Basic Information
ID: ALA2020809
Type: Binding
Description: Restoration of human BSEP E297G mutant trafficking to cell membrane in MDCK2 cells co-expressing NTCP assessed as accumulation of [3H]taurocholate at 100 uM preincubated for 24 hrs prior incubation with [3H]taurocholate measured after 2 hrs by liquid scintillation counting
Organism: Homo sapiens
Cell type: MDCK2
Activity Charts
Bioactivity
Activity Types for Assay ALA2020809
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 408.58 | 3.45 | 3.45 |
| 392.58 | 4.48 | 4.48 |
| 392.58 | 4.48 | 4.48 |
| 392.58 | 4.48 | 4.48 |
| 465.63 | 2.56 | 2.56 |
| 537.70 | 2.37 | 2.37 |