Basic Information
ID: ALA2032922
Type: Functional
Description: Antagonist activity at rat TRPM8 expressed in CHO cells assessed as inhibition of icilin-induced Ca2+ influx incubated 2.5 mins prior icilin induction by flash luminometry
Organism: Rattus norvegicus
Cell type: CHO
Activity Charts
Bioactivity
Activity Types for Assay ALA2032922
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 283.32 | 4.00 | 4.00 |
| 334.87 | 5.33 | 5.33 |
| 300.43 | 4.68 | 4.68 |
| 258.35 | 3.34 | 3.34 |
| 272.37 | 3.90 | 3.90 |
| 298.41 | 4.29 | 4.29 |
| 334.44 | 4.93 | 4.93 |
| 402.44 | 5.95 | 5.95 |
| 402.44 | 5.95 | 5.95 |
| 402.44 | 5.95 | 5.95 |
| 368.89 | 5.58 | 5.58 |
| 368.89 | 5.58 | 5.58 |
| 368.89 | 5.58 | 5.58 |
| 352.43 | 5.07 | 5.07 |
| 352.43 | 5.07 | 5.07 |
| 352.43 | 5.07 | 5.07 |
| 325.40 | 5.12 | 5.12 |
| 339.43 | 5.37 | 5.37 |
| 373.44 | 5.91 | 5.91 |
| 353.41 | 4.90 | 4.90 |
| 405.42 | 5.69 | 5.69 |
| 405.42 | 5.69 | 5.69 |
| 405.42 | 5.69 | 5.69 |
| 368.42 | 4.83 | 4.83 |
| 366.41 | 4.59 | 4.59 |
| 396.43 | 4.17 | 4.17 |
| 432.47 | 5.96 | 5.96 |
| 436.89 | 6.60 | 6.60 |
| 420.43 | 6.09 | 6.09 |
| 420.43 | 6.09 | 6.09 |
| 420.43 | 6.09 | 6.09 |
| 419.44 | 5.62 | 5.62 |
| 420.43 | 6.09 | 6.09 |
| 404.36 | 5.62 | 5.62 |
| 404.36 | 5.62 | 5.62 |
| 403.38 | 5.28 | 5.28 |
| 421.42 | 5.48 | 5.48 |
| 404.37 | 4.75 | 4.75 |
| 418.39 | 4.76 | 4.76 |
| 414.40 | 6.02 | 6.02 |
| 432.39 | 6.16 | 6.16 |
| 432.39 | 6.16 | 6.16 |
| 432.39 | 6.16 | 6.16 |
| 432.39 | 6.16 | 6.16 |
| 366.36 | 5.60 | 5.60 |
| 428.43 | 6.41 | 6.41 |
| 400.38 | 5.98 | 5.98 |
| 414.40 | 6.02 | 6.02 |
| 414.40 | 6.02 | 6.02 |