Basic Information
ID: ALA2020653
Type: Functional
Description: Antagonist activity at human TLR7 expressed in HEK-Blue cells assessed as inhibition of gardiquimod-induced NFkappaB activation by sAP reporter gene assay
Organism: Homo sapiens
Cell type: HEK-Blue
Activity Charts
Bioactivity
Activity Types for Assay ALA2020653
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 829.07 | 8.92 | 8.92 |
| 588.72 | 6.92 | 6.92 |
| 602.75 | 7.31 | 7.31 |
| 630.80 | 8.09 | 8.09 |
| 686.91 | 9.65 | 9.65 |
| 714.96 | 10.57 | 10.57 |
| 771.07 | 12.13 | 12.13 |
| 799.12 | 12.91 | 12.91 |
| 827.18 | 13.69 | 13.69 |
| 857.12 | 9.70 | 9.70 |
| 913.23 | 11.26 | 11.26 |
| 404.47 | 3.92 | 3.92 |
| 374.49 | 3.60 | 3.60 |
| 859.10 | 8.48 | 8.48 |
| 887.15 | 9.26 | 9.26 |
| 943.26 | 10.82 | 10.82 |