Assay Report Card

Basic Information

ID: ALA2019637

Type: Binding

Description: Inhibition of human recombinant NAE assessed as inhibition of NEDD8-UbcH12 complex formation at 10 nM after 1.5 hrs by Western blot analysis

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
430.49-0.49-0.49
458.540.290.29
402.43-1.12-1.12
442.48-0.66-0.66
388.41-1.51-1.51
360.35-2.29-2.29
426.41-1.13-1.13