Basic Information
ID: ALA2032586
Type: Binding
Description: Inhibition of human recombinant soluble epoxide hydrolase using CMNPC as substrate assessed as appearance of 6-methoxy-2-naphthaldehyde after 10 mins by fluorescence analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA2032586
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 350.03 | 5.94 | 5.94 |
| 333.56 | 5.99 | 5.99 |
| 372.40 | 4.04 | 4.04 |
| 386.51 | 4.78 | 4.78 |
| 448.69 | 6.50 | 6.50 |
| 292.42 | 2.56 | 2.56 |
| 306.45 | 3.21 | 3.21 |
| 306.45 | 3.21 | 3.21 |
| 388.60 | 5.16 | 5.16 |
| 382.55 | 4.78 | 4.78 |
| 461.44 | 5.54 | 5.54 |
| 476.61 | 5.85 | 5.85 |
| 447.42 | 5.41 | 5.41 |
| 398.55 | 4.65 | 4.65 |
| 386.51 | 4.78 | 4.78 |
| 412.53 | 4.34 | 4.34 |
| 418.53 | 5.06 | 5.06 |
| 398.55 | 4.65 | 4.65 |
| 360.47 | 4.25 | 4.25 |
| 356.44 | 3.48 | 3.48 |
| 380.46 | 5.71 | 5.71 |
| 396.57 | 3.49 | 3.49 |
| 336.52 | 4.24 | 4.24 |
| 336.52 | 4.24 | 4.24 |
| 472.67 | 5.10 | 5.10 |
| 402.54 | 4.21 | 4.21 |
| 402.54 | 4.21 | 4.21 |
| 413.56 | 3.88 | 3.88 |
| 344.41 | 3.27 | 3.27 |
| 300.40 | 3.79 | 3.79 |
| 390.48 | 5.00 | 5.00 |
| 328.41 | 3.56 | 3.56 |
| 383.49 | 3.25 | 3.25 |
| 466.63 | 3.71 | 3.71 |
| 342.44 | 3.49 | 3.49 |
| 356.47 | 3.88 | 3.88 |
| 344.41 | 3.27 | 3.27 |
| 260.38 | 4.26 | 4.26 |
| 321.47 | 1.98 | 1.98 |
| 286.30 | 4.16 | 4.16 |
| 512.70 | 5.10 | 5.10 |
| 279.38 | 1.50 | 1.50 |
| 324.35 | 4.05 | 4.05 |
| 502.66 | 4.41 | 4.41 |
| 374.57 | 4.91 | 4.91 |
| 404.56 | 2.18 | 2.18 |
| 354.37 | 4.68 | 4.68 |
| 437.51 | 5.06 | 5.06 |
| 426.56 | 4.43 | 4.43 |
| 472.63 | 4.37 | 4.37 |
| 396.27 | 4.38 | 4.38 |
| 336.38 | 4.38 | 4.38 |
| 338.37 | 4.80 | 4.80 |
| 368.40 | 4.80 | 4.80 |
| 284.40 | 4.09 | 4.09 |
| 386.39 | 5.01 | 5.01 |
| 316.47 | 4.50 | 4.50 |
| 312.41 | 3.98 | 3.98 |
| 320.82 | 4.14 | 4.14 |
| 312.41 | 3.98 | 3.98 |
| 372.47 | 3.72 | 3.72 |
| 362.47 | 5.57 | 5.57 |
| 374.48 | 5.01 | 5.01 |
| 362.47 | 5.57 | 5.57 |
| 374.48 | 5.01 | 5.01 |
| 440.59 | 3.23 | 3.23 |
| 312.46 | 3.89 | 3.89 |
| 440.58 | 4.82 | 4.82 |
| 362.56 | 4.77 | 4.77 |
| 274.41 | 4.51 | 4.51 |
| 266.77 | 4.04 | 4.04 |
| 369.55 | 5.24 | 5.24 |
| 408.45 | 4.31 | 4.31 |
| 274.41 | 4.44 | 4.44 |
| 302.30 | 4.04 | 4.04 |
| 302.46 | 5.26 | 5.26 |
| 440.58 | 4.47 | 4.47 |
| 437.51 | 5.06 | 5.06 |
| 484.51 | 3.56 | 3.56 |
| 348.25 | 5.37 | 5.37 |
| 380.24 | 5.13 | 5.13 |
| 405.40 | 4.52 | 4.52 |
| 290.36 | 3.32 | 3.32 |
| 388.51 | 5.20 | 5.20 |
| 410.60 | 3.88 | 3.88 |
| 578.75 | 5.80 | 5.80 |
| 456.51 | 4.75 | 4.75 |
| 338.49 | 3.09 | 3.09 |
| 458.64 | 4.67 | 4.67 |
| 410.60 | 3.88 | 3.88 |
| 438.65 | 4.66 | 4.66 |
| 394.56 | 3.62 | 3.62 |
| 419.61 | 3.30 | 3.30 |
| 396.53 | 4.42 | 4.42 |
| 332.49 | 3.77 | 3.77 |
| 389.54 | 2.67 | 2.67 |
| 355.48 | 3.61 | 3.61 |
| 472.67 | 3.14 | 3.14 |
| 393.57 | 2.77 | 2.77 |
| 474.61 | 4.87 | 4.87 |
| 433.98 | 4.14 | 4.14 |
| 433.98 | 4.14 | 4.14 |