Basic Information
ID: ALA2027041
Type: Binding
Description: Inhibition of human 11beta-HSD1 expressed in HEK293 cells assessed as [3H]cortisol production after 60 mins by SPA
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA2027041
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 822.94 | 2.25 | 2.25 |
| 447.94 | 4.14 | 4.14 |
| 461.97 | 4.53 | 4.53 |
| 476.00 | 4.92 | 4.92 |
| 488.01 | 5.01 | 5.01 |
| 476.00 | 4.87 | 4.87 |
| 502.04 | 5.40 | 5.40 |
| 500.02 | 4.78 | 4.78 |
| 514.05 | 5.12 | 5.12 |
| 488.01 | 5.01 | 5.01 |
| 476.00 | 4.87 | 4.87 |
| 502.04 | 5.40 | 5.40 |
| 514.05 | 4.97 | 4.97 |
| 469.01 | 4.02 | 4.02 |
| 495.05 | 4.51 | 4.51 |
| 483.03 | 4.36 | 4.36 |
| 509.07 | 4.90 | 4.90 |
| 521.08 | 4.46 | 4.46 |