Basic Information
ID: ALA2020885
Type: Binding
Description: Restoration of human BSEP E297G mutant trafficking to cell membrane in MDCK2 cells co-expressing NTCP assessed as increase in [3H]taurocholate transport measuring apparent efflux clearance across the apical membrane at 1 mM preincubated for 24 hrs prior incubation with [3H]taurocholate measured after 2 hrs by transcellular transport assay relative to control
Organism: Homo sapiens
Cell type: MDCK2
Activity Charts
Bioactivity
Activity Types for Assay ALA2020885
FC
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 164.20 | 2.09 | 2.09 |