Basic Information
ID: ALA2020642
Type: Binding
Description: Inhibition of human EGFR expressed in human A431 cells using poly(Glu4/Tyr) and [gamma32P]ATP as substrate after 1 hr by scintillation counting
Organism: Homo sapiens
Cell type: A-431
Activity Charts
Bioactivity
Activity Types for Assay ALA2020642
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 333.75 | 4.18 | 4.18 |
| 281.31 | 3.39 | 3.39 |
| 360.21 | 4.15 | 4.15 |
| 446.46 | 5.09 | 5.09 |
| 422.49 | 4.89 | 4.89 |
| 416.44 | 5.08 | 5.08 |
| 416.44 | 5.08 | 5.08 |
| 446.46 | 5.09 | 5.09 |
| 378.20 | 4.29 | 4.29 |
| 334.73 | 4.23 | 4.23 |
| 379.19 | 4.34 | 4.34 |
| 354.37 | 3.57 | 3.57 |
| 355.35 | 3.62 | 3.62 |
| 368.39 | 3.96 | 3.96 |
| 369.38 | 4.01 | 4.01 |
| 415.45 | 5.03 | 5.03 |
| 396.45 | 4.36 | 4.36 |
| 495.33 | 5.85 | 5.85 |
| 452.42 | 5.36 | 5.36 |
| 468.87 | 5.88 | 5.88 |
| 466.50 | 6.24 | 6.24 |
| 467.89 | 5.83 | 5.83 |
| 352.39 | 3.74 | 3.74 |
| 380.45 | 4.44 | 4.44 |
| 394.48 | 4.83 | 4.83 |
| 382.42 | 4.35 | 4.35 |
| 396.45 | 4.74 | 4.74 |
| 382.42 | 4.35 | 4.35 |
| 388.81 | 4.22 | 4.22 |
| 402.84 | 4.61 | 4.61 |
| 416.87 | 5.00 | 5.00 |
| 430.89 | 5.39 | 5.39 |
| 368.39 | 3.88 | 3.88 |
| 382.42 | 4.27 | 4.27 |
| 396.45 | 4.66 | 4.66 |
| 410.47 | 5.05 | 5.05 |
| 396.45 | 4.66 | 4.66 |
| 402.84 | 4.61 | 4.61 |
| 368.39 | 3.88 | 3.88 |
| 382.42 | 4.27 | 4.27 |
| 367.41 | 3.53 | 3.53 |
| 395.46 | 4.31 | 4.31 |
| 445.48 | 5.04 | 5.04 |
| 418.90 | 4.90 | 4.90 |
| 463.35 | 5.00 | 5.00 |
| 459.39 | 5.17 | 5.17 |
| 473.96 | 4.93 | 4.93 |
| 487.99 | 5.32 | 5.32 |
| 453.54 | 4.59 | 4.59 |
| 467.57 | 4.98 | 4.98 |
| 452.56 | 4.24 | 4.24 |
| 463.35 | 5.00 | 5.00 |
| 467.57 | 4.98 | 4.98 |
| 505.43 | 6.17 | 6.17 |
| 516.04 | 6.10 | 6.10 |
| 530.07 | 6.49 | 6.49 |
| 495.62 | 5.76 | 5.76 |
| 509.65 | 6.15 | 6.15 |
| 339.35 | 3.40 | 3.40 |
| 446.46 | 5.09 | 5.09 |
| 495.33 | 5.85 | 5.85 |
| 509.36 | 6.15 | 6.15 |
| 509.36 | 6.15 | 6.15 |
| 482.90 | 6.18 | 6.18 |
| 480.52 | 6.54 | 6.54 |