73 |
| 402.43 | -1.49 | -1.49 |
| 458.54 | 0.07 | 0.07 |