Assay Report Card

Basic Information

ID: ALA2020808

Type: Binding

Description: Restoration of wild type human BSEP trafficking to cell membrane in MDCK2 cells co-expressing NTCP assessed as decrease in [3H]taurocholate accumulation at 10 to 100 uM preincubated for 24 hrs prior incubation with [3H]taurocholate measured after 2 hrs by liquid scintillation counting

Organism: Homo sapiens

Cell type: MDCK2

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
408.583.453.45