Basic Information
ID: ALA2026780
Type: Binding
Description: Inhibition of mouse recombinant FAP expressed in HEK293 cells assessed as pNA release from Ala-Pro-p-nitroanilide pre-incubated with enzyme for 15 mins prior to substrate addition by fluorescence technique
Organism: Mus musculus
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA2026780
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 214.07 | ||
| 303.41 | 1.17 | 1.17 |
| 407.32 | 2.02 | 2.02 |
| 307.35 | 2.08 | 2.08 |
| 285.35 | 1.25 | 1.25 |
| 277.35 | 0.92 | 0.92 |
| 305.76 | 1.51 | 1.51 |
| 416.31 | 3.76 | 3.76 |
| 341.29 | 1.83 | 1.83 |
| 371.44 | 2.26 | 2.26 |
| 326.18 | 2.24 | 2.24 |
| 339.42 | 2.66 | 2.66 |
| 333.39 | 2.60 | 2.60 |
| 307.35 | 2.08 | 2.08 |
| 323.37 | 0.49 | 0.49 |
| 481.55 | 2.30 | 2.30 |
| 360.39 | 0.85 | 0.85 |
| 454.48 | 2.58 | 2.58 |
| 429.50 | 0.88 | 0.88 |
| 523.58 | 2.61 | 2.61 |
| 374.35 | 0.85 | 0.85 |
| 446.51 | -0.03 | -0.03 |
| 232.28 | 1.04 | 1.04 |
| 331.42 | 1.32 | 1.32 |
| 298.31 | 1.22 | 1.22 |
| 348.37 | 2.37 | 2.37 |
| 348.37 | 2.37 | 2.37 |
| 325.34 | 2.03 | 2.03 |
| 293.27 | 1.18 | 1.18 |
| 343.33 | 2.33 | 2.33 |
| 271.32 | 1.18 | 1.18 |
| 319.36 | 2.25 | 2.25 |
| 335.41 | 2.72 | 2.72 |
| 375.35 | 2.87 | 2.87 |
| 271.32 | 1.32 | 1.32 |
| 321.38 | 2.47 | 2.47 |
| 339.44 | 2.51 | 2.51 |
| 257.29 | 0.93 | 0.93 |
| 287.32 | 0.94 | 0.94 |
| 237.30 | 0.66 | 0.66 |