Basic Information
ID: ALA2020723
Type: ADME
Description: Inhibition of CYP2E1 in human liver microsomes using chlorzoxazone as substrate preincubated for 5 mins by LC-MS/MS analysis
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsome
Activity Charts
Bioactivity
Activity Types for Assay ALA2020723
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 241.32 | 3.25 | 3.25 |
| 330.41 | 3.88 | 3.88 |
| 320.42 | 5.02 | 5.02 |
| 236.34 | 3.46 | 3.46 |
| 250.37 | 3.85 | 3.85 |
| 222.31 | 3.07 | 3.07 |
| 208.29 | 2.68 | 2.68 |
| 264.39 | 4.24 | 4.24 |
| 278.42 | 4.63 | 4.63 |
| 236.34 | 3.32 | 3.32 |
| 250.37 | 3.71 | 3.71 |
| 234.32 | 3.07 | 3.07 |
| 276.40 | 4.24 | 4.24 |
| 238.31 | 2.05 | 2.05 |
| 266.32 | 2.53 | 2.53 |
| 270.36 | 3.86 | 3.86 |
| 284.38 | 4.17 | 4.17 |
| 312.44 | 4.99 | 4.99 |
| 326.47 | 5.16 | 5.16 |
| 304.80 | 4.52 | 4.52 |
| 349.25 | 4.63 | 4.63 |
| 396.25 | 4.47 | 4.47 |
| 314.37 | 3.56 | 3.56 |
| 346.46 | 5.53 | 5.53 |
| 321.41 | 4.41 | 4.41 |
| 362.45 | 5.66 | 5.66 |
| 376.48 | 5.44 | 5.44 |
| 271.35 | 3.26 | 3.26 |
| 285.37 | 3.65 | 3.65 |
| 255.35 | 3.56 | 3.56 |
| 307.32 | 3.85 | 3.85 |
| 256.33 | 2.83 | 2.83 |