Basic Information
ID: ALA2019769
Type: Functional
Description: Inhibition of IgE-mediated human LAD2 cell degranulation assessed as beta-hexosaminidase release using p-nitrophenyl-N-acetyl-D-glucosamide as substrate preincubated for 30 mins measured 90 mins after substrate addition by spectrophotometric analysis
Organism: Homo sapiens
Cell type: LAD2
Activity Charts
Bioactivity
Activity Types for Assay ALA2019769
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 369.47 | 2.24 | 2.24 |
| 423.44 | 3.13 | 3.13 |
| 379.47 | 2.11 | 2.11 |
| 431.54 | 2.88 | 2.88 |
| 419.53 | 2.63 | 2.63 |
| 404.47 | 2.27 | 2.27 |
| 456.55 | 3.04 | 3.04 |
| 430.51 | 2.79 | 2.79 |
| 444.54 | 2.80 | 2.80 |
| 458.57 | 3.10 | 3.10 |
| 474.57 | 2.80 | 2.80 |
| 458.57 | 3.28 | 3.28 |
| 512.54 | 3.82 | 3.82 |
| 472.59 | 3.67 | 3.67 |
| 472.59 | 3.84 | 3.84 |
| 474.57 | 2.25 | 2.25 |
| 473.58 | 2.22 | 2.22 |
| 487.56 | 1.74 | 1.74 |
| 488.59 | 2.91 | 2.91 |
| 404.47 | 2.27 | 2.27 |
| 444.54 | 2.80 | 2.80 |
| 458.57 | 3.28 | 3.28 |
| 474.57 | 2.25 | 2.25 |