Inhibition of human seminal plasma DPP4 assessed as pNA release from Gly-Pro-p-nitroanilide substrate pre-incubated with enzyme for 15 min prior to su...

Basic Information

ID: ALA2026783

Type: Binding

Description: Inhibition of human seminal plasma DPP4 assessed as pNA release from Gly-Pro-p-nitroanilide substrate pre-incubated with enzyme for 15 min prior to substrate addition by fluorescence technique

Format: BAO_0000357

Organism: Homo sapiens

Tissue: Plasma

Target: Dipeptidyl peptidase IV(ALA284)

Document: ALA2021822

Inhibition of human seminal plasma DPP4 assessed as pNA release from Gly-Pro-p-nitroanilide substrate pre-incubated with enzyme for 15 min prior to substrate addition by fluorescence technique: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA2026783

IC50

Total(40)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
214.07
303.41	1.17	1.17
407.32	2.02	2.02
307.35	2.08	2.08
285.35	1.25	1.25
277.35	0.92	0.92
305.76	1.51	1.51
416.31	3.76	3.76
341.29	1.83	1.83
371.44	2.26	2.26
326.18	2.24	2.24
339.42	2.66	2.66
333.39	2.60	2.60
307.35	2.08	2.08
323.37	0.49	0.49
481.55	2.30	2.30
360.39	0.85	0.85
454.48	2.58	2.58
429.50	0.88	0.88
523.58	2.61	2.61
374.35	0.85	0.85
446.51	-0.03	-0.03
232.28	1.04	1.04
331.42	1.32	1.32
298.31	1.22	1.22
348.37	2.37	2.37
348.37	2.37	2.37
325.34	2.03	2.03
293.27	1.18	1.18
343.33	2.33	2.33
271.32	1.18	1.18
319.36	2.25	2.25
335.41	2.72	2.72
375.35	2.87	2.87
271.32	1.32	1.32
321.38	2.47	2.47
339.44	2.51	2.51
257.29	0.93	0.93
287.32	0.94	0.94
237.30	0.66	0.66