Assay Report Card

Basic Information

ID: ALA2026943

Type: Functional

Description: Inhibition of of kynurenine-3-hydroxylase in rat brain assessed as increase in Increase in extracellular kynurenic acid level at 200 mg/kg, ip coadministered with 100 mg/kg kynurenine by in-vivo microdialysis measured up to 335 mins post dose relative to untreated control

Organism: Rattus norvegicus

Tissue: Brain

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
490.171.941.94