Assay Report Card

Basic Information

ID: ALA2019636

Type: Binding

Description: Inhibition of human recombinant NAE assessed as inhibition of NEDD8-UbcH12 complex formation at 1 nM after 1.5 hrs by Western blot analysis

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
346.33-2.75-2.75
416.46-0.73-0.73
430.49-0.34-0.34
444.510.050.05
388.41-1.51-1.51
360.35-2.29-2.29
402.43-1.12-1.12