Basic Information
ID: ALA2026943
Type: Functional
Description: Inhibition of of kynurenine-3-hydroxylase in rat brain assessed as increase in Increase in extracellular kynurenic acid level at 200 mg/kg, ip coadministered with 100 mg/kg kynurenine by in-vivo microdialysis measured up to 335 mins post dose relative to untreated control
Format: BAO_0000218
Organism: Rattus norvegicus
Tissue: Brain
Target: Rattus norvegicus(ALA376)
Document: ALA2021881
Inhibition of of kynurenine-3-hydroxylase in rat brain assessed as increase in Increase in extracellular kynurenic acid level at 200 mg/kg, ip coadministered with 100 mg/kg kynurenine by in-vivo microdialysis measured up to 335 mins post dose relative to untreated control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA2026943
FC
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 490.17 | 1.94 | 1.94 |