Basic Information
ID: ALA2020811
Type: Binding
Description: Restoration of human BSEP E297G mutant trafficking to cell membrane in MDCK2 cells co-expressing NTCP assessed as decrease in [3H]taurocholate accumulation preincubated for 24 hrs prior incubation with [3H]taurocholate measured after 2 hrs by liquid scintillation counting
Organism: Homo sapiens
Cell type: MDCK2
Activity Charts
Bioactivity
Activity Types for Assay ALA2020811
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 542.85 | 8.87 | 8.87 |
| 649.96 | 9.55 | 9.55 |