Basic Information
ID: ALA2024743
Type: Binding
Description: Inhibition of N-terminal hexa-histidine tagged human cloned Eg5 (1 to 368 amino acids) expressed in Escherichia coli BL21 (DE3) assessed as reduction in basal ATPase activity by pyruvate kinase/lactate dehydrogenase-linked assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA2024743
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 363.48 | 4.12 | 4.12 |
| 319.47 | 4.67 | 4.67 |
| 303.41 | 3.95 | 3.95 |
| 346.43 | 2.98 | 2.98 |
| 302.42 | 3.53 | 3.53 |
| 345.44 | 4.21 | 4.21 |
| 345.44 | 4.21 | 4.21 |
| 345.44 | 4.21 | 4.21 |
| 301.43 | 4.76 | 4.76 |
| 397.93 | 4.78 | 4.78 |
| 337.46 | 4.81 | 4.81 |
| 397.93 | 4.78 | 4.78 |
| 353.92 | 5.32 | 5.32 |
| 398.37 | 5.43 | 5.43 |
| 333.50 | 4.98 | 4.98 |
| 347.53 | 5.23 | 5.23 |
| 361.55 | 5.79 | 5.79 |
| 361.55 | 5.62 | 5.62 |
| 387.47 | 5.69 | 5.69 |
| 349.50 | 4.68 | 4.68 |
| 365.57 | 5.39 | 5.39 |
| 403.47 | 5.57 | 5.57 |
| 405.52 | 4.33 | 4.33 |
| 361.51 | 4.87 | 4.87 |
| 405.52 | 4.33 | 4.33 |
| 361.51 | 4.87 | 4.87 |
| 335.88 | 5.41 | 5.41 |
| 359.47 | 4.52 | 4.52 |
| 359.47 | 4.52 | 4.52 |
| 359.47 | 4.52 | 4.52 |
| 315.46 | 5.07 | 5.07 |
| 335.88 | 5.41 | 5.41 |
| 359.47 | 4.52 | 4.52 |
| 359.47 | 4.52 | 4.52 |
| 359.47 | 4.52 | 4.52 |
| 315.46 | 5.07 | 5.07 |
| 379.48 | 3.83 | 3.83 |
| 379.48 | 3.83 | 3.83 |
| 335.47 | 4.38 | 4.38 |
| 344.48 | 4.54 | 4.54 |
| 348.52 | 4.13 | 4.13 |
| 390.55 | 4.31 | 4.31 |
| 363.48 | 4.37 | 4.37 |
| 406.51 | 3.22 | 3.22 |
| 362.50 | 3.77 | 3.77 |
| 376.53 | 4.03 | 4.03 |
| 390.55 | 4.37 | 4.37 |
| 397.57 | 4.07 | 4.07 |
| 344.48 | 4.54 | 4.54 |
| 349.50 | 4.16 | 4.16 |
| 348.52 | 4.13 | 4.13 |
| 390.55 | 4.31 | 4.31 |
| 362.50 | 3.77 | 3.77 |
| 376.53 | 4.03 | 4.03 |
| 390.55 | 4.37 | 4.37 |
| 397.57 | 4.07 | 4.07 |