Basic Information
ID: ALA2034024
Type: Functional
Description: Antiproliferative activity against human NCI-H1975 cells harboring EGFR L858R/T790M mutant after 72 hrs by MTS assay
Organism: Homo sapiens
Cell type: NCI-H1975
Activity Charts
Bioactivity
Activity Types for Assay ALA2034024
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 485.95 | 4.39 | 4.39 |
| 446.91 | 4.28 | 4.28 |
| 494.98 | 4.55 | 4.55 |
| 556.67 | 4.59 | 4.59 |
| 400.44 | 4.05 | 4.05 |
| 338.37 | 2.35 | 2.35 |
| 498.59 | 3.80 | 3.80 |
| 528.62 | 3.81 | 3.81 |
| 542.64 | 4.20 | 4.20 |
| 556.67 | 4.59 | 4.59 |
| 512.62 | 4.11 | 4.11 |
| 516.58 | 3.94 | 3.94 |
| 556.67 | 4.59 | 4.59 |
| 554.66 | 4.34 | 4.34 |
| 590.69 | 5.38 | 5.38 |
| 640.75 | 6.54 | 6.54 |
| 604.72 | 5.38 | 5.38 |
| 666.79 | 7.05 | 7.05 |
| 682.79 | 7.18 | 7.18 |
| 696.81 | 6.96 | 6.96 |
| 474.57 | 3.27 | 3.27 |
| 530.63 | 4.03 | 4.03 |
| 528.62 | 3.81 | 3.81 |
| 473.54 | 4.12 | 4.12 |
| 513.60 | 5.05 | 5.05 |
| 515.57 | 3.89 | 3.89 |
| 542.64 | 4.20 | 4.20 |