Assay Report Card

Basic Information

ID: ALA2024744

Type: Binding

Description: Inhibition of N-terminal hexa-histidine tagged human cloned Eg5 (1 to 368 amino acids) expressed in Escherichia coli BL21 (DE3) assessed as reduction of MT-stimulated ATPase activity by pyruvate kinase/lactate dehydrogenase-linked assay

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
517.075.595.59
363.484.124.12
393.514.134.13
413.545.285.28
319.474.674.67
377.514.434.43
345.444.214.21
345.444.214.21
345.444.214.21
301.434.764.76
359.474.524.52
359.474.524.52
359.474.524.52
315.465.075.07
335.885.415.41
359.474.524.52
359.474.524.52
359.474.524.52
315.465.075.07