Basic Information
ID: ALA2025296
Type: Functional
Description: Positive allosteric modulation of human mGlu4 receptor expressed in BHK cells assessed as potentiation of glutamate-induced calcium mobilization by FLIPR analysis
Organism: Homo sapiens
Cell type: BHK
Activity Charts
Bioactivity
Activity Types for Assay ALA2025296
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 271.32 | 4.09 | 4.09 |
| 195.22 | 2.62 | 2.62 |
| 289.31 | 4.23 | 4.23 |
| 289.31 | 4.23 | 4.23 |
| 289.31 | 4.23 | 4.23 |
| 272.31 | 3.48 | 3.48 |
| 277.35 | 4.15 | 4.15 |
| 285.35 | 4.40 | 4.40 |
| 285.35 | 4.40 | 4.40 |
| 299.38 | 4.70 | 4.70 |
| 289.31 | 4.23 | 4.23 |
| 339.32 | 5.11 | 5.11 |
| 305.77 | 4.74 | 4.74 |
| 301.35 | 4.10 | 4.10 |
| 287.32 | 3.79 | 3.79 |
| 315.38 | 4.49 | 4.49 |
| 377.45 | 5.67 | 5.67 |
| 345.40 | 4.11 | 4.11 |
| 359.43 | 4.50 | 4.50 |
| 345.40 | 3.85 | 3.85 |
| 398.51 | 4.95 | 4.95 |
| 412.54 | 5.34 | 5.34 |
| 414.51 | 4.19 | 4.19 |
| 358.45 | 4.03 | 4.03 |
| 384.48 | 4.56 | 4.56 |
| 398.51 | 4.95 | 4.95 |
| 400.48 | 3.80 | 3.80 |
| 441.54 | 3.63 | 3.63 |
| 372.43 | 3.55 | 3.55 |
| 414.47 | 3.33 | 3.33 |
| 358.40 | 4.15 | 4.15 |
| 386.46 | 4.93 | 4.93 |
| 398.47 | 5.07 | 5.07 |
| 384.44 | 4.68 | 4.68 |
| 400.44 | 3.92 | 3.92 |
| 358.40 | 4.20 | 4.20 |
| 272.31 | 3.48 | 3.48 |
| 260.30 | 3.42 | 3.42 |
| 259.31 | 4.02 | 4.02 |
| 260.30 | 3.42 | 3.42 |
| 261.33 | 3.42 | 3.42 |
| 249.32 | 3.55 | 3.55 |
| 235.29 | 3.24 | 3.24 |
| 221.26 | 2.93 | 2.93 |