Basic Information
ID: ALA2019638
Type: Binding
Description: Inhibition of human recombinant NAE assessed as inhibition of NEDD8-UbcH12 complex formation at <10 nM after 1.5 hrs by Western blot analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA2019638
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 440.44 | -1.10 | -1.10 |
| 468.54 | -0.32 | -0.32 |
| 402.43 | -1.49 | -1.49 |
| 458.54 | 0.07 | 0.07 |
| 416.46 | -1.10 | -1.10 |
| 416.46 | -1.10 | -1.10 |
| 430.49 | -0.71 | -0.71 |
| 450.48 | -0.70 | -0.70 |
| 416.42 | -2.50 | -2.50 |