Inhibition of mouse recombinant FAP expressed in HEK293 cells assessed as pNA release from Ala-Pro-p-nitroanilide pre-incubated with enzyme for 15 min...

Basic Information

ID: ALA2026780

Type: Binding

Description: Inhibition of mouse recombinant FAP expressed in HEK293 cells assessed as pNA release from Ala-Pro-p-nitroanilide pre-incubated with enzyme for 15 mins prior to substrate addition by fluorescence technique

Format: BAO_0000219

Organism: Mus musculus

Cell type: HEK293

Target: Seprase(ALA5769)

Document: ALA2021822

Inhibition of mouse recombinant FAP expressed in HEK293 cells assessed as pNA release from Ala-Pro-p-nitroanilide pre-incubated with enzyme for 15 mins prior to substrate addition by fluorescence technique: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA2026780

IC50

Total(40)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
214.07
303.41	1.17	1.17
407.32	2.02	2.02
307.35	2.08	2.08
285.35	1.25	1.25
277.35	0.92	0.92
305.76	1.51	1.51
416.31	3.76	3.76
341.29	1.83	1.83
371.44	2.26	2.26
326.18	2.24	2.24
339.42	2.66	2.66
333.39	2.60	2.60
307.35	2.08	2.08
323.37	0.49	0.49
481.55	2.30	2.30
360.39	0.85	0.85
454.48	2.58	2.58
429.50	0.88	0.88
523.58	2.61	2.61
374.35	0.85	0.85
446.51	-0.03	-0.03
232.28	1.04	1.04
331.42	1.32	1.32
298.31	1.22	1.22
348.37	2.37	2.37
348.37	2.37	2.37
325.34	2.03	2.03
293.27	1.18	1.18
343.33	2.33	2.33
271.32	1.18	1.18
319.36	2.25	2.25
335.41	2.72	2.72
375.35	2.87	2.87
271.32	1.32	1.32
321.38	2.47	2.47
339.44	2.51	2.51
257.29	0.93	0.93
287.32	0.94	0.94
237.30	0.66	0.66