Basic Information
ID: ALA2033031
Type: Functional
Description: Inhibition of Smo-mediated Hh signaling in human Shh-light2 cells by luciferase reporter gene assay
Organism: Homo sapiens
Cell type: Shh Light II
Activity Charts
Bioactivity
Activity Types for Assay ALA2033031
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 411.63 | 5.00 | 5.00 |
| 550.70 | 3.26 | 3.26 |
| 421.31 | 4.71 | 4.71 |
| 560.01 | 6.25 | 6.25 |
| 433.42 | 3.64 | 3.64 |
| 479.56 | 4.40 | 4.40 |
| 499.98 | 4.74 | 4.74 |
| 466.52 | 3.49 | 3.49 |
| 515.59 | 5.24 | 5.24 |
| 556.64 | 6.15 | 6.15 |
| 465.53 | 4.09 | 4.09 |
| 495.56 | 4.10 | 4.10 |
| 495.56 | 4.10 | 4.10 |
| 495.56 | 4.10 | 4.10 |
| 499.98 | 4.74 | 4.74 |
| 499.98 | 4.74 | 4.74 |
| 541.63 | 5.76 | 5.76 |
| 555.61 | 4.12 | 4.12 |
| 559.62 | 5.90 | 5.90 |
| 471.58 | 4.36 | 4.36 |
| 471.56 | 4.15 | 4.15 |
| 431.51 | 3.43 | 3.43 |
| 515.59 | 5.24 | 5.24 |
| 455.49 | 3.68 | 3.68 |
| 550.64 | 3.93 | 3.93 |
| 480.55 | 4.48 | 4.48 |
| 461.54 | 4.99 | 4.99 |
| 462.53 | 4.15 | 4.15 |
| 462.53 | 4.18 | 4.18 |
| 468.56 | 4.22 | 4.22 |
| 461.54 | 4.78 | 4.78 |
| 499.98 | 4.74 | 4.74 |
| 483.52 | 4.23 | 4.23 |
| 495.56 | 4.10 | 4.10 |
| 479.56 | 4.40 | 4.40 |
| 483.52 | 4.23 | 4.23 |
| 573.65 | 6.21 | 6.21 |
| 479.56 | 4.40 | 4.40 |
| 555.66 | 6.07 | 6.07 |
| 571.66 | 6.19 | 6.19 |
| 576.07 | 6.41 | 6.41 |
| 555.66 | 6.07 | 6.07 |
| 555.66 | 6.07 | 6.07 |
| 534.42 | 5.40 | 5.40 |
| 543.05 | 4.81 | 4.81 |
| 530.00 | 4.75 | 4.75 |
| 449.46 | 3.93 | 3.93 |
| 491.54 | 5.10 | 5.10 |
| 479.49 | 3.94 | 3.94 |
| 415.45 | 3.27 | 3.27 |
| 539.59 | 5.90 | 5.90 |
| 483.91 | 4.58 | 4.58 |
| 539.59 | 5.90 | 5.90 |
| 499.52 | 5.08 | 5.08 |
| 488.50 | 4.41 | 4.41 |
| 448.48 | 3.74 | 3.74 |
| 444.49 | 4.64 | 4.64 |
| 533.59 | 3.58 | 3.58 |
| 494.53 | 3.45 | 3.45 |
| 444.49 | 4.43 | 4.43 |
| 542.57 | 5.55 | 5.55 |
| 556.59 | 5.86 | 5.86 |
| 559.02 | 6.06 | 6.06 |
| 538.60 | 5.72 | 5.72 |
| 538.60 | 5.72 | 5.72 |
| 482.92 | 4.39 | 4.39 |
| 462.51 | 4.05 | 4.05 |
| 482.92 | 4.39 | 4.39 |