Basic Information
ID: ALA2020291
Type: Binding
Description: Inhibition of NOD-2 mediated NFkappaB activation in HEK293T cells assessed as inhibition of MDP-induced luciferase activity after 14 hrs by reporter gene assay
Organism: Homo sapiens
Cell type: HEK-293T
Activity Charts
Bioactivity
Activity Types for Assay ALA2020291
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 257.72 | 3.32 | 3.32 |
| 303.34 | 1.86 | 1.86 |
| 273.32 | 1.86 | 1.86 |
| 356.47 | 4.81 | 4.81 |
| 460.00 | 3.54 | 3.54 |
| 315.40 | 2.78 | 2.78 |
| 458.54 | 2.79 | 2.79 |
| 318.31 | 1.76 | 1.76 |
| 286.36 | 2.89 | 2.89 |
| 287.34 | 2.16 | 2.16 |
| 441.55 | 2.70 | 2.70 |
| 281.32 | 2.51 | 2.51 |
| 455.58 | 2.89 | 2.89 |
| 272.33 | 2.58 | 2.58 |
| 307.76 | 2.51 | 2.51 |
| 360.43 | 4.64 | 4.64 |
| 255.25 | 2.45 | 2.45 |
| 467.59 | 3.09 | 3.09 |
| 306.15 | 3.61 | 3.61 |
| 414.51 | 4.67 | 4.67 |
| 386.50 | 4.90 | 4.90 |
| 376.89 | 5.15 | 5.15 |
| 433.96 | 3.15 | 3.15 |
| 444.51 | 2.40 | 2.40 |
| 372.47 | 4.51 | 4.51 |
| 372.47 | 4.90 | 4.90 |
| 399.52 | 2.50 | 2.50 |
| 388.54 | 5.22 | 5.22 |
| 410.50 | 1.98 | 1.98 |
| 337.47 | 3.99 | 3.99 |
| 424.53 | 2.37 | 2.37 |
| 324.42 | 3.93 | 3.93 |
| 447.99 | 3.54 | 3.54 |
| 421.34 | 5.26 | 5.26 |
| 390.91 | 5.19 | 5.19 |
| 425.55 | 2.89 | 2.89 |
| 426.44 | 5.40 | 5.40 |
| 358.44 | 4.51 | 4.51 |
| 441.55 | 2.70 | 2.70 |
| 430.49 | 2.01 | 2.01 |
| 429.54 | 2.50 | 2.50 |
| 456.52 | 2.40 | 2.40 |
| 419.93 | 2.76 | 2.76 |
| 376.89 | 5.15 | 5.15 |
| 427.53 | 2.31 | 2.31 |
| 433.96 | 3.15 | 3.15 |
| 400.52 | 4.94 | 4.94 |
| 312.39 | 4.06 | 4.06 |
| 455.58 | 3.09 | 3.09 |
| 346.41 | 4.64 | 4.64 |
| 439.58 | 3.19 | 3.19 |
| 338.45 | 4.32 | 4.32 |
| 340.49 | 4.65 | 4.65 |
| 386.50 | 4.90 | 4.90 |
| 428.53 | 4.72 | 4.72 |
| 251.29 | 2.50 | 2.50 |
| 374.51 | 5.22 | 5.22 |
| 445.97 | 3.15 | 3.15 |
| 453.56 | 2.70 | 2.70 |
| 371.48 | 4.57 | 4.57 |
| 470.55 | 2.79 | 2.79 |
| 436.54 | 2.37 | 2.37 |
| 413.54 | 2.80 | 2.80 |
| 385.51 | 4.56 | 4.56 |
| 444.51 | 2.40 | 2.40 |
| 422.51 | 3.74 | 3.74 |
| 318.42 | 3.18 | 3.18 |
| 299.76 | 3.54 | 3.54 |