Basic Information
ID: ALA2026802
Type: Binding
Description: Inhibition of CXCR1/2 in human polymorphonucleate cells assessed as inhibition of CXCL8-induced chemotaxis at 10'-8 M incubated for 15 mins prior to CXCL8-induction measured after 45 mins
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA2026802
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 283.39 | 2.06 | 2.06 |
| 297.25 | 1.50 | 1.50 |
| 375.35 | 1.09 | 1.09 |
| 298.24 | 2.10 | 2.10 |
| 313.25 | 1.52 | 1.52 |
| 327.28 | 1.87 | 1.87 |
| 327.28 | 1.70 | 1.70 |
| 355.33 | 2.47 | 2.47 |
| 339.34 | 2.54 | 2.54 |
| 374.34 | 3.05 | 3.05 |
| 380.37 | 3.11 | 3.11 |
| 364.30 | 2.65 | 2.65 |
| 448.37 | 4.13 | 4.13 |
| 381.36 | 2.51 | 2.51 |
| 364.31 | 1.78 | 1.78 |
| 365.29 | 2.04 | 2.04 |
| 432.30 | 3.66 | 3.66 |
| 394.40 | 3.42 | 3.42 |
| 367.35 | 2.48 | 2.48 |
| 401.38 | 1.63 | 1.63 |
| 298.24 | 2.10 | 2.10 |
| 375.35 | 1.09 | 1.09 |